Vibegron
Overactive Urinary Bladder
Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Beta3-Adrenergic Agonist
Controlled Drug Substance
No

Vibegron
Summary
Vibegron is used to treat overactive bladder symptoms, which include frequent urination, urgency, and urge incontinence, which is the involuntary leakage of urine.
Vibegron works by activating beta-3 adrenergic receptors, which are proteins in the bladder that help relax the bladder muscles, reducing the urge to urinate and improving bladder control.
The usual starting dose of Vibegron for adults is 75 mg taken once daily. It can be taken with or without food, and the tablet should be swallowed whole, not crushed or chewed.
Common side effects of Vibegron include headache, diarrhea, and nausea, which are usually mild and may go away on their own.
Vibegron may cause increased blood pressure and urinary retention, which is difficulty emptying the bladder. It should not be taken by those allergic to it or its ingredients.
Indications and Purpose
How does Vibegron work?
Vibegron works by activating beta-3 adrenergic receptors in the bladder, which helps relax the bladder muscles. This relaxation reduces the urge to urinate and improves bladder control. Think of it like easing the tension in a balloon, allowing it to hold more air without bursting. This mechanism helps manage overactive bladder symptoms effectively.
Is Vibegron effective?
Vibegron is effective in treating overactive bladder symptoms, such as frequent urination and urgency. Clinical studies show that Vibegron significantly reduces these symptoms, improving quality of life for many patients. It works by relaxing the bladder muscles, allowing for better control over urination. If you have questions about Vibegron's effectiveness for your condition, talk with your doctor.
What is Vibegron?
Vibegron is a medication used to treat overactive bladder symptoms, such as frequent urination and urgency. It belongs to a class of drugs called beta-3 adrenergic agonists, which work by relaxing the bladder muscles. This helps reduce the urge to urinate and improves bladder control. Vibegron is typically used when other treatments haven't been effective.
Directions for Use
For how long do I take Vibegron?
Vibegron is usually taken long-term for managing overactive bladder symptoms. You'll typically take it every day as part of your ongoing treatment plan. How long you'll need this medication depends on your body's response and any side effects you experience. Always talk with your doctor before changing or stopping your Vibegron treatment.
How do I dispose of Vibegron?
To dispose of Vibegron, take it to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of it properly to prevent harm to people or the environment. If you can't find a take-back program, you can throw it in the trash at home. Mix it with something undesirable, like used coffee grounds, seal it in a plastic bag, and throw it away.
How do I take Vibegron?
Take Vibegron as prescribed by your doctor, usually once daily. You can take it with or without food. Swallow the tablet whole; do not crush or chew it. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not take two doses at once. Always follow your doctor's specific instructions.
How long does it take for Vibegron to start working?
Vibegron may start working within a few days, but it can take several weeks to achieve its full effect. Individual factors like your overall health and how your body responds to the medication can affect how quickly you notice improvements. Take Vibegron exactly as prescribed for the best results. If you have questions about how Vibegron is working, talk with your doctor.
How should I store Vibegron?
Store Vibegron at room temperature, away from moisture and light. Keep it in its original container with the lid tightly closed. Avoid storing it in humid places like bathrooms. Always keep Vibegron out of reach of children to prevent accidental ingestion. Check the expiration date regularly and properly dispose of any unused or expired medication.
What is the usual dose of Vibegron?
The usual starting dose of Vibegron for adults is 75 mg once daily. Your doctor will provide specific dosing instructions based on your health needs. Always follow your doctor's guidance on how to take Vibegron. If you have any questions about your dose or how to take this medication, consult your healthcare provider.
Warnings and Precautions
Can I take Vibegron with other prescription drugs?
Vibegron may interact with certain medications, such as digoxin, which is used to treat heart conditions. This interaction can increase digoxin levels in your blood. Always inform your doctor about all the medications you take to prevent potential interactions. Your doctor can help manage any interactions and adjust your treatment plan as needed.
Can Vibegron be taken safely while breastfeeding?
The safety of Vibegron while breastfeeding is not well-established. It's unclear if Vibegron passes into breast milk or affects milk production. If you're breastfeeding or planning to breastfeed, talk with your doctor about the safest options for managing your condition. Your doctor can help determine the best treatment plan for you and your baby.
Can Vibegron be taken safely while pregnant?
The safety of Vibegron during pregnancy is not well-established. Limited data is available, so it's important to discuss with your doctor if you're pregnant or planning to become pregnant. Your doctor can help determine the safest treatment options for managing your condition during pregnancy. Always follow your doctor's advice regarding medication use while pregnant.
Does Vibegron have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Vibegron include headache, diarrhea, and nausea. These effects are usually mild. Serious side effects are rare but can include increased blood pressure and urinary retention, which is difficulty emptying the bladder. If you experience any new or worsening symptoms, contact your doctor. They can help determine if these symptoms are related to Vibegron and provide appropriate care.
Does Vibegron have any safety warnings?
Vibegron has safety warnings you should be aware of. It may cause increased blood pressure, so regular monitoring is important. If you experience symptoms like severe headache, chest pain, or vision changes, seek medical help. Vibegron can also cause urinary retention, which is difficulty emptying the bladder. If you notice any unusual symptoms, contact your doctor promptly. Always follow your doctor's advice and report any side effects.
Is it safe to drink alcohol while taking Vibegron?
It's best to avoid alcohol while taking Vibegron. Alcohol can increase the risk of side effects like dizziness or drowsiness. If you choose to drink, limit your alcohol intake and be cautious of any symptoms like dizziness or lightheadedness. Talk with your doctor about alcohol use while taking Vibegron to get personalized advice based on your health situation.
Is it safe to exercise while taking Vibegron?
You can exercise while taking Vibegron, but be mindful of how your body feels. Vibegron may cause dizziness or drowsiness in some people. If you experience these symptoms, avoid strenuous activities until you feel better. Drink plenty of water before, during, and after exercise to stay hydrated. If you have concerns about exercising while taking Vibegron, talk with your doctor.
Is it safe to stop Vibegron?
It's important to talk with your doctor before stopping Vibegron. Stopping suddenly may cause your symptoms to return or worsen. Your doctor can guide you on how to safely stop the medication if needed. They might suggest gradually reducing your dose or switching to a different treatment to manage your condition effectively.
Is Vibegron addictive?
Vibegron is not addictive or habit-forming. This medication doesn't cause dependency or withdrawal symptoms when you stop taking it. Vibegron works by relaxing the bladder muscles to help reduce urinary symptoms. It doesn't affect brain chemistry in ways that could lead to addiction. If you have concerns about medication dependence, you can feel confident that Vibegron doesn't carry this risk.
Is Vibegron safe for the elderly?
Elderly individuals may be more sensitive to the effects of Vibegron, especially regarding blood pressure changes. It's important for older adults to have regular check-ups with their doctor to monitor their response to the medication. Vibegron is generally safe for the elderly, but careful monitoring is advised to prevent any potential side effects or complications.
What are the most common side effects of Vibegron?
Side effects are unwanted reactions that can happen when taking a medication. Common side effects of Vibegron include headache, diarrhea, and nausea. These effects are usually mild and may go away on their own. If you notice new symptoms after starting Vibegron, they might be temporary or unrelated to the medication. Talk with your doctor if you have concerns about side effects.
Who should avoid taking Vibegron?
Don't take Vibegron if you're allergic to it or its ingredients. Serious allergic reactions, which cause rash, hives, or swelling that makes breathing difficult, require immediate medical help. Vibegron should be used with caution in people with severe liver or kidney problems. Always consult your doctor about any health conditions you have before starting Vibegron.