Diclofenac + Metaxalone
Find more information about this combination medication at the webpages for Diclofenac and Metaxalone
Advisory
- इस दवा में 2 दवाओं Diclofenac और Metaxalone का संयोजन है।
- इनमें से प्रत्येक दवा एक अलग बीमारी या लक्षण का इलाज करती है।
- विभिन्न बीमारियों का अलग-अलग दवाओं से इलाज करने से डॉक्टरों को प्रत्येक दवा की खुराक को अलग-अलग समायोजित करने की सुविधा मिलती है। इससे ओवरमेडिकेशन या अंडरमेडिकेशन से बचा जा सकता है।
- अधिकांश डॉक्टर संयोजन फॉर्म का उपयोग करने से पहले यह सुनिश्चित करने की सलाह देते हैं कि प्रत्येक व्यक्तिगत दवा सुरक्षित और प्रभावी है।
Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
None
Controlled Drug Substance
NO
Summary
Diclofenac is used to relieve pain and inflammation, which is swelling and redness, in conditions like arthritis, which is a disease causing painful inflammation and stiffness of the joints. Metaxalone is used to relieve muscle pain and spasms, which are sudden, involuntary muscle contractions, often associated with acute musculoskeletal conditions, which are conditions affecting muscles, bones, and joints. Both medicines are used to manage pain, but Diclofenac targets inflammation while Metaxalone focuses on muscle relaxation.
Diclofenac works by blocking substances in the body that cause inflammation, which is swelling and redness. It is a nonsteroidal anti-inflammatory drug, which means it reduces inflammation and pain. Metaxalone works by relaxing the muscles, though its exact mechanism is not fully understood. It acts on the central nervous system, which is the brain and spinal cord, to relieve muscle spasms. Both medicines aim to reduce discomfort and improve mobility, but they achieve this through different mechanisms.
The usual adult daily dose for Diclofenac is typically 100 to 150 milligrams per day, divided into two or three doses. It is taken orally, which means by mouth. Metaxalone is usually taken as 800 milligrams three to four times a day, also orally. Both medicines should be taken with food to reduce the risk of stomach upset. It's important to follow the dosage instructions provided by your healthcare provider or the medicine's packaging.
Diclofenac can cause side effects like stomach pain, heartburn, and nausea. Significant adverse effects can include an increased risk of heart attack or stroke, and stomach ulcers. Metaxalone often leads to drowsiness, dizziness, and headache. Serious side effects may include liver damage and allergic reactions. Both medicines can cause dizziness and headache, which are shared side effects. It's important to use these medications under medical supervision to manage their side effects effectively.
Diclofenac can increase the risk of heart attack or stroke, especially if used long-term or in people with heart disease. It can also cause stomach ulcers and bleeding. Metaxalone can cause drowsiness and dizziness, so it should be used carefully in people who need to be alert. It can also affect liver function, so people with liver disease should avoid it. Both drugs can cause allergic reactions and should be used with caution in people with kidney problems. Always consult a healthcare provider before starting these medications.
Indications and Purpose
How does combination of Diclofenac and Metaxalone work?
Diclofenac is a nonsteroidal anti-inflammatory drug, which means it reduces inflammation and pain in the body. It works by blocking the production of certain chemicals called prostaglandins, which are involved in causing inflammation and pain. Metaxalone, on the other hand, is a muscle relaxant, which means it helps relieve muscle spasms. It works by acting on the central nervous system, which is the brain and spinal cord, to relax muscles. Both Diclofenac and Metaxalone are used to relieve pain, but they do so in different ways. Diclofenac targets inflammation, while Metaxalone focuses on muscle relaxation. They share the common goal of reducing discomfort and improving mobility, but they achieve this through different mechanisms. Diclofenac is often used for conditions like arthritis, while Metaxalone is used for muscle-related pain.
How effective is combination of Diclofenac and Metaxalone?
Diclofenac is a nonsteroidal anti-inflammatory drug, which means it helps reduce inflammation and pain in the body. It is often used to treat conditions like arthritis, which refers to joint inflammation, and other types of pain. Evidence shows that Diclofenac effectively reduces pain and swelling, making it easier for people to move and perform daily activities. Metaxalone is a muscle relaxant, which means it helps relieve muscle spasms and discomfort. It is typically used for short-term relief of muscle pain and is often prescribed alongside rest and physical therapy. Studies indicate that Metaxalone effectively reduces muscle tension and pain, improving mobility. Both Diclofenac and Metaxalone share the common attribute of pain relief, but they work in different ways. Diclofenac targets inflammation, while Metaxalone focuses on relaxing muscles. Together, they can provide comprehensive pain management for various conditions.
Directions for Use
What is the usual dose of combination of Diclofenac and Metaxalone?
The usual adult daily dose for Diclofenac, which is a nonsteroidal anti-inflammatory drug used to reduce inflammation and pain, is typically 100 to 150 milligrams per day, divided into two or three doses. Metaxalone, which is a muscle relaxant used to relieve muscle pain and discomfort, is usually taken as 800 milligrams three to four times a day. Diclofenac is unique in its ability to reduce inflammation, which is swelling and redness in the body, while Metaxalone is unique in its ability to relax muscles. Both medicines are used to relieve pain, but they work in different ways. Diclofenac works by reducing substances in the body that cause pain and inflammation, while Metaxalone works by blocking nerve impulses, which are signals that cause muscles to contract. Both medicines should be taken with food to reduce the risk of stomach upset.
How does one take combination of Diclofenac and Metaxalone?
Diclofenac, which is a nonsteroidal anti-inflammatory drug used to relieve pain and inflammation, can be taken with or without food. However, taking it with food or milk may help reduce stomach upset. It's important to avoid alcohol while taking Diclofenac, as it can increase the risk of stomach bleeding. Metaxalone, which is a muscle relaxant used to relieve muscle pain and discomfort, should be taken with or without food, but taking it with food may help improve absorption and reduce stomach upset. There are no specific food restrictions for Metaxalone, but alcohol should be avoided as it can enhance drowsiness. Both medicines share the common attribute of potentially causing stomach upset, so taking them with food might be beneficial. Additionally, both should be used cautiously with alcohol to prevent increased side effects.
For how long is combination of Diclofenac and Metaxalone taken?
Diclofenac, which is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation, is typically used for short-term treatment. The duration can vary depending on the condition being treated, but it is often used for a few days to a couple of weeks. Metaxalone, which is a muscle relaxant used to relieve muscle pain and spasms, is also generally used for short-term relief, often for a few weeks. Both medicines are used to manage pain, but they work in different ways. Diclofenac reduces inflammation, while Metaxalone relaxes muscles. They share the common attribute of being used for short-term pain relief. However, Diclofenac is more focused on reducing inflammation, whereas Metaxalone is specifically for muscle-related discomfort.
How long does it take for combination of Diclofenac and Metaxalone to work?
The time it takes for a combination medicine to start working depends on the individual medicines it contains. For example, if the combination includes ibuprofen, which is a pain reliever and anti-inflammatory drug, it typically starts working within 20 to 30 minutes. If it also contains acetaminophen, which is another pain reliever, it usually begins to work within 30 to 60 minutes. Both medicines are used to relieve pain and reduce fever, which means they share these common attributes. However, ibuprofen also reduces inflammation, which is swelling and redness, while acetaminophen does not. When combined, these medicines can provide a broader range of pain relief and fever reduction, often working together to enhance their effects. Always follow the dosage instructions provided by your healthcare provider or the medicine's packaging.
Warnings and Precautions
Are there harms and risks from taking combination of Diclofenac and Metaxalone?
Diclofenac, which is a nonsteroidal anti-inflammatory drug (NSAID), commonly causes side effects like stomach pain, heartburn, and nausea. Significant adverse effects can include increased risk of heart attack or stroke, and stomach ulcers. Metaxalone, which is a muscle relaxant, often leads to drowsiness, dizziness, and headache. Serious side effects may include liver damage and allergic reactions. Both Diclofenac and Metaxalone can cause dizziness and headache, which are shared side effects. However, Diclofenac is unique in its potential to cause heart-related issues and stomach problems, while Metaxalone is more likely to cause drowsiness and liver-related issues. It's important to use these medications under medical supervision to manage their side effects effectively.
Can I take combination of Diclofenac and Metaxalone with other prescription drugs?
Diclofenac, which is a nonsteroidal anti-inflammatory drug (NSAID), is used to relieve pain and inflammation. It can interact with other medications like blood thinners, which are drugs that prevent blood clots, increasing the risk of bleeding. It may also interact with other NSAIDs, leading to increased side effects like stomach ulcers. Metaxalone, which is a muscle relaxant, is used to relieve muscle pain and discomfort. It can interact with central nervous system depressants, which are drugs that slow down brain activity, such as alcohol or sedatives, leading to increased drowsiness or dizziness. Both Diclofenac and Metaxalone can cause liver damage if taken with other drugs that affect the liver. They should be used cautiously in people with liver problems. It's important to consult a healthcare provider before combining these medications with others.
Can I take combination of Diclofenac and Metaxalone if I am pregnant?
Diclofenac is a nonsteroidal anti-inflammatory drug, which is a type of medicine used to reduce pain and inflammation. During pregnancy, especially in the later stages, it is generally advised to avoid Diclofenac as it may affect the baby's heart and blood flow. Metaxalone is a muscle relaxant, which is a type of medicine used to relieve muscle pain and discomfort. The safety of Metaxalone during pregnancy is not well established, and it should be used only if clearly needed and prescribed by a doctor. Both Diclofenac and Metaxalone should be used with caution during pregnancy. They share the common attribute of being used to relieve pain, but they work in different ways. Diclofenac targets inflammation, while Metaxalone focuses on muscle relaxation. It is important to consult a healthcare provider before using either medication during pregnancy to ensure the safety of both the mother and the baby.
Can I take combination of Diclofenac and Metaxalone while breastfeeding?
Diclofenac, which is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation, is generally considered safe during breastfeeding. It passes into breast milk in small amounts, and no harmful effects on the nursing infant have been reported. However, it is always best to use the lowest effective dose for the shortest duration. Metaxalone, which is a muscle relaxant used to relieve muscle pain and discomfort, has limited data available regarding its safety during breastfeeding. It is not known how much Metaxalone passes into breast milk or its effects on a nursing infant. Therefore, caution is advised, and it is important to consult a healthcare provider before use. Both medications share the common attribute of being used to relieve pain, but they work in different ways. Diclofenac reduces inflammation, while Metaxalone relaxes muscles. Always consult a healthcare provider for personalized advice.
Who should avoid taking combination of Diclofenac and Metaxalone?
Diclofenac, which is a nonsteroidal anti-inflammatory drug (NSAID), can increase the risk of heart attack or stroke, especially if used long-term or in people with heart disease. It can also cause stomach ulcers and bleeding. People with a history of heart disease, stroke, or stomach ulcers should be cautious. Metaxalone, which is a muscle relaxant, can cause drowsiness and dizziness. It should be used carefully in people who need to be alert, like those driving or operating machinery. It can also affect liver function, so people with liver disease should avoid it. Both drugs can cause allergic reactions, so people with known allergies to these medications should not use them. They should also be used with caution in people with kidney problems. Always consult a healthcare provider before starting these medications to ensure they are safe for you.