defglobe

Introduction to defglobe

Defglobe is a medication primarily used to treat a condition known as Duchenne muscular dystrophy (DMD) in children aged 5 and older. DMD is a genetic disorder characterized by progressive muscle degeneration and weakness. Defglobe helps manage the symptoms and improve the quality of life for those affected by this condition.

Composition of defglobe

The active ingredient in defglobe is Deflazacort. This compound is a type of corticosteroid, which works by reducing inflammation and suppressing the immune system. It is converted into an active form in the body that interacts with the glucocorticoid receptor in cells, leading to a decrease in inflammatory substances.

Uses of defglobe

• Treatment of Duchenne muscular dystrophy (DMD) in children aged 5 and older
• Reduction of inflammation in various conditions
• Suppression of the immune system to manage autoimmune diseases

Side effects of defglobe

Common side effects:

• Weight gain
• Increased appetite
• Round face (Cushingoid appearance)
• Upper respiratory infections (common cold)
• Frequent urination
• Nose and throat inflammation
• Excessive hair growth
• Irritability

Serious side effects:

• Allergic reactions such as rash, itching, or swelling
• Severe mood changes or depression
• Vision problems
• Severe stomach pain
• Signs of infection (fever, persistent sore throat)

Precautions of defglobe

Defglobe should not be taken by individuals who are allergic to it or any of its ingredients. It should be used with caution during pregnancy and breastfeeding. Stopping defglobe suddenly can lead to steroid withdrawal syndrome, which includes symptoms like loss of appetite, nausea, vomiting, tiredness, and headache. Always consult a healthcare provider before making any changes to the dosage.

How to Take defglobe

• Take defglobe once daily by mouth.
• The recommended dose is about 0.9 mg for each kilogram of body weight.
• It can be taken with or without food.
• Avoid taking it with grapefruit juice.

Conclusion of defglobe

Defglobe is an effective medication for managing Duchenne muscular dystrophy in children, helping to reduce inflammation and suppress the immune system. While it offers significant benefits, it is important to be aware of potential side effects and take necessary precautions. Always follow the guidance of a healthcare professional when using defglobe to ensure safe and effective treatment.