Introduction to defzo


Defzo is a medication primarily used to treat a condition known as Duchenne muscular dystrophy (DMD) in children aged 5 and older. DMD is a genetic disorder characterized by progressive muscle degeneration and weakness. Defzo helps manage the symptoms and improve the quality of life for those affected by this condition.


Composition of defzo


The active ingredient in Defzo is Deflazacort. This compound is a type of corticosteroid, which works by reducing inflammation and suppressing the immune system to alleviate symptoms associated with DMD.


Uses of defzo


  • Management of Duchenne muscular dystrophy (DMD) in children aged 5 and older.
  • Reduction of inflammation in the body.
  • Suppression of the immune system to prevent further muscle damage.

Side effects of defzo


Common side effects:


  • Weight gain
  • Increased appetite
  • Round face (Cushingoid appearance)
  • Upper respiratory infections (common cold)
  • Frequent urination
  • Nose and throat inflammation
  • Excessive hair growth
  • Irritability

Serious side effects:


  • Allergic reactions such as rash, itching, or swelling
  • Severe mood changes or depression
  • Vision problems
  • Severe stomach pain

Precautions of defzo


Defzo should not be taken by individuals who are allergic to Deflazacort or any of its ingredients. It should be used with caution during pregnancy and breastfeeding. Stopping Defzo suddenly can lead to steroid withdrawal syndrome, which includes symptoms like loss of appetite, nausea, vomiting, tiredness, and headache. Always consult with a healthcare provider before making any changes to your medication regimen.


How to Take defzo


  • Take Defzo once daily by mouth.
  • The recommended dose is about 0.9 mg for each kilogram of body weight.
  • It can be taken with or without food.
  • Avoid taking it with grapefruit juice as it can interfere with the medication's effectiveness.

Conclusion of defzo


Defzo is an important medication for managing Duchenne muscular dystrophy in children. By reducing inflammation and suppressing the immune system, it helps improve muscle function and quality of life. However, it is crucial to follow the prescribed dosage and take necessary precautions to avoid potential side effects. Always consult with a healthcare professional for personalized advice and guidance.


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Written By:

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Published At: Dec 10, 2024

Updated At: Jan 28, 2025

Reviewed By:

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Published At: Dec 10, 2024

Updated At: Jan 28, 2025

Disclaimer : This information is not a substitute for medical advice. Consult your healthcare provider before making any changes to your treatment . Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki.