Finasteride + Tamsulosin
Find more information about this combination medication at the webpages for finasteride and tamsulosin
Prostatic Neoplasms, Hirsutism ... show more
Advisory
- This medicine contains a combination of 2 drugs finasteride and tamsulosin.
- finasteride and tamsulosin are both used to treat the same disease or symptom but work in different ways in the body.
- Most doctors will advise making sure that each individual medicine is safe and effective before using a combination form.
Drug Status
Government Approvals
None
WHO Essential Medicine
NO
Known Teratogen
Possible
Pharmaceutical Class
5-alpha Reductase Inhibitor and Alpha-Adrenergic Blocker
Controlled Drug Substance
NO
Summary
Tamsulosin and Finasteride are used to treat benign prostatic hyperplasia (BPH), which is an enlarged prostate that can cause difficulties in urination.
Tamsulosin relaxes the muscles in the prostate and bladder neck, improving urine flow. Finasteride reduces the size of the prostate over time by inhibiting the conversion of testosterone to dihydrotestosterone (DHT), a hormone that contributes to prostate growth.
The usual adult daily dose for Tamsulosin is 0.4 mg and for Finasteride is 5 mg. Both are taken orally, once a day.
Common side effects of Tamsulosin include dizziness, headache, and abnormal ejaculation. Finasteride may cause decreased libido, erectile dysfunction, and decreased ejaculate volume. Both can lead to a drop in blood pressure upon standing, causing dizziness or fainting.
Finasteride should not be used by women, especially during pregnancy, due to the risk of birth defects. Tamsulosin should be used with caution in patients with a history of low blood pressure or those taking other blood pressure-lowering medications.
Indications and Purpose
How does combination of Finasteride and Tamsulosin work?
The combination of Finasteride and Tamsulosin is used to treat symptoms of an enlarged prostate, a condition known as benign prostatic hyperplasia (BPH). Finasteride works by reducing the size of the prostate gland. It does this by blocking the conversion of testosterone to dihydrotestosterone (DHT), a hormone that causes prostate growth. Tamsulosin, on the other hand, is an alpha-blocker that helps relax the muscles in the prostate and the bladder neck, making it easier to urinate. Together, these medications help improve urine flow and reduce the symptoms of BPH.
How does combination of Tamsulosin and Finasteride work?
Tamsulosin works by blocking alpha-1 receptors in the smooth muscle of the prostate and bladder neck, leading to muscle relaxation and improved urine flow. Finasteride acts by inhibiting the enzyme 5-alpha-reductase, which converts testosterone to dihydrotestosterone (DHT), a hormone that causes prostate growth. By reducing DHT levels, Finasteride decreases prostate size over time. Together, they provide both immediate and long-term relief from symptoms of an enlarged prostate.
How effective is combination of Finasteride and Tamsulosin?
The combination of Finasteride and Tamsulosin is often used to treat symptoms of an enlarged prostate, a condition known as benign prostatic hyperplasia (BPH). Finasteride works by reducing the size of the prostate gland, while Tamsulosin helps relax the muscles in the prostate and bladder neck, making it easier to urinate. According to the NHS, this combination can be effective in improving urinary symptoms and reducing the risk of needing surgery for BPH. The National Library of Medicine (NLM) also notes that using both medications together can be more effective than using either one alone, particularly in men with larger prostates. However, it's important to discuss with a healthcare provider to understand the potential side effects and whether this combination is suitable for individual health needs.
How effective is combination of Tamsulosin and Finasteride?
Clinical studies have shown that Tamsulosin effectively improves urinary symptoms by relaxing the muscles in the prostate and bladder neck, leading to better urine flow. Finasteride has been proven to reduce prostate size and lower the risk of acute urinary retention and the need for surgery. When used together, these medications provide a comprehensive approach to managing BPH, offering both immediate symptom relief and long-term benefits. The combination therapy is supported by evidence demonstrating improved patient outcomes compared to monotherapy.
Directions for Use
What is the usual dose of combination of Finasteride and Tamsulosin?
The usual dose for the combination of Finasteride and Tamsulosin is typically one tablet taken once a day. Each tablet usually contains 5 mg of Finasteride and 0.4 mg of Tamsulosin. Finasteride helps to shrink the prostate, while Tamsulosin relaxes the muscles in the prostate and bladder neck, making it easier to urinate. It's important to follow your healthcare provider's instructions and not to adjust the dose without consulting them.
What is the usual dose of combination of Tamsulosin and Finasteride?
The usual adult daily dose for Tamsulosin is 0.4 mg, taken once a day, typically 30 minutes after the same meal each day. For Finasteride, the common dose is 5 mg once daily. Both medications are taken orally and are often prescribed together to manage symptoms of an enlarged prostate. It's important to follow the prescribed dosage and consult a healthcare provider for any adjustments.
How does one take combination of Finasteride and Tamsulosin?
Finasteride and Tamsulosin are medications often used together to treat symptoms of an enlarged prostate, a condition known as benign prostatic hyperplasia (BPH). Finasteride works by reducing the size of the prostate, while Tamsulosin helps relax the muscles in the prostate and bladder neck, making it easier to urinate. When taking these medications, it's important to follow your healthcare provider's instructions. Typically, Tamsulosin is taken once a day, about 30 minutes after the same meal each day, to help with absorption and reduce the risk of side effects like dizziness. Finasteride is usually taken once a day, with or without food. Always take these medications at the same time each day to maintain an even level in your body. Do not crush or chew the tablets, and continue taking them even if you feel well, as it may take several months to notice the full benefits. Consult your healthcare provider for personalized advice, especially if you experience any side effects or have other health conditions.
How does one take combination of Tamsulosin and Finasteride?
Tamsulosin should be taken once daily, 30 minutes after the same meal each day to ensure consistent absorption. Finasteride can be taken with or without food, but it is important to take it at the same time each day for best results. There are no specific food restrictions for either medication, but patients should follow any additional dietary advice provided by their healthcare provider. Consistency in timing helps maintain stable drug levels in the body.
For how long is combination of Finasteride and Tamsulosin taken?
The combination of Finasteride and Tamsulosin is typically taken long-term. These medications are used to treat symptoms of an enlarged prostate, a condition known as benign prostatic hyperplasia (BPH). Finasteride works by reducing the size of the prostate, while Tamsulosin helps relax the muscles in the prostate and bladder neck, making it easier to urinate. The duration of treatment can vary based on individual response and the advice of a healthcare provider. It's important to follow your doctor's instructions and have regular check-ups to assess the effectiveness and any side effects of the treatment. Always consult with your healthcare provider for personalized advice.
For how long is combination of Tamsulosin and Finasteride taken?
Tamsulosin is often used for as long as symptoms persist, which can be indefinitely, depending on the individual's condition and response to treatment. Finasteride is typically used long-term, often for several months to years, to maintain its effects on reducing prostate size. Both medications are generally safe for extended use under medical supervision, and their duration is tailored to the patient's needs and response to therapy.
How long does it take for combination of Finasteride and Tamsulosin to work?
The combination of Finasteride and Tamsulosin is often used to treat symptoms of an enlarged prostate. Finasteride works by reducing the size of the prostate, while Tamsulosin helps relax the muscles in the prostate and bladder neck, making it easier to urinate. According to the NHS, it may take several months for Finasteride to show noticeable effects, as it gradually reduces the size of the prostate. Tamsulosin, on the other hand, can start to improve symptoms within a few days to a week, as it works more quickly to relax the muscles. For the best results, it's important to take these medications as prescribed by your healthcare provider and to have regular follow-ups to monitor your progress.
How long does it take for combination of Tamsulosin and Finasteride to work?
Tamsulosin typically starts working within a few days to improve urine flow and reduce symptoms of an enlarged prostate. Finasteride, on the other hand, may take several months to show noticeable effects as it works by reducing the size of the prostate over time. While Tamsulosin provides quicker relief of symptoms, Finasteride offers long-term benefits by addressing the underlying cause. Together, they complement each other by providing both immediate and sustained relief.
Warnings and Precautions
Are there harms and risks from taking combination of Finasteride and Tamsulosin?
Finasteride and Tamsulosin are often prescribed together to treat symptoms of an enlarged prostate, a condition known as benign prostatic hyperplasia (BPH). While they can be effective, there are potential risks and side effects to be aware of. 1. **Finasteride**: This medication works by reducing the size of the prostate gland. Common side effects include decreased libido, erectile dysfunction, and ejaculation disorders. In some cases, it may also cause breast tenderness or enlargement. 2. **Tamsulosin**: This drug helps relax the muscles in the prostate and bladder neck, making it easier to urinate. Common side effects include dizziness, especially when standing up quickly, runny nose, and ejaculation problems. When taken together, these medications can increase the risk of side effects such as dizziness and sexual dysfunction. It's important to discuss any concerns with a healthcare provider, who can provide guidance based on individual health needs and monitor for any adverse effects. For more detailed information, you can refer to trusted sources like the [NHS](https://www.nhs.uk/), [DailyMeds](https://dailymeds.co.uk/), and [NLM](https://www.nlm.nih.gov/).
Are there harms and risks from taking combination of Tamsulosin and Finasteride?
Common side effects of Tamsulosin include dizziness, headache, and nasal congestion, while Finasteride may cause decreased libido, erectile dysfunction, and breast tenderness. Both medications can cause orthostatic hypotension, a drop in blood pressure upon standing, leading to dizziness or fainting. Serious adverse effects are rare but can include allergic reactions. Patients should report any unusual symptoms to their healthcare provider to ensure safe use of these medications.
Can I take combination of Finasteride and Tamsulosin with other prescription drugs?
Finasteride and Tamsulosin are medications often used together to treat symptoms of an enlarged prostate. Finasteride works by reducing the size of the prostate, while Tamsulosin helps relax the muscles in the prostate and bladder neck, making it easier to urinate. When considering taking these medications with other prescription drugs, it is important to consult with a healthcare professional. This is because both Finasteride and Tamsulosin can interact with other medications, potentially altering their effects or increasing the risk of side effects. For example, Tamsulosin can interact with blood pressure medications, leading to a significant drop in blood pressure. Finasteride may also interact with other drugs that affect hormone levels. Always inform your doctor about all the medications you are currently taking, including over-the-counter drugs and supplements, to ensure safe and effective treatment. For more detailed information, you can refer to trusted sources like the NHS, DailyMeds, or the National Library of Medicine (NLM).
Can I take combination of Tamsulosin and Finasteride with other prescription drugs?
Tamsulosin can interact with other medications that lower blood pressure, such as antihypertensives, increasing the risk of hypotension. It may also interact with certain antibiotics and antifungals that affect liver enzymes. Finasteride has fewer drug interactions but should be used cautiously with other medications affecting hormone levels. Patients should inform their healthcare provider of all medications they are taking to avoid potential interactions and ensure safe use.
Can I take combination of Finasteride and Tamsulosin if I am pregnant?
No, you should not take Finasteride if you are pregnant. Finasteride can cause birth defects, particularly affecting the development of male genitalia in a male fetus. It is important to avoid handling crushed or broken tablets of Finasteride if you are pregnant or may become pregnant. Tamsulosin, on the other hand, is not typically used during pregnancy, and its effects are not well-studied in pregnant women. Always consult with a healthcare professional before taking any medication during pregnancy.
Can I take combination of Tamsulosin and Finasteride if I am pregnant?
Finasteride is contraindicated during pregnancy due to the risk of birth defects, particularly affecting male fetuses. Women who are pregnant or may become pregnant should avoid handling crushed or broken tablets. Tamsulosin is not typically used in women, and its safety during pregnancy has not been established. Both medications are primarily prescribed for men, and women should consult their healthcare provider for safer alternatives if treatment is needed during pregnancy.
Can I take combination of Finasteride and Tamsulosin while breastfeeding?
It is generally not recommended to take Finasteride while breastfeeding. Finasteride is a medication that can affect hormone levels and may pose risks to a breastfeeding infant. Tamsulosin, on the other hand, is used to treat urinary issues and its safety during breastfeeding is not well established. It is crucial to consult with a healthcare professional before taking these medications while breastfeeding to ensure the safety of both the mother and the baby. For more detailed information, you can refer to trusted sources like the NHS or NLM.
Can I take combination of Tamsulosin and Finasteride while breastfeeding?
Tamsulosin and Finasteride are not typically used in women, and there is limited information on their safety during lactation and breastfeeding. Finasteride is contraindicated in women due to the risk of birth defects, and it is not recommended for use during breastfeeding. Tamsulosin's effects on breast milk are unknown, but it is generally not prescribed to breastfeeding women. Women should consult their healthcare provider for alternatives if treatment is necessary.
Who should avoid taking combination of Finasteride and Tamsulosin?
People who should avoid taking the combination of Finasteride and Tamsulosin include: 1. **Women and Children**: Finasteride is not approved for use in women or children. It can cause birth defects, so pregnant women or those who may become pregnant should not handle crushed or broken tablets. 2. **Individuals with Severe Liver Disease**: Both drugs are processed by the liver, so those with severe liver problems should avoid them or use them with caution. 3. **People with Allergies**: Anyone who has had an allergic reaction to Finasteride, Tamsulosin, or any of their ingredients should not take these medications. 4. **Patients with Low Blood Pressure**: Tamsulosin can lower blood pressure, so individuals with already low blood pressure or those taking medications to lower blood pressure should be cautious. 5. **Individuals with Prostate Cancer**: Finasteride can affect the results of a prostate-specific antigen (PSA) test, which is used to screen for prostate cancer. It is important to rule out prostate cancer before starting treatment. Always consult a healthcare professional before starting or stopping any medication.
Who should avoid taking combination of Tamsulosin and Finasteride?
Tamsulosin should be used with caution in patients with a history of low blood pressure or those taking other medications that lower blood pressure, as it can cause dizziness or fainting. Finasteride is contraindicated in women, especially during pregnancy, due to the risk of birth defects. Both medications require careful monitoring in patients with liver impairment. Patients should discuss their medical history with their healthcare provider to ensure these medications are safe for them.