Zafirlukast

Asthma

Drug Status

approvals.svg

Government Approvals

US(FDA)

approvals.svg

WHO Essential Medicine

NO

approvals.svg

Known Teratogen

No

approvals.svg

Pharmaceutical Class

Leukotriene Receptor Antagonist

approvals.svg

Controlled Drug Substance

No

Video Thumbnail
Drug Ingredient

Zafirlukast

Summary

  • Zafirlukast is used to manage asthma, which is a condition that affects your airways and causes breathing difficulties. It helps reduce asthma symptoms and improve breathing by being part of a comprehensive asthma management plan.

  • Zafirlukast works by blocking leukotrienes, which are substances in the body that cause inflammation in the airways. This action helps reduce swelling and narrowing of the airways, improving breathing and reducing asthma symptoms.

  • The usual starting dose of Zafirlukast for adults is 20 mg taken twice daily. It should be taken on an empty stomach, either one hour before or two hours after meals. Always follow your doctor's specific dosing instructions.

  • Common side effects of Zafirlukast include headache and nausea, which are unwanted reactions to the medication. These effects vary from person to person and are usually mild. If you notice new symptoms, talk with your doctor.

  • Zafirlukast may cause liver problems, so watch for symptoms like nausea, fatigue, or jaundice, which is yellowing of the skin or eyes. Do not take Zafirlukast if you're allergic to it or have severe liver problems. Always consult your doctor about these concerns.

Indications and Purpose

How does Zafirlukast work?

Zafirlukast works by blocking leukotrienes, which are substances in the body that cause inflammation in the airways. Think of it like putting a barrier in place to stop these substances from causing swelling and narrowing of the airways. This helps reduce asthma symptoms and improve breathing. Zafirlukast is effective in managing asthma when taken regularly as part of a comprehensive treatment plan.

Is Zafirlukast effective?

Zafirlukast is effective in managing asthma symptoms. It works by blocking substances in the body that cause inflammation in the airways. Clinical studies show Zafirlukast helps reduce asthma attacks and improves breathing in people with asthma. It's important to take it regularly as prescribed for the best results.

What is Zafirlukast?

Zafirlukast is a medication used to manage asthma, which is a condition that affects your airways. It belongs to a class of drugs called leukotriene receptor antagonists, which work by blocking substances in the body that cause inflammation in the airways. This helps reduce asthma symptoms and improve breathing. Zafirlukast is usually used as part of a comprehensive asthma management plan.

Directions for Use

For how long do I take Zafirlukast?

Zafirlukast is usually a long-term medication for managing asthma, which is a chronic condition. You'll typically take Zafirlukast every day as part of your asthma management plan. How long you'll need this medication depends on your body's response and any side effects you experience. Always talk with your doctor before changing or stopping your Zafirlukast treatment.

How do I dispose of Zafirlukast?

If you can, bring unused Zafirlukast to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of this medicine properly so it doesn't harm people or the environment. If you can't find a take-back program, you can throw most medicines in the trash at home. But first, take them out of their original containers, mix them with something undesirable like used coffee grounds, seal the mixture in a plastic bag, and throw it away.

How do I take Zafirlukast?

Take Zafirlukast as prescribed by your doctor, usually twice daily. It's best to take it on an empty stomach, either one hour before or two hours after meals. Do not crush or chew the tablets. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Avoid taking two doses at once.

How long does it take for Zafirlukast to start working?

Zafirlukast starts working within a few hours of taking it, but it may take several days to notice significant improvements in asthma symptoms. The full therapeutic effect can take up to a week or more. Individual factors, such as your overall health and how well you follow your asthma management plan, can affect how quickly you notice improvements. Take Zafirlukast exactly as prescribed for the best results.

How should I store Zafirlukast?

Store Zafirlukast at room temperature, away from moisture and light. Keep it in a tightly closed container. Don't store it in humid places like bathrooms, as moisture can affect the medication's effectiveness. Always keep Zafirlukast out of children's reach to prevent accidental swallowing. Check the expiration date regularly and dispose of any unused or expired medication properly.

What is the usual dose of Zafirlukast?

The usual starting dose of Zafirlukast for adults is 20 mg taken twice daily. It's important to follow your doctor's specific dosing instructions. Dose adjustments may be necessary for special populations, such as children or the elderly. Always consult your doctor for personalized dosing recommendations based on your health needs.

Warnings and Precautions

Can I take Zafirlukast with other prescription drugs?

Zafirlukast can interact with certain medications, such as warfarin, which is a blood thinner. This interaction may increase the risk of bleeding. Always inform your doctor about all the medications you take to prevent potential interactions. Your doctor can help adjust your treatment plan to ensure it's safe and effective.

Can Zafirlukast be taken safely while breastfeeding?

Zafirlukast's safety during breastfeeding isn't well-established. It's unclear if the medication passes into breast milk. If you're breastfeeding or planning to breastfeed, talk with your doctor about the safest way to manage your asthma. They can help determine if Zafirlukast is appropriate for you or suggest alternative treatments.

Can Zafirlukast be taken safely while pregnant?

The safety of Zafirlukast during pregnancy isn't well-established. Limited data is available, so it's important to weigh the benefits and risks with your doctor. If you're pregnant or planning to become pregnant, discuss the safest way to manage your asthma with your doctor. They can help create a treatment plan that protects both you and your baby.

Does Zafirlukast have adverse effects?

Adverse effects are unwanted reactions to a medication. Common adverse effects of Zafirlukast include headache and nausea. Serious side effects, like liver problems, are rare but require immediate medical attention. If you notice any new or worsening symptoms while taking Zafirlukast, contact your doctor. They can help determine if these symptoms are related to the medication.

Does Zafirlukast have any safety warnings?

Zafirlukast has important safety warnings. It may cause liver problems, so watch for symptoms like nausea, fatigue, or jaundice, which is yellowing of the skin or eyes. If you experience these, contact your doctor immediately. Not adhering to safety warnings can lead to serious health issues. Always follow your doctor's advice and report any new symptoms.

Is it safe to drink alcohol while taking Zafirlukast?

It's best to avoid alcohol while taking Zafirlukast. Alcohol can increase the risk of liver problems, which is a potential side effect of Zafirlukast. If you do choose to drink occasionally, limit how much alcohol you consume and watch for warning signs like nausea or fatigue. Talk with your doctor about alcohol use while taking Zafirlukast.

Is it safe to exercise while taking Zafirlukast?

You can exercise while taking Zafirlukast. This medication helps manage asthma symptoms, which can improve your ability to exercise. However, if you experience any unusual symptoms during physical activity, such as shortness of breath or chest tightness, slow down or stop exercising and rest. Talk with your doctor if you have concerns about exercising while taking Zafirlukast.

Is it safe to stop Zafirlukast?

Zafirlukast is usually used for long-term management of asthma, which is a chronic condition. Stopping it suddenly may worsen your asthma symptoms. Always talk with your doctor before stopping Zafirlukast. They might suggest gradually reducing your dose or switching to a different medication to keep your condition under control.

Is Zafirlukast addictive?

Zafirlukast is not addictive or habit-forming. This medication doesn't cause dependency or withdrawal symptoms when you stop taking it. It works by affecting your immune system to help manage asthma symptoms. You won't experience cravings for this medication or feel compelled to take more than prescribed. If you have concerns about medication dependence, Zafirlukast doesn't carry this risk.

Is Zafirlukast safe for the elderly?

Elderly patients may experience higher plasma concentrations of Zafirlukast, leading to increased side effects. They should be monitored closely, especially for liver function and infections. The dosage may need adjustment based on individual tolerance and response.

What are the most common side effects of Zafirlukast?

Side effects are unwanted reactions that can happen when taking a medication. Common side effects of Zafirlukast include headache and nausea. These effects vary from person to person. If you notice new symptoms after starting Zafirlukast, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.

Who should avoid taking Zafirlukast?

Don't take Zafirlukast if you're allergic to it or its ingredients. Serious allergic reactions, which cause rash, hives, or swelling that makes breathing difficult, require immediate medical help. Zafirlukast shouldn't be used by people with severe liver problems, as it may worsen liver function. Always consult your doctor about these concerns.