Dapoxetine + Sildenafil

Find more information about this combination medication at the webpages for Dapoxetine and Sildenafil

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Advisory

  • इस दवा में 2 दवाओं Dapoxetine और Sildenafil का संयोजन है।
  • इनमें से प्रत्येक दवा एक अलग बीमारी या लक्षण का इलाज करती है।
  • विभिन्न बीमारियों का अलग-अलग दवाओं से इलाज करने से डॉक्टरों को प्रत्येक दवा की खुराक को अलग-अलग समायोजित करने की सुविधा मिलती है। इससे ओवरमेडिकेशन या अंडरमेडिकेशन से बचा जा सकता है।
  • अधिकांश डॉक्टर संयोजन फॉर्म का उपयोग करने से पहले यह सुनिश्चित करने की सलाह देते हैं कि प्रत्येक व्यक्तिगत दवा सुरक्षित और प्रभावी है।

Drug Status

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Government Approvals

UK(BNF)

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WHO Essential Medicine

NO

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Known Teratogen

NO

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Pharmaceutical Class

None

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Controlled Drug Substance

NO

Summary

  • Dapoxetine is used to treat premature ejaculation, which is when ejaculation happens sooner than desired during sexual activity. Sildenafil is used to treat erectile dysfunction, which is the inability to achieve or maintain an erection suitable for sexual activity. Both medications aim to improve sexual function but target different issues.

  • Dapoxetine works by increasing serotonin levels in the brain, which helps delay ejaculation. Serotonin is a chemical that affects mood and behavior. Sildenafil works by increasing blood flow to the penis, helping to achieve and maintain an erection. It does this by blocking an enzyme called phosphodiesterase type 5, which regulates blood flow.

  • Dapoxetine is usually taken as a single dose of 30 mg to 60 mg, 1 to 3 hours before sexual activity. Sildenafil is typically taken as a single dose of 50 mg, about 1 hour before sexual activity, but can be adjusted to 25 mg or 100 mg. Both medications are taken orally and are used as needed, not for daily use.

  • Dapoxetine can cause side effects like nausea, dizziness, and headache. Sildenafil may cause headaches, flushing, and indigestion. Both medications can cause dizziness and headaches, and they share the risk of causing fainting, especially when combined with alcohol or other medications.

  • Dapoxetine should not be used by people with heart problems, as it can cause dizziness and fainting. Sildenafil should not be used with nitrates, which are medications for chest pain, as it can cause a dangerous drop in blood pressure. Both should be used under medical supervision, and alcohol should be avoided to reduce the risk of side effects.

Indications and Purpose

How does combination of Dapoxetine and Sildenafil work?

Dapoxetine is a medication used to treat premature ejaculation, which is a condition where ejaculation happens sooner than desired during sexual activity. It works by increasing the levels of serotonin, which is a chemical in the brain that helps to delay ejaculation. This action helps to improve control over ejaculation and increase the time it takes to ejaculate. Sildenafil is used to treat erectile dysfunction, which is the inability to get or keep an erection firm enough for sexual intercourse. It works by increasing blood flow to the penis, which helps to achieve and maintain an erection. Sildenafil does this by blocking an enzyme called phosphodiesterase type 5, which is responsible for regulating blood flow in the penis. Both Dapoxetine and Sildenafil are used to improve sexual function, but they work in different ways. Dapoxetine affects brain chemicals, while Sildenafil affects blood flow.

How effective is combination of Dapoxetine and Sildenafil?

Dapoxetine is a medication used to treat premature ejaculation, which is a condition where ejaculation happens sooner than desired during sexual activity. It works by increasing serotonin levels in the brain, which helps delay ejaculation. Sildenafil, on the other hand, is used to treat erectile dysfunction, which is the inability to get or maintain an erection. It works by increasing blood flow to the penis. Both Dapoxetine and Sildenafil are taken orally and are used to improve sexual performance. They share the common attribute of enhancing sexual experience, but they target different issues. Dapoxetine focuses on delaying ejaculation, while Sildenafil helps achieve and maintain an erection. Both medications have been proven effective through clinical studies, showing significant improvement in their respective conditions. However, they should be used under medical supervision to ensure safety and effectiveness.

How does one know if combination of Dapoxetine and Sildenafil is working?

The benefit of Dapoxetine, which is used to treat premature ejaculation, is measured by its ability to increase the time it takes to ejaculate and improve control over ejaculation. It is assessed through patient-reported outcomes and clinical studies that track these improvements. On the other hand, Sildenafil, which is used to treat erectile dysfunction, is measured by its ability to help achieve and maintain an erection sufficient for sexual activity. This is assessed through patient feedback and clinical trials that evaluate erectile function. Both Dapoxetine and Sildenafil share the common attribute of improving sexual function, but they target different issues. Dapoxetine focuses on ejaculation control, while Sildenafil focuses on erectile function. Both are taken orally and are assessed through similar methods, such as patient satisfaction and clinical effectiveness. However, they work through different mechanisms in the body to achieve their specific benefits.

Directions for Use

What is the usual dose of combination of Dapoxetine and Sildenafil?

Dapoxetine, which is used to treat premature ejaculation, is usually taken as a single dose of 30 mg to 60 mg about 1 to 3 hours before sexual activity. It is not meant for daily use and should only be taken when needed. Sildenafil, which is used to treat erectile dysfunction, is typically taken as a single dose of 50 mg about 1 hour before sexual activity, but it can be adjusted to 25 mg or 100 mg based on effectiveness and tolerance. Both medicines are taken orally and work by affecting chemicals in the brain or blood vessels to improve sexual function. However, Dapoxetine is unique in its action on serotonin levels, which are chemicals in the brain that affect mood and behavior, while Sildenafil works by increasing blood flow to the penis.

How does one take combination of Dapoxetine and Sildenafil?

Dapoxetine, which is used to treat premature ejaculation, can be taken with or without food. It is important to take it with a full glass of water to help it work properly. Avoid alcohol while taking Dapoxetine, as it can increase the risk of side effects like dizziness. Sildenafil, which is used to treat erectile dysfunction, can also be taken with or without food. However, it may take longer to work if taken with a high-fat meal. Avoid grapefruit and grapefruit juice while taking Sildenafil, as they can affect how the medicine works. Both Dapoxetine and Sildenafil should be taken as prescribed by a healthcare provider. They share the common attribute of being taken orally and having potential interactions with alcohol. Always follow your healthcare provider's instructions and discuss any concerns or questions you have about these medications.

For how long is combination of Dapoxetine and Sildenafil taken?

Dapoxetine is typically used as needed, about 1 to 3 hours before sexual activity, to treat premature ejaculation, which is a condition where ejaculation happens sooner than desired. Sildenafil is also used as needed, about 30 minutes to 1 hour before sexual activity, to treat erectile dysfunction, which is the inability to get or keep an erection firm enough for sex. Both medicines are taken orally and are not intended for daily use. They share the common attribute of being used to improve sexual performance, but they target different issues. Dapoxetine works by increasing serotonin levels, which helps delay ejaculation, while Sildenafil increases blood flow to the penis to help achieve an erection. Both should be used under medical guidance to ensure safety and effectiveness.

How long does it take for combination of Dapoxetine and Sildenafil to work?

The time it takes for a combination medicine to start working depends on the individual medicines involved. For example, if the combination includes ibuprofen, which is a pain reliever and anti-inflammatory drug, it typically starts working within 20 to 30 minutes. If the combination includes paracetamol, which is another pain reliever, it usually begins to work within 30 to 60 minutes. Both medicines are used to relieve pain and reduce fever, which means they share these common attributes. However, ibuprofen also reduces inflammation, which is swelling and redness, while paracetamol does not. When combined, these medicines can provide a broader range of relief, addressing both pain and inflammation more effectively. Always follow the dosage instructions provided by a healthcare professional to ensure safe and effective use.

How does one store combination of Dapoxetine and Sildenafil?

Dapoxetine, which is used to treat premature ejaculation, and Sildenafil, which is used to treat erectile dysfunction, do not require refrigeration. Both medicines should be stored at room temperature, which means keeping them in a place that is not too hot or too cold, ideally between 68°F and 77°F (20°C and 25°C). They should be kept away from moisture and direct sunlight, so a dry, dark place like a cupboard is ideal. A unique attribute of Dapoxetine is that it is a short-acting selective serotonin reuptake inhibitor, which means it works by increasing serotonin levels in the brain to delay ejaculation. Sildenafil, on the other hand, is a phosphodiesterase type 5 inhibitor, which means it helps increase blood flow to the penis to help maintain an erection. Both medicines should be kept out of reach of children and should not be used past their expiration date.

Warnings and Precautions

Are there harms and risks from taking combination of Dapoxetine and Sildenafil?

Dapoxetine, which is used to treat premature ejaculation, can cause side effects like nausea, dizziness, and headache. Some significant adverse effects include mood changes and fainting. Sildenafil, which is used to treat erectile dysfunction, may cause headaches, flushing, and indigestion. Serious adverse effects can include sudden vision or hearing loss. Both Dapoxetine and Sildenafil can cause headaches and dizziness. They also share the risk of causing fainting, especially when combined with alcohol or other medications. However, Dapoxetine is unique in its potential to affect mood, while Sildenafil is known for its effects on vision and hearing. It's important to use these medications under medical supervision to manage these side effects and avoid potential interactions with other drugs.

Can I take combination of Dapoxetine and Sildenafil with other prescription drugs?

Dapoxetine, which is used to treat premature ejaculation, and Sildenafil, which is used to treat erectile dysfunction, both have significant drug interactions. Both drugs can interact with nitrates, which are medications used to treat chest pain, leading to a dangerous drop in blood pressure. They also interact with alpha-blockers, which are used to treat high blood pressure and prostate problems, potentially causing dizziness or fainting. Dapoxetine is unique in that it can interact with certain antidepressants, which can increase the risk of serotonin syndrome, a condition that can cause confusion, rapid heart rate, and high blood pressure. Sildenafil, on the other hand, can interact with certain antifungal and antibiotic medications, which can increase the levels of Sildenafil in the blood, leading to increased side effects. Both medications should be used with caution in people with heart problems, and it is important to consult a healthcare provider before combining them with other medications.

Can I take combination of Dapoxetine and Sildenafil if I am pregnant?

Dapoxetine, which is used to treat premature ejaculation, is not recommended during pregnancy. There is limited information on its effects on pregnant women, so it is best to avoid it unless absolutely necessary. Sildenafil, which is used to treat erectile dysfunction and sometimes pulmonary hypertension, is also not recommended during pregnancy unless the benefits outweigh the risks. It can affect blood flow, which might impact the developing baby. Both Dapoxetine and Sildenafil are not typically used during pregnancy, and their safety profiles are not well-established for pregnant women. They share the common attribute of being used for conditions related to sexual health, but they work differently. Dapoxetine affects serotonin levels, which are chemicals in the brain, while Sildenafil affects blood flow. Always consult a healthcare provider before using these medications during pregnancy.

Can I take combination of Dapoxetine and Sildenafil while breastfeeding?

Dapoxetine, which is used to treat premature ejaculation, has limited information available regarding its safety during breastfeeding. It is not clear how much of the drug passes into breast milk or what effects it might have on a nursing infant. Therefore, caution is advised, and it is best to consult a healthcare provider before use. Sildenafil, which is used to treat erectile dysfunction, also lacks specific data on its safety during breastfeeding. Like Dapoxetine, it is unknown how much Sildenafil is excreted in breast milk or its potential impact on a breastfed child. Consulting a healthcare provider is recommended. Both Dapoxetine and Sildenafil share the common concern of insufficient data on their safety during lactation. They both require medical consultation before use by breastfeeding mothers. However, they are used for different conditions, with Dapoxetine addressing premature ejaculation and Sildenafil treating erectile dysfunction.

Who should avoid taking combination of Dapoxetine and Sildenafil?

Dapoxetine, which is used to treat premature ejaculation, should not be used by people with heart problems, such as heart failure or a history of fainting. It can cause dizziness and fainting, especially when standing up quickly. Sildenafil, which is used to treat erectile dysfunction, should not be used by people taking nitrates, which are medications for chest pain, as it can cause a dangerous drop in blood pressure. Both Dapoxetine and Sildenafil can cause side effects like headaches and dizziness. They should not be used together without consulting a doctor, as this can increase the risk of side effects. People with liver or kidney problems should use these medications with caution. It's important to avoid alcohol when taking these drugs, as it can increase the risk of side effects like dizziness and fainting.