Etoricoxib + Paracetamol
Find more information about this combination medication at the webpages for etoricoxib and paracetamol
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Drug Status
Government Approvals
UK(BNF)
WHO Essential Medicine
YES
Known Teratogen
No
Pharmaceutical Class
None
Controlled Drug Substance
NO
Summary
Etoricoxib is used to relieve pain and inflammation, which refers to swelling and redness, in conditions like arthritis and gout, which is a form of arthritis characterized by severe pain in the joints. Paracetamol is commonly used to reduce fever and relieve mild to moderate pain, such as headaches, muscle aches, and toothaches. Both are used to manage pain, but Etoricoxib is specifically effective for inflammatory conditions, while Paracetamol is often used for general pain relief and fever reduction.
Etoricoxib works by blocking an enzyme called COX-2, which is responsible for producing substances that cause inflammation and pain. Paracetamol works by inhibiting the production of prostaglandins, which are chemicals in the brain that signal pain and cause fever. Both medicines relieve pain, but Etoricoxib targets inflammation, while Paracetamol is more focused on pain relief and fever reduction.
Etoricoxib is usually taken once a day, with the typical dose ranging from 60 to 120 milligrams, depending on the condition being treated. Paracetamol is often taken every 4 to 6 hours, with a usual dose of 500 to 1000 milligrams per dose, not exceeding 4000 milligrams in a day. Both medications are taken orally, which means by mouth, and should be used as directed by a healthcare professional.
Etoricoxib can cause side effects like stomach pain, diarrhea, and swelling of the legs or feet. Significant adverse effects may include increased risk of heart attack or stroke, and stomach ulcers. Paracetamol generally has fewer side effects, but in rare cases, it can cause skin rashes or liver damage if taken in high doses. Both medicines should be used as directed to minimize risks.
Etoricoxib can increase the risk of heart attack and stroke, especially in people with existing heart conditions. It should be used with caution in people with high blood pressure or heart disease. Paracetamol is generally safer for the heart but can cause liver damage if taken in high doses or with alcohol. Both medicines can cause stomach issues, so they should be taken with food or milk to reduce irritation.
Indications and Purpose
How does combination of Etoricoxib and Paracetamol work?
Etoricoxib and Paracetamol are both used to relieve pain, but they work in different ways. Etoricoxib is a type of medicine called a non-steroidal anti-inflammatory drug (NSAID), which reduces pain and inflammation by blocking an enzyme called COX-2, which is involved in the production of substances called prostaglandins that cause inflammation and pain. Paracetamol, on the other hand, is an analgesic, which means it relieves pain, and an antipyretic, which means it reduces fever. It works by blocking the production of prostaglandins in the brain, which helps to reduce pain and lower fever. Both medicines share the common attribute of relieving pain, but they do so through different mechanisms. Etoricoxib is more focused on reducing inflammation, while Paracetamol is often used for mild to moderate pain and fever without significant anti-inflammatory effects.
How effective is combination of Etoricoxib and Paracetamol?
Etoricoxib and Paracetamol are both effective pain relievers, but they work in different ways. Etoricoxib is a type of non-steroidal anti-inflammatory drug, which means it reduces inflammation and pain by blocking certain enzymes in the body. It's often used for conditions like arthritis. Paracetamol, on the other hand, is an analgesic, which means it relieves pain and reduces fever, but it doesn't reduce inflammation. It's commonly used for headaches and minor aches. Both medicines are effective in managing pain, but they have unique attributes. Etoricoxib is particularly useful for inflammatory pain, while Paracetamol is often preferred for its fever-reducing properties. They share the common attribute of being pain relievers, making them useful for a variety of conditions. However, they should be used as directed by a healthcare professional to avoid potential side effects.
Directions for Use
What is the usual dose of combination of Etoricoxib and Paracetamol?
Etoricoxib is usually taken once a day, with the typical dose ranging from 60 to 120 milligrams, depending on the condition being treated. It is a type of nonsteroidal anti-inflammatory drug, which means it helps reduce inflammation and pain. Paracetamol, on the other hand, is often taken every 4 to 6 hours, with a usual dose of 500 to 1000 milligrams per dose, not exceeding 4000 milligrams in a day. It is an analgesic, which means it helps relieve pain, and an antipyretic, which means it reduces fever. Both medicines are used to manage pain, but they work in different ways. Etoricoxib targets inflammation, while Paracetamol is more focused on pain relief and fever reduction. They are often used together to provide a more comprehensive approach to pain management.
How does one take combination of Etoricoxib and Paracetamol?
Etoricoxib, which is a type of non-steroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation, can be taken with or without food. However, taking it with food may help reduce stomach upset. Paracetamol, which is a pain reliever and fever reducer, can also be taken with or without food. There are no specific food restrictions for either medication, but it's important to follow the dosage instructions provided by your healthcare provider. Both Etoricoxib and Paracetamol are used to manage pain, but they work in different ways. Etoricoxib reduces inflammation, while Paracetamol primarily reduces pain and fever. It's important not to exceed the recommended dose for either medication to avoid potential side effects. Always consult with a healthcare professional before combining these medications or if you have any concerns about their use.
For how long is combination of Etoricoxib and Paracetamol taken?
Etoricoxib is typically used for short-term relief of pain and inflammation, which refers to swelling, in conditions like arthritis, which is a disease causing painful inflammation and stiffness of the joints. The duration of use depends on the condition being treated and the doctor's advice. Paracetamol, on the other hand, is often used for short-term relief of mild to moderate pain and fever, which is an elevated body temperature. It can be used for longer periods under medical supervision. Both medicines are used to relieve pain, but Etoricoxib is specifically for inflammation-related pain, while Paracetamol is more general. They both should be used as directed by a healthcare professional to avoid side effects, which are unwanted reactions to a drug. Always consult a doctor for the appropriate duration of use for your specific condition.
How long does it take for combination of Etoricoxib and Paracetamol to work?
The time it takes for a combination medicine to start working depends on the individual medicines involved. For example, if the combination includes ibuprofen, which is a pain reliever and anti-inflammatory, it typically starts working within 20 to 30 minutes. If the combination includes paracetamol, which is another pain reliever, it usually begins to work within 30 to 60 minutes. Both medicines are used to relieve pain and reduce fever, which means they share these common attributes. However, ibuprofen also reduces inflammation, which is swelling and redness, while paracetamol does not. When combined, these medicines can provide a broader range of relief, addressing both pain and inflammation more effectively. Always follow the dosage instructions provided by a healthcare professional to ensure safe and effective use.
Warnings and Precautions
Are there harms and risks from taking combination of Etoricoxib and Paracetamol?
Etoricoxib, which is a type of non-steroidal anti-inflammatory drug (NSAID), can cause side effects like stomach pain, diarrhea, and swelling of the legs or feet. Significant adverse effects may include increased risk of heart attack or stroke, and stomach ulcers. Paracetamol, which is a pain reliever and fever reducer, generally has fewer side effects, but in rare cases, it can cause skin rashes or liver damage if taken in high doses. Both Etoricoxib and Paracetamol are used to relieve pain, but they work differently. Etoricoxib reduces inflammation, which is the body's response to injury or infection, while Paracetamol does not. They share the common attribute of being pain relievers, but Etoricoxib has more potential for serious side effects compared to Paracetamol. It's important to use both medications as directed to minimize risks.
Can I take combination of Etoricoxib and Paracetamol with other prescription drugs?
Etoricoxib, which is a non-steroidal anti-inflammatory drug (NSAID) used to reduce pain and inflammation, can interact with other medications. It may increase the risk of stomach ulcers when taken with other NSAIDs or aspirin. It can also affect blood pressure, so caution is needed if taken with blood pressure medications. Paracetamol, which is a pain reliever and fever reducer, is generally considered safe but can cause liver damage if taken in high doses or with alcohol. Both Etoricoxib and Paracetamol can be used to manage pain, but they work differently. Etoricoxib reduces inflammation, while Paracetamol does not. They can be taken together for enhanced pain relief, but it is important to follow dosage recommendations to avoid side effects. Always consult a healthcare provider before combining these medications with others to ensure safety.
Can I take combination of Etoricoxib and Paracetamol if I am pregnant?
Etoricoxib, which is a type of non-steroidal anti-inflammatory drug (NSAID), is generally not recommended during pregnancy. This is because NSAIDs can affect the baby's heart and blood flow, especially if taken in the later stages of pregnancy. Paracetamol, which is a pain reliever and fever reducer, is considered safer during pregnancy when used at the recommended doses. It is often the preferred choice for managing pain and fever in pregnant women. Both Etoricoxib and Paracetamol are used to relieve pain, but they work in different ways. Etoricoxib reduces inflammation, which is the body's response to injury or infection, while Paracetamol does not have anti-inflammatory properties. Despite their differences, both medications should be used with caution during pregnancy, and it is important to consult a healthcare provider before taking any medication while pregnant.
Can I take combination of Etoricoxib and Paracetamol while breastfeeding?
Etoricoxib, which is a type of non-steroidal anti-inflammatory drug (NSAID), is not well-studied for use during breastfeeding. It is generally advised to avoid it due to the lack of data on its safety for nursing infants. Paracetamol, which is also known as acetaminophen, is considered safe for use during breastfeeding. It is commonly used to relieve pain and reduce fever, and only small amounts pass into breast milk, posing minimal risk to the infant. Both Etoricoxib and Paracetamol are used to manage pain, but they work differently. Etoricoxib reduces inflammation, which is the body's response to injury or infection, while Paracetamol primarily reduces pain and fever. When considering medication during breastfeeding, Paracetamol is preferred due to its established safety profile. Always consult a healthcare provider before taking any medication while breastfeeding to ensure the safety of both mother and child.
Who should avoid taking combination of Etoricoxib and Paracetamol?
Etoricoxib, which is a type of non-steroidal anti-inflammatory drug (NSAID), can increase the risk of heart attack and stroke, especially in people with existing heart conditions. It should be used with caution in people with high blood pressure, heart disease, or a history of stroke. Paracetamol, which is a pain reliever and fever reducer, is generally safer for the heart but can cause liver damage if taken in high doses or with alcohol. Both medicines can cause stomach issues, so they should be taken with food or milk to reduce irritation. People with liver or kidney problems should be cautious with both drugs. It's important to follow the recommended dosage and consult a healthcare provider if you have any pre-existing conditions or are taking other medications.
