Valsartan
Hypertension, Left Ventricular Dysfunction ... show more
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
Definite
Pharmaceutical Class
Angiotensin 2 Receptor Blocker
Controlled Drug Substance
NO
Valsartan
Learn more about this medicine -
Click HereSummary
Valsartan is used to treat high blood pressure, heart failure, and to increase survival rates after a heart attack. It can be used in adults and children over 6 years old.
Valsartan is an angiotensin II receptor blocker (ARB). It works by relaxing and widening blood vessels, which lowers blood pressure and improves blood flow. This reduces the strain on the heart and helps prevent complications like heart attacks and strokes.
For adults, the usual starting dose for hypertension is 80 mg or 160 mg once daily, with a maximum dose of 320 mg per day. For heart failure, the starting dose is 40 mg twice daily. For children aged 6 to 16 years, the starting dose is typically 1 mg/kg once daily.
Common side effects of Valsartan include headache, dizziness, fatigue, and diarrhea. Serious but rare side effects include swelling of the face, lips or throat, kidney impairment, and high potassium levels.
Valsartan can cause fetal harm if taken during pregnancy. It's also not recommended for patients with severe liver impairment or those with hypersensitivity to Valsartan. Regular monitoring of blood pressure, kidney function, and potassium levels is recommended.
Indications and Purpose
How does one know if Valsartan is working?
The benefit of Valsartan is evaluated by monitoring blood pressure levels to ensure they are within the target range. Regular follow-up appointments with a healthcare provider are important to assess the effectiveness of the medication and make any necessary dosage adjustments. Blood tests may also be conducted to monitor kidney function and potassium levels.
How does Valsartan work?
Valsartan works by blocking the action of angiotensin II, a natural substance in the body that causes blood vessels to tighten. By preventing this action, Valsartan helps to relax and widen blood vessels, which lowers blood pressure and improves blood flow, making it easier for the heart to pump blood.
Is Valsartan effective?
Valsartan is an angiotensin II receptor antagonist that effectively lowers blood pressure by blocking the action of substances that tighten blood vessels. Clinical trials have shown that it reduces the risk of cardiovascular events like strokes and heart attacks in patients with hypertension. It also improves survival rates in heart failure patients and those who have had a heart attack.
What is Valsartan?
Valsartan is used to treat high blood pressure and heart failure, and to improve survival after a heart attack. It belongs to a class of medications called angiotensin II receptor antagonists, which work by blocking the action of substances that tighten blood vessels, allowing blood to flow more smoothly and the heart to pump more efficiently.
What is Valsartan used for?
Valsartan is indicated for the treatment of high blood pressure (hypertension) in adults and children over 6 years old. It is also used to treat heart failure and to improve survival after a heart attack by reducing the risk of cardiovascular mortality. It may be used alone or in combination with other medications.
Directions for Use
For how long do I take Valsartan?
Valsartan is typically used as a long-term treatment for conditions like high blood pressure and heart failure. The duration of use depends on the individual's condition and response to the medication. It is important to continue taking Valsartan as prescribed by your doctor, even if you feel well, and not to stop without consulting your healthcare provider.
How do I take Valsartan?
Valsartan can be taken with or without food. It is important to take it at the same time each day to maintain consistent blood levels. Avoid using salt substitutes containing potassium unless advised by your doctor. Follow your healthcare provider's instructions regarding any dietary restrictions.
How long does it take for Valsartan to start working?
Valsartan begins to lower blood pressure within 2 weeks, with the full effect usually seen after 4 weeks of treatment. It is important to continue taking the medication as prescribed, even if you do not feel any immediate effects, as it may take time to notice improvements in your condition.
How should I store Valsartan?
Store Valsartan tablets at room temperature, between 68°F to 77°F (20°C to 25°C), away from excess heat and moisture. Keep the medication in its original container, tightly closed, and out of reach of children. The suspension form can be stored at room temperature for up to 30 days or refrigerated for up to 75 days.
What is the usual dose of Valsartan?
For adults, the usual starting dose of Valsartan for hypertension is 80 mg or 160 mg once daily, which can be adjusted up to 320 mg daily if needed. For heart failure, the starting dose is 40 mg twice daily, which can be increased to 160 mg twice daily. For children aged 6 to 16 years, the starting dose is 1 mg/kg once daily, up to a maximum of 160 mg daily. Always follow your doctor's specific dosage instructions.
Warnings and Precautions
Can I take Valsartan with other prescription drugs?
Valsartan can interact with other medications that affect the renin-angiotensin system, such as ACE inhibitors and aliskiren, increasing the risk of hypotension, hyperkalemia, and renal impairment. It may also interact with NSAIDs, which can reduce its antihypertensive effect and worsen kidney function. Monitoring is advised when used with potassium supplements or diuretics.
Can I take Valsartan with vitamins or supplements?
Valsartan can interact with potassium supplements and salt substitutes containing potassium, leading to increased potassium levels in the blood. This can cause hyperkalemia, which is potentially dangerous. It is important to inform your healthcare provider about all supplements you are taking to avoid adverse interactions and ensure safe use of Valsartan.
Can Valsartan be taken safely while breastfeeding?
Valsartan is not recommended for use while breastfeeding due to the potential for serious adverse effects in the nursing infant. It is important to discuss with your healthcare provider the risks and benefits of continuing the medication while breastfeeding and to consider alternative treatments if necessary.
Can Valsartan be taken safely while pregnant?
Valsartan is not recommended during pregnancy, especially in the second and third trimesters, as it can cause fetal harm, including kidney damage and death. If pregnancy is detected, Valsartan should be discontinued immediately. Alternative treatments with a safer profile during pregnancy should be considered. Consult your healthcare provider for guidance.
Is it safe to drink alcohol while taking Valsartan?
Drinking alcohol while taking Valsartan can increase the risk of side effects such as dizziness and lightheadedness, especially when standing up. It is advisable to limit alcohol consumption and discuss with your doctor how much alcohol is safe for you to consume while on this medication.
Is it safe to exercise while taking Valsartan?
Valsartan does not typically limit the ability to exercise. However, it can cause dizziness or lightheadedness, especially when starting the medication or increasing the dose. If you experience these symptoms, it is advisable to avoid strenuous activities until you know how the medication affects you. Consult your doctor if you have concerns about exercising while taking Valsartan.
Is Valsartan safe for the elderly?
Elderly patients may be more sensitive to the effects of Valsartan, particularly the risk of dizziness and hypotension. It is important to monitor blood pressure regularly and adjust the dose as needed. Elderly patients should also be cautious when standing up quickly to avoid falls. Consult a healthcare provider for personalized advice and monitoring.
Who should avoid taking Valsartan?
Valsartan should not be used during pregnancy as it can harm the fetus. It is contraindicated in patients with known hypersensitivity to the drug and those with diabetes taking aliskiren. Caution is advised in patients with renal or hepatic impairment. It may cause dizziness, hypotension, and hyperkalemia, so regular monitoring is recommended.
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