Dengue Virus Cause of Dengue Fever

The Dengue Fever Originates from Dengue Virus

• Dengue transmission is primarily through bites of infected Aedes mosquitoes, especially Aedes aegypti and Aedes albopictus. Dengue fever is caused by single-stranded RNA viruses of the genus Flavivirus, specifically four serotypes of dengue virus DENV-1, DENV-2, DENV-3, and DENV-4. 

• Each serotype shares approximately 65% of its genome with the others, still they cause the same disease and range of symptoms. Infections with one serotype provide temporary immunity to that specific serotype but not to the other serotypes. For example, an individual who recovers from a DENV-1 infection will be immune to further DENV-1 infections but remains susceptible to DENV-2, DENV-3, and DENV-4 infections. 

• Subsequent infections with different serotypes can place individuals at a greater risk for serious forms such as dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). Some studies have shown that certain serotypes, such as DENV-2 and DENV-4, tend to cause more severe disease than others. Additionally, the presence of a specific serotype in circulation can impact the overall severity of dengue outbreaks. 

Watch our next video to know about “Signs and Symptoms of Dengue Fever!” 

Source1:-Schaefer TJ, Panda PK, Wolford RW. Dengue Fever. [Updated 2022 Nov 14]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK430732/ 

Source2:-Dengue | CDC Yellow Book 2024. (2024). Dengue | CDC Yellow Book 2024. https://wwwnc.cdc.gov/travel/yellowbook/2024/infections-diseases/dengue