Dapoxetine
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Drug Status
Government Approvals
UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
None
Controlled Drug Substance
No
Dapoxetine
Summary
Dapoxetine is used to treat premature ejaculation, which is when ejaculation happens sooner than desired during sexual activity. This condition can cause distress and affect sexual satisfaction.
Dapoxetine works by increasing serotonin levels in the brain, which is a chemical that affects mood and behavior. This helps delay ejaculation and improves control over the timing.
The usual starting dose of Dapoxetine for adults is 30 mg, taken 1 to 3 hours before sexual activity. If well-tolerated but not effective, the dose may be increased to 60 mg. It is taken as needed, not more than once in 24 hours.
Common side effects of Dapoxetine include nausea, dizziness, and headaches, which are unwanted reactions to the medication. These effects are usually mild to moderate and affect more than 10% of users.
Dapoxetine can cause dizziness and fainting, especially when standing up quickly. It should not be used by individuals with heart problems or liver impairment. Always inform your doctor about your medical history and any medications you take.
Indications and Purpose
How does Dapoxetine work?
Dapoxetine works by increasing serotonin levels in the brain, which helps delay ejaculation. Serotonin is a chemical that affects mood and behavior. By enhancing serotonin activity, Dapoxetine helps improve control over ejaculation and increases the time to ejaculation during sexual activity. Think of it like adjusting the timing of a clock to slow down the process. This mechanism makes Dapoxetine effective for treating premature ejaculation, which is when ejaculation happens sooner than desired.
Is Dapoxetine effective?
Yes, Dapoxetine is effective for treating premature ejaculation, which is a condition where ejaculation happens sooner than desired during sexual activity. Clinical studies show that Dapoxetine significantly improves control over ejaculation and increases the time to ejaculation. It works by increasing serotonin levels in the brain, which helps delay ejaculation. Most users experience improved sexual satisfaction and reduced distress related to premature ejaculation. Always follow your doctor's instructions for the best results.
What is Dapoxetine?
Dapoxetine is a medication used to treat premature ejaculation, which is when ejaculation happens sooner than desired during sexual activity. It belongs to a class of drugs called selective serotonin reuptake inhibitors (SSRIs). Dapoxetine works by increasing serotonin levels in the brain, which helps delay ejaculation. It's taken as needed, 1 to 3 hours before sexual activity. Dapoxetine is not intended for daily use and should be used under the guidance of a healthcare provider.
Directions for Use
For how long do I take Dapoxetine?
Dapoxetine is used for short-term treatment of premature ejaculation, which is when ejaculation happens sooner than desired. It's taken as needed, 1 to 3 hours before sexual activity, and not more than once in 24 hours. The duration of use depends on your response to the medication and your doctor's advice. Always follow your doctor's instructions on how long to take Dapoxetine. They will guide you based on your specific health needs.
How do I dispose of Dapoxetine?
To dispose of Dapoxetine, take it to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of it properly to prevent harm to people or the environment. If a take-back program isn't available, you can throw it in the trash at home. First, remove it from its original container, mix it with something undesirable like used coffee grounds, seal the mixture in a plastic bag, and throw it away. Always keep medications out of reach of children.
How do I take Dapoxetine?
Take Dapoxetine as prescribed by your doctor. It's usually taken 1 to 3 hours before sexual activity, not more than once in 24 hours. Swallow the tablet whole with water, with or without food. Avoid crushing or chewing it. If you miss a dose, take it when you remember, but not if it's close to your next dose. Avoid alcohol, as it can increase side effects like dizziness. Always follow your doctor's specific instructions for taking Dapoxetine.
How long does it take for Dapoxetine to start working?
Dapoxetine starts working within 1 to 3 hours after taking it. This is why it's recommended to take it 1 to 3 hours before sexual activity. The full therapeutic effect is usually achieved within this time frame. Individual factors like metabolism and overall health can affect how quickly Dapoxetine works. Always take it as prescribed by your doctor for the best results. If you have concerns about how Dapoxetine is working, discuss them with your healthcare provider.
How should I store Dapoxetine?
Store Dapoxetine at room temperature, away from moisture and light. Keep it in its original packaging until you're ready to take it. Avoid storing it in humid places like bathrooms, as moisture can affect the medication's effectiveness. Always keep Dapoxetine out of reach of children to prevent accidental ingestion. Check the expiration date regularly and properly dispose of any unused or expired medication. If you have questions about storage, consult your pharmacist or doctor.
What is the usual dose of Dapoxetine?
The usual starting dose of Dapoxetine for adults is 30 mg, taken 1 to 3 hours before sexual activity. If the 30 mg dose is well-tolerated but not effective, your doctor may increase it to 60 mg. Dapoxetine is not intended for daily use and should not be taken more than once in 24 hours. There are no specific dose adjustments for children or the elderly, but elderly patients should be monitored closely. Always follow your doctor's dosing instructions.
Warnings and Precautions
Can Dapoxetine be taken safely while breastfeeding?
Dapoxetine is not recommended while breastfeeding. There is limited information on whether it passes into human breast milk. Animal studies suggest it may appear in milk, raising concerns about potential effects on a nursing infant. The impact on milk production is also unknown. If you're breastfeeding and need treatment for premature ejaculation, talk with your doctor. They can discuss safer medication options that allow you to nurse your baby safely.
Can Dapoxetine be taken safely while pregnant?
Dapoxetine is not recommended during pregnancy. There is limited evidence on its safety for pregnant women. Animal studies have not shown direct harm, but the effects on human pregnancy are not well-studied. If you are pregnant or planning to become pregnant, talk with your doctor. They can help determine the safest treatment options for your condition during pregnancy. Your doctor will create a plan that protects both you and your baby.
Can I take Dapoxetine with other prescription drugs?
Dapoxetine has several important drug interactions. It should not be used with MAO inhibitors, thioridazine, or other SSRIs, as these can increase the risk of serotonin syndrome, which is a potentially life-threatening condition. Combining Dapoxetine with certain medications like nitrates or alpha-blockers can cause severe drops in blood pressure. Always inform your doctor about all medications you take to avoid harmful interactions. Your doctor will help ensure Dapoxetine is safe and effective for you.
Does Dapoxetine have adverse effects?
Adverse effects are unwanted reactions to a medication. Dapoxetine can cause nausea, dizziness, and headaches, which are common adverse effects. These occur in more than 10% of users. Serious side effects include fainting and mood changes, which require immediate medical attention. If you experience any adverse effects, inform your doctor. They can help manage these effects and adjust your treatment if necessary. Always report new or worsening symptoms while taking Dapoxetine.
Does Dapoxetine have any safety warnings?
Yes, Dapoxetine has important safety warnings. It can cause dizziness and fainting, especially when standing up quickly. This is due to its effect on blood pressure. Not following these warnings can lead to falls or injuries. Dapoxetine should not be used by individuals with heart problems, as it can increase the risk of heart-related issues. Always inform your doctor about your medical history and any medications you take to ensure Dapoxetine is safe for you.
Is Dapoxetine addictive?
Dapoxetine is not considered addictive or habit-forming. It does not cause physical or psychological dependence. The medication works by affecting serotonin levels in the brain, which helps delay ejaculation. This mechanism does not lead to addiction. You won't experience cravings or withdrawal symptoms when stopping Dapoxetine. If you have concerns about medication dependence, discuss them with your doctor. They can provide reassurance and guidance on using Dapoxetine safely.
Is Dapoxetine safe for the elderly?
Elderly individuals may be more sensitive to the side effects of Dapoxetine, such as dizziness and fainting. These effects can increase the risk of falls and injuries. It's important for elderly users to be closely monitored by their doctor while taking Dapoxetine. The doctor may adjust the dose or suggest alternative treatments based on the individual's health status. Always discuss any concerns with your healthcare provider to ensure safe use of Dapoxetine.
Is it safe to drink alcohol while taking Dapoxetine?
It's best to avoid alcohol while taking Dapoxetine. Alcohol can increase the risk of side effects like dizziness and fainting, which are already possible with Dapoxetine. This combination can impair your ability to perform tasks that require alertness. If you choose to drink, limit your alcohol intake and be cautious of any symptoms like dizziness or lightheadedness. Talk with your doctor about alcohol use while taking Dapoxetine for personalized advice.
Is it safe to exercise while taking Dapoxetine?
Yes, you can exercise while taking Dapoxetine, but be cautious. This medication can cause dizziness or fainting, especially when standing up quickly. These symptoms might be more noticeable during physical activity. To exercise safely, stay hydrated and avoid sudden movements. If you feel dizzy or lightheaded, stop exercising and rest. Most people can maintain their regular exercise routine while taking Dapoxetine, but consult your doctor if you have concerns.
Is it safe to stop Dapoxetine?
Yes, it's generally safe to stop Dapoxetine, as it is used for short-term treatment of premature ejaculation. There are no withdrawal symptoms associated with stopping Dapoxetine. However, stopping the medication may result in the return of symptoms. Always talk with your doctor before stopping Dapoxetine. They can provide guidance on managing your condition and discuss alternative treatments if needed. Your doctor will help ensure any changes to your medication are safe and effective.
What are the most common side effects of Dapoxetine?
Side effects are unwanted reactions to a medication. Common side effects of Dapoxetine include nausea, dizziness, and headaches, affecting more than 10% of users. These side effects are usually mild to moderate. If you experience new symptoms after starting Dapoxetine, they might be temporary or unrelated to the medication. It's important to talk with your doctor before stopping any medication. They can help determine if the side effects are related to Dapoxetine and suggest appropriate management.
Who should avoid taking Dapoxetine?
Dapoxetine has important contraindications. Do not use it if you have heart problems, such as heart failure or a history of fainting. It's also contraindicated in those with liver impairment. Dapoxetine should not be used with certain medications like MAO inhibitors or thioridazine, as these can cause serious interactions. Always inform your doctor about your medical history and any medications you take to ensure Dapoxetine is safe for you. Your doctor will help determine if the benefits outweigh the risks.
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