Trimethobenzamide
Nausea, Vomiting
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Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
Antiemetic
Controlled Drug Substance
No
Trimethobenzamide
Summary
Trimethobenzamide is used to treat nausea and vomiting that can occur after surgery and due to gastroenteritis, commonly known as the stomach flu.
Trimethobenzamide works by decreasing activity in a specific area of the brain called the chemoreceptor trigger zone, which is responsible for causing nausea and vomiting.
The usual adult dosage for Trimethobenzamide is 300 mg taken orally three or four times a day. It's important to follow the instructions provided by your healthcare provider.
Common side effects of Trimethobenzamide include drowsiness, dizziness, headache, and diarrhea. Serious side effects can include seizures, confusion, and jaundice. If you experience any of these, contact your healthcare provider immediately.
Trimethobenzamide can cause serious CNS reactions, hepatotoxicity, and extrapyramidal symptoms. It is not recommended for those with hypersensitivity to the drug or for those with liver impairment. It's also advised to avoid alcohol while taking this medication.
Indications and Purpose
How does Trimethobenzamide work?
Trimethobenzamide works by affecting the brain's vomiting center to help control nausea and vomiting. It blocks signals in the brain that trigger these symptoms. Think of it like turning down the volume on a loudspeaker. By reducing the intensity of the signals, Trimethobenzamide helps calm the stomach and prevent vomiting. This makes it effective for treating nausea and vomiting caused by various conditions, such as surgery or illness.
Is Trimethobenzamide effective?
Trimethobenzamide is effective for treating nausea and vomiting. It works by affecting the brain's vomiting center to help control these symptoms. Clinical studies and patient experiences support its effectiveness in providing relief from nausea and vomiting. If you have concerns about how well Trimethobenzamide is working for you, talk with your doctor. They can assess your symptoms and adjust your treatment plan if needed.
What is Trimethobenzamide?
Trimethobenzamide is a medication used to treat nausea and vomiting. It belongs to a class of drugs called antiemetics, which help control nausea and vomiting by affecting the brain's vomiting center. Trimethobenzamide is often used for short-term relief of these symptoms, such as after surgery or due to illness. It can be used alone or with other treatments, depending on your specific condition and doctor's recommendations.
Directions for Use
For how long do I take Trimethobenzamide?
Trimethobenzamide is usually used for short-term relief of nausea and vomiting. The duration of use depends on your symptoms and doctor's advice. It's not typically used for long-term treatment. Always follow your doctor's instructions regarding how long to take Trimethobenzamide. If your symptoms persist or worsen, contact your doctor. They can help determine if you need to continue the medication or try a different treatment.
How do I dispose of Trimethobenzamide?
To dispose of Trimethobenzamide, take it to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of it properly to prevent harm to people or the environment. If you can't find a take-back program, you can throw it in the trash at home. First, mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and then throw it away.
How do I take Trimethobenzamide?
Trimethobenzamide is usually taken three or four times a day. You can take it with or without food, but taking it with food may help reduce stomach upset. Swallow the capsule whole; do not crush or chew it. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not double up on doses. Always follow your doctor's specific instructions regarding the use of this medication.
How long does it take for Trimethobenzamide to start working?
Trimethobenzamide usually starts working within 20 to 30 minutes after taking it. The full therapeutic effect can be felt within an hour. Individual factors like your metabolism and the severity of your symptoms can affect how quickly you notice relief. If you don't experience improvement in your symptoms after taking Trimethobenzamide, contact your doctor. They can assess your condition and determine if any adjustments to your treatment are needed.
How should I store Trimethobenzamide?
Store Trimethobenzamide at room temperature, away from moisture and light. Keep it in a tightly closed container to protect it from damage. Avoid storing it in humid places like bathrooms, where moisture in the air could affect how well the medication works. Always store Trimethobenzamide out of children's reach to prevent accidental swallowing. Check the expiration date regularly and properly dispose of any unused or expired medication.
What is the usual dose of Trimethobenzamide?
The usual dose of Trimethobenzamide for adults is 300 mg taken three or four times a day. The frequency of administration depends on your specific condition and doctor's instructions. There are no specific dose adjustments for children or the elderly, but your doctor may adjust the dose based on your response and any side effects. Always follow your doctor's specific dosing instructions for your personal health needs.
Warnings and Precautions
Can I take Trimethobenzamide with other prescription drugs?
Trimethobenzamide can interact with other medications that cause drowsiness, such as sedatives, antihistamines, and certain pain relievers. These interactions can increase drowsiness and affect your ability to drive or operate machinery. Always inform your doctor about all the medications you're taking to avoid potential interactions. Your doctor can help determine if Trimethobenzamide is safe to use with your other medications and adjust your treatment plan if needed.
Can Trimethobenzamide be taken safely while breastfeeding?
The safety of Trimethobenzamide while breastfeeding is not well-established. It's unclear if this medication passes into breast milk or affects milk supply. If you're breastfeeding or planning to breastfeed, talk with your doctor about the risks and benefits. They can help determine if Trimethobenzamide is safe for you and your baby or suggest alternative treatments that allow you to nurse safely.
Can Trimethobenzamide be taken safely while pregnant?
The safety of Trimethobenzamide during pregnancy is not well-established. Limited data is available, so it's important to weigh the benefits and risks with your doctor. If you're pregnant or planning to become pregnant, discuss your options with your healthcare provider. They can help determine the safest way to manage your symptoms during pregnancy and create a treatment plan that protects both you and your baby.
Does Trimethobenzamide have adverse effects?
Adverse effects are unwanted reactions that can occur with medication use. Common adverse effects of Trimethobenzamide include drowsiness, dizziness, and headache. These effects are usually mild. Serious adverse effects are rare but can include confusion or severe drowsiness. If you experience any severe or unusual symptoms, contact your doctor immediately. Always inform your healthcare provider about any new or worsening symptoms while taking Trimethobenzamide.
Does Trimethobenzamide have any safety warnings?
Trimethobenzamide has some safety warnings you should be aware of. It may cause drowsiness, which can affect your ability to drive or operate machinery. Avoid alcohol, as it can increase drowsiness. If you experience symptoms like confusion, severe drowsiness, or unusual behavior, seek medical attention. These could be signs of a serious reaction. Always follow your doctor's instructions and report any unusual symptoms while taking this medication.
Is it safe to drink alcohol while taking Trimethobenzamide?
It's best to avoid alcohol while taking Trimethobenzamide. Alcohol can increase the drowsiness caused by this medication, which may affect your ability to drive or operate machinery. Drinking alcohol can also worsen side effects like dizziness. If you choose to drink occasionally, limit your alcohol intake and be cautious of any increased drowsiness or dizziness. Talk with your doctor about alcohol use while taking Trimethobenzamide for personalized advice.
Is it safe to exercise while taking Trimethobenzamide?
You can exercise while taking Trimethobenzamide, but be cautious. This medication can cause drowsiness or dizziness, which might affect your balance and coordination during physical activity. If you feel dizzy or lightheaded, avoid strenuous activities or high-impact sports. To exercise safely, start with light activities and see how your body responds. If you notice any unusual symptoms, slow down or stop exercising and rest. Talk with your doctor if you have concerns.
Is it safe to stop Trimethobenzamide?
Trimethobenzamide is typically used for short-term relief of nausea and vomiting. It's safe to stop taking it once your symptoms improve, but always follow your doctor's advice. Stopping the medication suddenly shouldn't cause withdrawal symptoms. However, if your symptoms return or worsen after stopping, contact your doctor. They can help determine if you need to restart the medication or try a different treatment.
Is Trimethobenzamide addictive?
Trimethobenzamide is not considered addictive or habit-forming. It does not cause dependency or withdrawal symptoms when you stop taking it. This medication works by affecting the brain's vomiting center to help control nausea and vomiting. It doesn't affect brain chemistry in ways that could lead to addiction. If you have concerns about medication dependence, you can feel confident that Trimethobenzamide doesn't carry this risk while managing your condition.
Is Trimethobenzamide safe for the elderly?
The elderly may be more sensitive to the side effects of Trimethobenzamide, such as drowsiness and dizziness. These effects can increase the risk of falls or accidents. It's important for older adults to use this medication with caution and under a doctor's supervision. If you're elderly and taking Trimethobenzamide, your doctor may adjust your dose or monitor you more closely to ensure your safety.
What are the most common side effects of Trimethobenzamide?
Side effects are unwanted reactions that can happen when taking a medication. Common side effects of Trimethobenzamide include drowsiness, dizziness, and headache. These effects are usually mild and may go away on their own. If you notice new symptoms after starting Trimethobenzamide, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking Trimethobenzamide?
Do not use Trimethobenzamide if you are allergic to it or its ingredients. Serious allergic reactions, which cause rash, hives, or swelling that makes breathing difficult, require immediate medical help. This medication is not recommended for children under two years old due to the risk of serious side effects. Always inform your doctor about any allergies or medical conditions before starting Trimethobenzamide. They can help determine if this medication is safe for you.
