Zileuton
Asthma
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Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
5-Lipoxygenase Inhibitor
Controlled Drug Substance
No
zileuton
Summary
Zileuton is used to manage asthma, which is a condition that causes difficulty in breathing due to inflamed airways. It helps reduce symptoms like wheezing and shortness of breath.
Zileuton works by blocking the production of leukotrienes, which are chemicals that cause inflammation and constriction in the airways. This helps improve breathing in people with asthma.
The usual starting dose for adults is 600 mg taken four times a day. It should be taken with food to help absorption. Always follow your doctor's instructions for your specific health needs.
Common side effects include headache, nausea, and dizziness. These are usually mild, but if they persist or worsen, you should contact your doctor.
Zileuton can cause liver problems, so regular liver function tests are necessary. Avoid alcohol, and do not take it if you have active liver disease or are allergic to its ingredients.
Indications and Purpose
How does Zileuton work?
Zileuton works by inhibiting the enzyme 5-lipoxygenase, which reduces the production of leukotrienes. Leukotrienes are chemicals in the body that cause inflammation and constriction of airways. By blocking their production, Zileuton helps improve breathing in people with asthma.
Is Zileuton effective?
Zileuton is effective in managing asthma by reducing inflammation in the airways. Clinical studies show it helps improve lung function and reduce asthma symptoms. It works by blocking the production of leukotrienes, which are chemicals in the body that cause inflammation.
What is Zileuton?
Zileuton is a medication used to manage asthma. It belongs to a class of drugs called leukotriene synthesis inhibitors, which work by reducing inflammation in the airways. This helps improve breathing and reduce asthma symptoms.
Directions for Use
For how long do I take Zileuton?
Zileuton is usually a long-term medication for managing asthma. You'll typically take it every day as a lifelong treatment unless your doctor suggests otherwise. How long you'll need this medication depends on your body's response and changes in your overall health.
How do I dispose of Zileuton?
If you can, bring unused Zileuton to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of it properly. If you can't find a take-back program, you can throw it in the trash at home. Mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away.
How do I take Zileuton?
Take Zileuton as prescribed by your doctor, usually twice daily. It's best to take it with food to help your body absorb the medication better. Do not crush or chew the tablets. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Avoid taking two doses at once.
How long does it take for Zileuton to start working?
Zileuton begins working in your body shortly after you take it, but it may take several weeks to notice significant improvements in asthma symptoms. How quickly it works can depend on your overall health and how well you follow your treatment plan.
How should I store Zileuton?
Store Zileuton at room temperature, away from moisture and light. Keep it in a tightly closed container. Don't store it in humid places like bathrooms. Always keep it out of children's reach to prevent accidental swallowing.
What is the usual dose of Zileuton?
The usual starting dose of Zileuton for adults is 600 mg taken four times a day. Your doctor may adjust your dose based on your response to the medication. Always follow your doctor's specific dosing instructions for your personal health needs.
Warnings and Precautions
Can I take Zileuton with other prescription drugs?
Zileuton can interact with certain medications, increasing the risk of liver damage. It's important to inform your doctor about all the medications you're taking, including over-the-counter drugs and supplements, to avoid potential interactions.
Can Zileuton be taken safely while breastfeeding?
Zileuton is not recommended while breastfeeding. We don't have much information about whether this medication passes into human breast milk. If you're taking Zileuton and want to breastfeed, talk with your doctor about safer medication options.
Can Zileuton be taken safely while pregnant?
Zileuton is not recommended during pregnancy unless absolutely necessary. Limited data is available on its safety in pregnant women. If you're pregnant or planning to become pregnant, talk with your doctor about the safest way to manage your asthma.
Does Zileuton have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Zileuton include headache, nausea, and dizziness. Serious side effects can include liver problems. If you notice any new or worsening symptoms, contact your doctor immediately.
Does Zileuton have any safety warnings?
Zileuton has important safety warnings. It can cause liver problems, so regular liver function tests are necessary. If you experience symptoms like nausea, fatigue, or yellowing of the skin, contact your doctor immediately. Not adhering to these warnings can lead to serious liver damage.
Is it safe to drink alcohol while taking Zileuton?
It's best to avoid alcohol while taking Zileuton. Alcohol can increase the risk of liver damage, which is a serious side effect of Zileuton. If you do choose to drink, limit your alcohol intake and talk with your doctor about your specific health situation.
Is it safe to exercise while taking Zileuton?
You can exercise while taking Zileuton. This medication helps manage asthma, which can improve your ability to exercise. However, if you experience symptoms like dizziness or shortness of breath during exercise, slow down or stop and rest. Talk with your doctor if you have concerns.
Is it safe to stop Zileuton?
Zileuton is usually used for long-term management of asthma. Stopping it suddenly can worsen your asthma symptoms. Always talk with your doctor before stopping Zileuton. They might suggest gradually reducing your dose or switching to a different medication to keep your condition under control.
Is Zileuton addictive?
Zileuton is not addictive or habit-forming. This medication doesn't cause dependency or withdrawal symptoms when you stop taking it. If you have concerns about medication dependence, you can feel confident that Zileuton doesn't carry this risk while managing your health condition.
Is Zileuton safe for the elderly?
Elderly individuals may be more vulnerable to the side effects of Zileuton, such as liver problems. Regular monitoring of liver function is important. Always consult your doctor about the risks and benefits of using Zileuton if you are elderly.
What are the most common side effects of Zileuton?
Side effects are unwanted reactions that can happen when taking a medication. Common side effects of Zileuton include headache, nausea, and dizziness. If you notice new symptoms after starting Zileuton, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking Zileuton?
Don't take Zileuton if you have active liver disease or a history of liver problems. It's also contraindicated in people allergic to its ingredients. Always consult your doctor about these concerns before starting Zileuton.
