Tamsulosin
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
Alpha-Adrenergic Blocker
Controlled Drug Substance
NO
Tamsulosin
Learn more about this medicine -
Click HereSummary
Tamsulosin is primarily used to treat symptoms of benign prostatic hyperplasia (BPH), which is an enlargement of the prostate in men. It can also help pass kidney stones and may be prescribed for urinary retention or difficulty in urination.
Tamsulosin works by blocking specific receptors in the smooth muscles of the prostate and bladder neck. This action relaxes these muscles, improving urine flow and reducing urinary symptoms associated with BPH.
The usual daily dosage of Tamsulosin for adults is 0.4 mg once daily, taken about 30 minutes after the same meal each day. If necessary, the dose may be increased to 0.8 mg per day. The capsule should be swallowed whole and not crushed or chewed.
Common side effects of Tamsulosin include dizziness, headache, runny or stuffy nose, and ejaculatory dysfunction. Significant adverse effects can include low blood pressure when standing, fainting, severe allergic reactions, and in rare cases, painful prolonged erection or vision problems.
Tamsulosin may cause dizziness, fainting, or low blood pressure, especially after the first dose or dose adjustments. It is not recommended for people with hypersensitivity to the drug. It should be used with caution in patients with severe liver impairment or those undergoing cataract or glaucoma surgery as it can cause a condition known as Intraoperative Floppy Iris Syndrome.
Indications and Purpose
What is Tamsulosin used for?
Tamsulosin is indicated for the treatment of symptoms associated with benign prostatic hyperplasia (BPH) in men. These symptoms include difficulty urinating, weak stream, and frequent or urgent urination. It is not indicated for the treatment of hypertension.
How does Tamsulosin work?
Tamsulosin works by blocking alpha-1 receptors in the prostate and bladder neck, leading to relaxation of smooth muscles. This relaxation helps improve urine flow and reduces symptoms of benign prostatic hyperplasia (BPH), such as difficulty urinating and frequent urination.
Is Tamsulosin effective?
Clinical studies have shown that Tamsulosin effectively improves symptoms of benign prostatic hyperplasia (BPH), such as urinary flow rate and symptom scores. Patients taking Tamsulosin reported significant improvements compared to those on placebo, demonstrating its effectiveness in managing BPH symptoms.
How does one know if Tamsulosin is working?
The benefit of Tamsulosin is evaluated by monitoring improvements in urinary symptoms associated with benign prostatic hyperplasia (BPH), such as increased urine flow rate and reduced symptom scores. Regular follow-up appointments with a healthcare provider help assess the medication's effectiveness.
Directions for Use
What is the usual dose of Tamsulosin?
The usual daily dose for adults is 0.4 mg once daily, taken approximately 30 minutes after the same meal each day. If there is no response after 2 to 4 weeks, the dose may be increased to 0.8 mg once daily. Tamsulosin is not indicated for use in children.
How do I take Tamsulosin?
Take Tamsulosin once daily, about 30 minutes after the same meal each day. Swallow the capsules whole without crushing, chewing, or opening them. There are no specific food restrictions, but taking it with food helps maintain consistent absorption.
For how long do I take Tamsulosin?
Tamsulosin is typically used for long-term management of symptoms associated with benign prostatic hyperplasia (BPH). It helps control the condition but does not cure it, so it may be taken indefinitely as prescribed by a doctor.
How long does it take for Tamsulosin to start working?
Tamsulosin may start to improve symptoms within a week, but it can take up to 4 weeks to experience the full benefits. If symptoms do not improve after this period, consult your doctor for further evaluation.
How should I store Tamsulosin?
Store Tamsulosin in its original container, tightly closed, at room temperature away from excess heat and moisture. Keep it out of reach of children. Do not store it in the bathroom. Dispose of unneeded medication through a take-back program.
Warnings and Precautions
Who should avoid taking Tamsulosin?
Important warnings for Tamsulosin include the risk of dizziness and fainting, especially when standing up quickly. It should not be used in combination with strong CYP3A4 inhibitors. Contraindications include hypersensitivity to Tamsulosin or its components. Patients should inform their doctor of any surgeries, especially eye surgeries, as Tamsulosin can affect the eyes.
Can I take Tamsulosin with other prescription drugs?
Significant drug interactions with Tamsulosin include strong CYP3A4 inhibitors like ketoconazole, which can increase Tamsulosin levels. Caution is advised when used with PDE5 inhibitors, as both can lower blood pressure. Tamsulosin should not be combined with other alpha-blockers.
Can I take Tamsulosin with vitamins or supplements?
From all available and reliable information, there is no confirmed data on this. Please consult a doctor for personalized advice.
Can Tamsulosin be taken safely while pregnant?
Tamsulosin is not indicated for use in women, including during pregnancy. There is no adequate data on the developmental risk associated with Tamsulosin use in pregnant women. It is important for pregnant women to consult their doctor before taking any medication.
Can Tamsulosin be taken safely while breastfeeding?
Tamsulosin is not indicated for use in women, including those who are breastfeeding. There is no data on the presence of Tamsulosin in human milk or its effects on a breastfed infant. Consult a healthcare provider for advice on medication use while breastfeeding.
Is Tamsulosin safe for the elderly?
Elderly patients may be more sensitive to the effects of Tamsulosin, such as dizziness and fainting. It is important for elderly patients to be cautious when standing up quickly and to consult their doctor if they experience severe side effects. Regular monitoring by a healthcare provider is recommended.
Is it safe to exercise while taking Tamsulosin?
Tamsulosin may cause dizziness or lightheadedness, which could affect your ability to exercise safely. It is important to understand how the medication affects you before engaging in physical activities. Consult your doctor if you have concerns about exercising while taking Tamsulosin.
Is it safe to drink alcohol while taking Tamsulosin?
Drinking alcohol can increase the risk of side effects such as dizziness or fainting when taking Tamsulosin. It is advisable to limit alcohol consumption while on this medication to avoid these potential effects.
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