code

Introduction to Deflazacort

Deflazacort is a medication primarily used to treat a condition known as Duchenne muscular dystrophy (DMD) in children aged 5 and older. This condition leads to muscle weakening and deterioration over time.

Composition of Deflazacort

Deflazacort is a corticosteroid that works by reducing inflammation and suppressing the immune system. It converts into an active form that binds to the glucocorticoid receptor in cells, leading to a decrease in inflammatory substances.

Uses of Deflazacort

• Treatment of Duchenne muscular dystrophy (DMD) in children
• Reduction of inflammation in various conditions
• Suppression of the immune response

Side Effects of Deflazacort

Common Side Effects:

• Weight gain
• Increased appetite
• Round face (Cushingoid appearance)
• Upper respiratory infections
• Frequent urination
• Nose and throat inflammation
• Excessive hair growth
• Irritability

Serious Side Effects:

• Allergic reactions
• Severe mood changes
• High blood pressure
• Osteoporosis

Precautions of Deflazacort

Deflazacort should not be used by individuals who are allergic to it or any of its ingredients. Caution is advised during pregnancy and breastfeeding. Abruptly stopping the medication can lead to steroid withdrawal syndrome, which includes symptoms like loss of appetite, nausea, vomiting, tiredness, and headache.

How to Take Deflazacort

• Take once daily by mouth
• Recommended dose is about 0.9 mg per kilogram of body weight
• Can be taken with or without food
• Avoid taking with grapefruit juice

Conclusion of Deflazacort

Deflazacort is an effective treatment for Duchenne muscular dystrophy in children, helping to manage symptoms by reducing inflammation and suppressing the immune system. It is important to follow the prescribed dosage and take necessary precautions to avoid potential side effects.