Dapagliflozin + Vildagliptin
Find more information about this combination medication at the webpages for Dapagliflozin and Vildagliptin
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Advisory
- इस दवा में 2 दवाओं Dapagliflozin और Vildagliptin का संयोजन है।
- Dapagliflozin और Vildagliptin दोनों का उपयोग एक ही बीमारी या लक्षण के इलाज के लिए किया जाता है, लेकिन शरीर में अलग-अलग तरीके से काम करते हैं।
- अधिकांश डॉक्टर संयोजन रूप का उपयोग करने से पहले यह सुनिश्चित करने की सलाह देंगे कि प्रत्येक व्यक्तिगत दवा सुरक्षित और प्रभावी है।
Drug Status
Government Approvals
UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
None
Controlled Drug Substance
NO
Dapagliflozin + Vildagliptin
Summary
Dapagliflozin and Vildagliptin are both used to manage type 2 diabetes, which is a condition where the body does not use insulin properly, leading to high blood sugar levels. These medications help control blood sugar levels when diet and exercise alone are not enough. They are often used in combination with other diabetes medications to enhance their effects and prevent complications related to diabetes, such as heart disease and nerve damage.
Dapagliflozin works by helping the kidneys remove glucose, which is a type of sugar, from the bloodstream through urine. This helps lower blood sugar levels. Vildagliptin increases the levels of certain hormones that help the pancreas release more insulin, which is a hormone that lowers blood sugar, especially after meals. Both medications aim to improve blood sugar control but work through different mechanisms.
Dapagliflozin is usually taken as a 10 mg tablet once a day. It can be taken with or without food. Vildagliptin is typically taken as a 50 mg tablet twice a day, also with or without food. Both medications are taken orally and are part of a long-term diabetes management plan. It's important to follow a healthcare provider's guidance on how to take these medications.
Dapagliflozin can cause side effects like urinary tract infections, which are infections in any part of the urinary system, and increased urination. It may also lead to dehydration, which is a condition where the body loses more fluids than it takes in. Vildagliptin can cause headaches and dizziness, which is a feeling of being lightheaded or unsteady. Both medications can cause low blood sugar, especially when used with other diabetes medications.
Dapagliflozin is not recommended for people with severe kidney problems and should be used cautiously to avoid dehydration. Vildagliptin requires regular liver function tests due to the risk of liver problems. Both medications are not recommended during pregnancy or breastfeeding due to limited safety data. They are also not suitable for people with type 1 diabetes or diabetic ketoacidosis, which is a serious condition where the body produces high levels of blood acids.
Indications and Purpose
How does combination of Dapagliflozin and Vildagliptin work?
Dapagliflozin works by helping the kidneys remove glucose, which is a type of sugar, from the bloodstream through urine. This process helps lower blood sugar levels in people with type 2 diabetes. Vildagliptin, on the other hand, works by increasing the levels of certain hormones called incretins, which help the body produce more insulin, a hormone that lowers blood sugar, especially after meals. Both dapagliflozin and vildagliptin are used to manage blood sugar levels in people with type 2 diabetes. They help prevent complications related to high blood sugar, such as heart disease and nerve damage. However, they work in different ways: dapagliflozin targets the kidneys, while vildagliptin focuses on hormone regulation. Despite their differences, both medications aim to improve blood sugar control and overall health in diabetic patients.
How effective is combination of Dapagliflozin and Vildagliptin?
Dapagliflozin and Vildagliptin are both used to manage type 2 diabetes, which is a condition where the body does not use insulin properly. Dapagliflozin works by helping the kidneys remove glucose, which is a type of sugar, from the bloodstream through urine. This helps lower blood sugar levels. Vildagliptin, on the other hand, works by increasing the levels of certain hormones that help the pancreas release more insulin, which is a hormone that lowers blood sugar, especially after meals. Both medications help control blood sugar levels, which is crucial for preventing complications of diabetes. They are often used when diet and exercise alone are not enough to control blood sugar. While they work in different ways, both aim to improve blood sugar control and are often used in combination with other diabetes medications for better results.
Directions for Use
What is the usual dose of combination of Dapagliflozin and Vildagliptin?
Dapagliflozin is usually taken as a 10 mg tablet once a day. It helps lower blood sugar levels in adults with type 2 diabetes by making the kidneys remove more sugar from the body through urine. Vildagliptin is typically taken as a 50 mg tablet twice a day. It works by increasing the levels of certain hormones that help control blood sugar levels. Both medicines are used to manage type 2 diabetes, which is a condition where the body doesn't use insulin properly. They both help control blood sugar levels, but they work in different ways. Dapagliflozin works through the kidneys, while Vildagliptin works by affecting hormones. It's important to follow a doctor's advice on how to take these medicines.
How does one take combination of Dapagliflozin and Vildagliptin?
Dapagliflozin, which is a medicine used to lower blood sugar levels in people with type 2 diabetes, can be taken with or without food. There are no specific food restrictions associated with dapagliflozin, but it is important to maintain a balanced diet to manage diabetes effectively. Vildagliptin, which is another medicine used to control blood sugar levels in type 2 diabetes, can also be taken with or without food. Like dapagliflozin, there are no specific food restrictions for vildagliptin, but a healthy diet is recommended. Both medicines share the common goal of managing blood sugar levels, but they work in different ways. Dapagliflozin helps the kidneys remove glucose from the bloodstream, while vildagliptin increases the levels of hormones that help control blood sugar. Always follow your healthcare provider's instructions when taking these medications.
For how long is combination of Dapagliflozin and Vildagliptin taken?
Dapagliflozin and Vildagliptin are both used to manage type 2 diabetes, which is a condition where the body does not use insulin properly. The typical duration of use for both medicines is long-term, as they are part of ongoing diabetes management. Dapagliflozin works by helping the kidneys remove glucose from the bloodstream, which helps lower blood sugar levels. Vildagliptin, on the other hand, increases the levels of incretin hormones, which help control blood sugar by increasing insulin release. Both medicines are taken orally and are usually prescribed alongside lifestyle changes like diet and exercise. They share the common goal of controlling blood sugar levels but work through different mechanisms. It's important to follow a healthcare provider's guidance on how long to use these medications.
How long does it take for combination of Dapagliflozin and Vildagliptin to work?
The combination medicine typically starts working within 30 minutes to an hour. This is because it contains two active ingredients: ibuprofen and pseudoephedrine. Ibuprofen, which is a non-steroidal anti-inflammatory drug (NSAID), helps reduce pain and inflammation. It usually begins to relieve pain within 20 to 30 minutes after taking it. Pseudoephedrine, which is a decongestant, works by narrowing the blood vessels in the nasal passages to reduce swelling and congestion. It generally starts to work within 30 minutes. Both medicines are absorbed quickly into the bloodstream, which is why they start working relatively fast. However, the exact time can vary depending on individual factors like metabolism and whether the medicine is taken with food. Together, they provide relief from symptoms like pain, inflammation, and nasal congestion.
Warnings and Precautions
Are there harms and risks from taking combination of Dapagliflozin and Vildagliptin?
Dapagliflozin, which is a medication used to treat type 2 diabetes, commonly causes side effects like urinary tract infections, which are infections in any part of the urinary system, and increased urination. Significant adverse effects can include dehydration, which is a condition where the body loses more fluids than it takes in, and low blood pressure. Vildagliptin, another medication for type 2 diabetes, often causes side effects such as headaches and dizziness, which is a feeling of being lightheaded or unsteady. A significant adverse effect of Vildagliptin is liver dysfunction, which refers to the liver not working properly. Both medications help control blood sugar levels but work in different ways. Dapagliflozin works by helping the kidneys remove glucose from the bloodstream, while Vildagliptin increases the levels of hormones that stimulate insulin release. Both can cause low blood sugar, which is a condition where blood sugar levels drop too low.
Can I take combination of Dapagliflozin and Vildagliptin with other prescription drugs?
Dapagliflozin, which is a medication used to lower blood sugar in people with type 2 diabetes, can interact with diuretics, which are medications that help the body get rid of excess salt and water. This combination can increase the risk of dehydration, which means losing too much water from the body. Vildagliptin, which is another medication for type 2 diabetes, can interact with other diabetes medications, potentially leading to low blood sugar, which is also known as hypoglycemia. Both dapagliflozin and vildagliptin are used to manage blood sugar levels, but they work in different ways. Dapagliflozin helps the kidneys remove sugar from the body, while vildagliptin increases the levels of hormones that help control blood sugar. Both medications require careful monitoring when used with other drugs to avoid unwanted side effects.
Can I take combination of Dapagliflozin and Vildagliptin if I am pregnant?
Dapagliflozin, which is a medication used to treat type 2 diabetes by helping the kidneys remove glucose from the bloodstream, is not recommended during pregnancy. This is because there is limited information on its safety for pregnant women, and it may pose risks to the developing baby. Vildagliptin, which is another medication for type 2 diabetes that works by increasing the levels of insulin produced after meals, also lacks sufficient safety data for use during pregnancy. Both medications share the common attribute of being used to manage blood sugar levels in type 2 diabetes, but they work in different ways. The main shared concern is the lack of adequate studies on their safety during pregnancy, which means they should be used with caution and only if the potential benefits outweigh the risks.
Can I take combination of Dapagliflozin and Vildagliptin while breastfeeding?
Dapagliflozin, which is a medication used to lower blood sugar in adults with type 2 diabetes, is not recommended during breastfeeding. This is because there is limited information on whether it passes into breast milk and its potential effects on a nursing infant. Vildagliptin, which is another medication used to manage blood sugar levels in type 2 diabetes, also lacks sufficient data regarding its safety during breastfeeding. Both medications share the common concern of insufficient research on their effects on breastfed infants. However, they differ in their mechanisms of action; Dapagliflozin works by helping the kidneys remove glucose from the bloodstream, while Vildagliptin increases the levels of hormones that stimulate the pancreas to release insulin. Due to the lack of data, healthcare providers often recommend alternative treatments for breastfeeding mothers.
Who should avoid taking combination of Dapagliflozin and Vildagliptin?
Dapagliflozin, which is used to lower blood sugar in people with type 2 diabetes, can cause dehydration, which means losing too much water from the body. This can lead to dizziness or fainting. It may also increase the risk of urinary tract infections and genital infections. People with severe kidney problems should avoid it. Vildagliptin, which helps control blood sugar levels, can cause liver problems. Regular liver function tests are recommended. It may also cause joint pain and should be used cautiously in people with heart failure. Both medicines can cause low blood sugar, especially when used with other diabetes medications. They are not recommended for people with type 1 diabetes or diabetic ketoacidosis, which is a serious condition where the body produces high levels of blood acids. Always consult a healthcare provider before starting these medications.
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