Venlafaxine

Depressive Disorder, Pain ... show more

Drug Status

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Government Approvals

US(FDA), UK(BNF)

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WHO Essential Medicine

NO

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Known Teratogen

NO

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Pharmaceutical Class

Serotonin and Norepinephrine Reuptake Inhibitor

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Controlled Drug Substance

NO

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Drug Ingredient

Venlafaxine

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Summary

  • Venlafaxine is primarily used to treat major depressive disorder, generalized anxiety disorder, social anxiety disorder, and panic disorder. It is also used off-label for posttraumatic stress disorder.

  • Venlafaxine works by increasing the levels of serotonin and norepinephrine, two neurotransmitters in the brain. This helps to improve mood, reduce anxiety, and alleviate depressive symptoms.

  • Venlafaxine is typically started at 75 mg per day for depression, and for anxiety disorders, it may increase to 225 mg. It's taken orally, usually once daily, with food.

  • Common side effects include nausea, dry mouth, dizziness, insomnia, and sweating. More serious effects can include increased blood pressure, sexual dysfunction, weight changes, and serotonin syndrome.

  • Venlafaxine should be used with caution in individuals with high blood pressure, seizures, heart disease, or suicidal thoughts. It should not be used by people with hypersensitivity to the drug or monoamine oxidase inhibitors. Abrupt discontinuation can cause withdrawal symptoms.

Indications and Purpose

Directions for Use

Warnings and Precautions