defoset

Introduction to Defoset

Defoset is a medication primarily used to treat a condition known as Duchenne muscular dystrophy (DMD), which is a muscle weakening disease. It is specifically prescribed for children aged 5 and older. This medication helps manage the symptoms of DMD by reducing inflammation and suppressing the immune system.

Composition of Defoset

The active ingredient in Defoset is Deflazacort. When taken, it converts into an active form that binds to a part of cells called the glucocorticoid receptor. This interaction helps in reducing the production of inflammatory substances and suppressing the immune response.

Uses of Defoset

• Treatment of Duchenne muscular dystrophy (DMD) in children aged 5 and older.
• Helps in reducing inflammation.
• Suppresses the immune system to manage symptoms of DMD.

Side Effects of Defoset

Common Side Effects:

• Weight gain
• Increased appetite
• Round face (Cushingoid appearance)
• Upper respiratory infections (common cold)
• Frequent urination
• Nose and throat inflammation
• Excessive hair growth
• Irritability

Serious Side Effects:

• Allergic reactions such as rash, itching, or swelling
• Severe dizziness
• Trouble breathing

Precautions of Defoset

Defoset should not be taken by individuals who are allergic to it or any of its ingredients. It should be used with caution during pregnancy and breastfeeding. Stopping Defoset suddenly can lead to steroid withdrawal syndrome, which may cause symptoms like loss of appetite, nausea, vomiting, tiredness, and headache.

How to Take Defoset

• Take Defoset once daily by mouth.
• The recommended dose is about 0.9 mg for each kilogram of body weight.
• It can be taken with or without food.
• Avoid taking it with grapefruit juice.

Conclusion of Defoset

Defoset is an important medication for managing Duchenne muscular dystrophy in children. By reducing inflammation and suppressing the immune system, it helps alleviate the symptoms of this muscle weakening disease. However, it is crucial to follow the prescribed dosage and take necessary precautions to avoid potential side effects and complications.