Sameral 400 Tablet is a medicine containing S-adenosyl methionine (SAMe), which synthetic version of a natural chemical in the body Often used in alternative medicine, it's recognized for potentially aiding in osteoarthritis treatment However, its effectiveness in treating various conditions, from depression to liver disease.

SAMe is commonly employed in alternative medicine to address osteoarthritis symptoms and has been explored for conditions like depression, liver disease-related symptoms, and itching.

SAMe is believed to impact serotonin levels, influencing mood and addressing symptoms in conditions like depression Additionally, it's considered for its potential in managing osteoarthritis.

If considering SAMe, consult your healthcare provider for guidance Typically taken on an empty stomach, SAMe should be used as directed, and its use for specific conditions may vary.

Avoid SAMe if you have bipolar depression, anxiety disorder, or are on antidepressant medications Interaction risks exist with medications like MAO inhibitors and stimulants, potentially leading to serotonin syndrome.

If a dose is missed, skip it and resume the regular schedule SAMe should be used cautiously before surgery, and pregnant or breastfeeding individuals should consult a doctor.