Immunotherapy: A Treatment For Lung Cancer

Have you heard about immunotherapy, a promising approach to fighting cancer? 

• This innovative treatment works with your body's immune system to fight cancer. Immune checkpoint inhibitors are a type of immunotherapy that block a protein interaction between immune and cancer cells, ultimately reducing the immune response to cancer. 

• You may be wondering how cancer cells can evade the immune system. Well, cancer cells have ways to avoid destruction by the immune system, such as genetic changes that make them less visible to the immune system, proteins on their surface that turn off immune cells, or even changing the normal cells around the tumor so they interfere with how the immune system responds to the cancer cells. 

• The goal of immunotherapy is to help the immune system to better act against cancer. Researchers have found that some patients with high levels of an immune checkpoint protein called PD-L1 may be more responsive to immune checkpoint inhibitors. Another marker for immunotherapy response is tumor mutational burden (TMB), which refers to the amount of mutations in the cancer cell DNA. 

• Tumor-infiltrating lymphocytes (TILs) are immune cells that are sometimes found in and around tumors. These cells are a sign that the immune system is responding to the tumor, and people whose tumors contain TILs often do better than people whose tumors don’t contain them. 

• Several immune checkpoint inhibitors have been approved for advanced lung cancer, including pembrolizumab, atezolizumab, cemiplimab, durvalumab, and nivolumab. However, deciding which patients are most likely to benefit from immunotherapies remains a challenge. 

Source:- https://www.cancer.gov/about-cancer/treatment/types/immunotherapy https://www.cancer.gov/types/lung/research#:~:text=Lung Cancer Research Results,-The following are&text=Enhertu Marks First Targeted Therapy,in People with Lung Cancer 

Disclaimer:- This information is intended to supplement, not substitute, advice from your healthcare provider or doctor. It does not cover all possible uses, precautions, interactions, or side effects, and may not be appropriate for your specific healthcare needs. Always consult with your doctor or another qualified healthcare provider before modifying or discontinuing any prescribed portion of your healthcare plan or treatment, in order to determine the best course of therapy for you. Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki.

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