Vericiguat
.svg)
Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
Soluble Guanylate Cyclase Stimulator
Controlled Drug Substance
No
vericiguat
Summary
Vericiguat is used to treat heart failure, which is when the heart can't pump blood effectively. It helps improve symptoms like shortness of breath and fatigue, and reduces the risk of hospitalization and death from heart problems.
Vericiguat works by stimulating an enzyme called soluble guanylate cyclase, which helps relax blood vessels and improve blood flow. This reduces the workload on the heart and improves symptoms of heart failure.
The usual starting dose of Vericiguat for adults is 2.5 mg once daily with food. Your doctor may gradually increase your dose to a maximum of 10 mg daily based on your response and tolerance.
Common side effects of Vericiguat include low blood pressure and dizziness. These effects vary from person to person and may require medical attention if they become severe or persistent.
Vericiguat is not recommended during pregnancy due to potential harm to the unborn baby. It can interact with medications that increase cGMP levels, leading to dangerously low blood pressure. Always consult your doctor about these concerns.
Indications and Purpose
How does Vericiguat work?
Vericiguat works by stimulating an enzyme called soluble guanylate cyclase, which helps relax blood vessels and improve blood flow. This reduces the workload on the heart and improves symptoms of heart failure. Think of it like opening a valve to allow more water to flow through a pipe, easing the pressure and improving function.
Is Vericiguat effective?
Vericiguat is effective in treating heart failure, which is when your heart can't pump blood effectively. Clinical studies show Vericiguat reduces the risk of hospitalization and death from heart problems in patients with chronic heart failure. This medication helps improve heart health and quality of life for those affected.
What is Vericiguat?
Vericiguat is a medication used to treat heart failure, which is when your heart can't pump blood effectively. It belongs to a class of drugs called soluble guanylate cyclase stimulators. Vericiguat works by helping blood vessels relax and improve blood flow, reducing the workload on the heart and improving symptoms of heart failure.
Directions for Use
For how long do I take Vericiguat?
Vericiguat is usually a long-term medication for managing chronic heart failure. You'll typically take it every day as a lifelong treatment unless your doctor suggests otherwise. Stopping this medication without medical advice could cause your condition to worsen. Always talk with your doctor before changing or stopping your Vericiguat treatment.
How do I dispose of Vericiguat?
Bring unused Vericiguat to a drug take-back program or collection site at a pharmacy or hospital. If you can't find a take-back program, you can throw it in the trash at home. First, mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away.
How do I take Vericiguat?
Take Vericiguat once daily with food. Swallow the tablet whole; do not crush or chew it. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not take two doses at once. Follow your doctor's specific instructions for taking Vericiguat.
How long does it take for Vericiguat to start working?
Vericiguat begins working in your body shortly after you take it, but you may not notice all the benefits right away. It may take several weeks to see significant improvements in heart failure symptoms. How quickly the medication works can depend on your overall health and response to treatment. Take it exactly as prescribed for the best results.
How should I store Vericiguat?
Store Vericiguat tablets at room temperature, away from moisture and light. Keep the medication in a tightly closed container. Don't store it in humid places like bathrooms. Always store Vericiguat out of children's reach to prevent accidental swallowing. Check the expiration date regularly and properly dispose of any unused or expired medication.
What is the usual dose of Vericiguat?
The usual starting dose of Vericiguat for adults is 2.5 mg once daily with food. Your doctor may gradually increase your dose to a maximum of 10 mg daily based on your response and tolerance. Always follow your doctor's specific dosing instructions for your personal health needs.
Warnings and Precautions
Can I take Vericiguat with other prescription drugs?
Vericiguat can interact with medications that increase cGMP levels, such as nitrates and PDE5 inhibitors, leading to dangerously low blood pressure. Always inform your doctor about all the medications you take to avoid potential interactions. Your doctor can help manage your medications safely.
Can Vericiguat be taken safely while breastfeeding?
Vericiguat is not recommended while breastfeeding. There is limited information on whether it passes into human breast milk. If you're taking Vericiguat and want to breastfeed, talk with your doctor about safer medication options that would allow you to nurse your baby safely.
Can Vericiguat be taken safely while pregnant?
Vericiguat is not recommended during pregnancy due to potential harm to the unborn baby. There is limited information on its safety in pregnant women. If you're pregnant or planning to become pregnant, talk with your doctor about the safest treatment options for your condition.
Does Vericiguat have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Vericiguat include low blood pressure and dizziness. Serious side effects are rare but can include fainting or severe allergic reactions. If you experience any new or worsening symptoms, contact your doctor immediately for advice.
Does Vericiguat have any safety warnings?
Yes, Vericiguat has safety warnings. It can cause low blood pressure, especially in people who are dehydrated or taking other blood pressure medications. This may lead to dizziness or fainting. It's important to stay hydrated and avoid sudden changes in posture. If you experience symptoms like dizziness or fainting, contact your doctor immediately.
Is it safe to drink alcohol while taking Vericiguat?
It's best to avoid alcohol while taking Vericiguat. Alcohol can increase the risk of low blood pressure, which may lead to dizziness or fainting. If you choose to drink occasionally, limit your alcohol intake and watch for warning signs like dizziness or fainting. Talk with your doctor about alcohol use while taking Vericiguat.
Is it safe to exercise while taking Vericiguat?
You can exercise while taking Vericiguat, but be cautious. This medication can cause low blood pressure, leading to dizziness during exercise. Stay hydrated and avoid strenuous activities if you feel dizzy. If you notice symptoms like dizziness or unusual fatigue, slow down or stop exercising and rest.
Is it safe to stop Vericiguat?
Vericiguat is usually used long-term for chronic heart failure. Stopping it suddenly can worsen your condition. Always talk with your doctor before stopping Vericiguat. They might suggest gradually reducing your dose or switching to a different medication to keep your condition under control.
Is Vericiguat addictive?
Vericiguat is not addictive or habit-forming. This medication doesn't cause dependency or withdrawal symptoms when you stop taking it. You won't experience cravings for this medication or feel compelled to take more than prescribed. If you have concerns about medication dependence, you can feel confident that Vericiguat doesn't carry this risk.
Is Vericiguat safe for the elderly?
Elderly individuals are more vulnerable to the safety risks of medications like Vericiguat. They may experience more pronounced side effects such as low blood pressure and dizziness. It's important for elderly patients to be closely monitored by their healthcare provider while taking Vericiguat to ensure safety and effectiveness.
What are the most common side effects of Vericiguat?
Side effects are unwanted reactions that can happen when taking a medication. Common side effects of Vericiguat include dizziness and low blood pressure. These effects vary from person to person. If you notice new symptoms after starting Vericiguat, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking Vericiguat?
Do not take Vericiguat if you're allergic to it or its ingredients. It's contraindicated in pregnancy due to potential harm to the unborn baby. Avoid using it with other medications that increase cGMP levels, as this can lead to dangerously low blood pressure. Always consult your doctor about these concerns.
Forms / Brands
