Trihexyphenidyl
Drug-Induced Abnormalities, Parkinson Disease
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
YES
Known Teratogen
NO
Pharmaceutical Class
undefined
Controlled Drug Substance
No
trihexyphenidyl
Summary
Trihexyphenidyl is used to treat symptoms of Parkinson's disease, which is a disorder affecting movement, and drug-induced movement disorders, which are unwanted movements caused by certain medications.
Trihexyphenidyl works by blocking nerve impulses that cause muscle stiffness and tremors, which are involuntary shaking movements, helping improve muscle control and reduce symptoms.
Trihexyphenidyl is usually taken by mouth, 1 to 4 times a day, with or without food. The starting dose is often 1 mg to 2 mg, adjusted by the doctor as needed.
Common side effects of Trihexyphenidyl include dry mouth, which is a lack of saliva, blurred vision, which is unclear sight, and dizziness, which is a feeling of unsteadiness.
Trihexyphenidyl should not be used by people with narrow-angle glaucoma, which is increased eye pressure, or those allergic to it. Avoid alcohol, as it can increase side effects.
Indications and Purpose
How does Trihexyphenidyl work?
Trihexyphenidyl works by blocking certain nerve impulses that cause muscle stiffness and tremors. Think of it like turning down the volume on a radio to reduce noise. This action helps improve muscle control and reduce symptoms of Parkinson's disease and drug-induced movement disorders. It allows for smoother and more controlled movements.
Is Trihexyphenidyl effective?
Yes, Trihexyphenidyl is effective for treating symptoms of Parkinson's disease and drug-induced movement disorders. It works by blocking certain nerve impulses that cause muscle stiffness and tremors. Clinical studies support its effectiveness in improving muscle control and reducing symptoms. Always follow your doctor's instructions to achieve the best results.
What is Trihexyphenidyl?
Trihexyphenidyl is a medication used to treat symptoms of Parkinson's disease and drug-induced movement disorders. It belongs to a class of drugs called anticholinergics, which work by blocking certain nerve impulses that cause muscle stiffness and tremors. This helps improve muscle control and reduce symptoms. Trihexyphenidyl is often used alongside other therapies for better results.
Directions for Use
For how long do I take Trihexyphenidyl?
Trihexyphenidyl is usually taken long-term for managing chronic conditions like Parkinson's disease. The duration depends on your response and any side effects. Your doctor will guide you on how long to continue the medication. Always consult your doctor before making any changes to your treatment plan.
How do I dispose of Trihexyphenidyl?
Dispose of Trihexyphenidyl by taking it to a drug take-back program or collection site at a pharmacy or hospital. If that's not possible, mix the medication with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away in the trash. This helps prevent harm to people and the environment.
How do I take Trihexyphenidyl?
Take Trihexyphenidyl as prescribed by your doctor. It's usually taken 1 to 4 times a day, either with or without food. You can crush the tablet if needed. If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Don't take two doses at once. Avoid alcohol while on this medication, as it can increase side effects. Always follow your doctor's specific instructions regarding diet and fluid intake while taking Trihexyphenidyl.
How long does it take for Trihexyphenidyl to start working?
Trihexyphenidyl starts working within an hour of taking it, but the full therapeutic effect may take a few days to become noticeable. Individual factors like age, overall health, and the severity of symptoms can affect how quickly you notice improvements. Take it exactly as prescribed for the best results.
How should I store Trihexyphenidyl?
Store Trihexyphenidyl at room temperature, away from moisture and light. Keep it in a tightly closed container. Avoid storing it in humid places like bathrooms, as moisture can affect its effectiveness. Always keep it out of reach of children to prevent accidental ingestion. Check the expiration date regularly and dispose of any unused or expired medication properly.
What is the usual dose of Trihexyphenidyl?
The usual starting dose of Trihexyphenidyl for adults is 1 mg to 2 mg taken once or twice daily. Your doctor may adjust the dose based on your response and needs, up to a maximum of 15 mg per day. For elderly patients, the dose may be lower to reduce the risk of side effects. Always follow your doctor's specific dosing instructions for your health needs.
Warnings and Precautions
Can I take Trihexyphenidyl with other prescription drugs?
Trihexyphenidyl can interact with other medications, increasing the risk of side effects. For example, combining it with other anticholinergic drugs can intensify effects like dry mouth and blurred vision. It may also interact with medications for mental health, affecting their effectiveness. Always inform your doctor about all the medications you're taking to avoid harmful interactions.
Can Trihexyphenidyl be taken safely while breastfeeding?
The safety of Trihexyphenidyl while breastfeeding is not well-established. It's unclear if the medication passes into breast milk or affects milk supply. If you're breastfeeding, discuss with your doctor whether to continue the medication. They can help weigh the benefits and risks and suggest safer alternatives if needed.
Can Trihexyphenidyl be taken safely while pregnant?
Trihexyphenidyl's safety during pregnancy is not well-established. Limited evidence makes it difficult to provide definitive advice. Animal studies suggest potential risks, but human data is lacking. If you're pregnant or planning to become pregnant, talk with your doctor about the safest treatment options. Your doctor can help create a plan that protects both you and your baby.
Does Trihexyphenidyl have adverse effects?
Yes, Trihexyphenidyl can have adverse effects, which are unwanted reactions to a medication. Common adverse effects include dry mouth, blurred vision, and dizziness. These occur in a significant number of users. Serious side effects, like confusion or hallucinations, are less common but require immediate medical attention. If you notice any new or worsening symptoms, contact your doctor promptly.
Does Trihexyphenidyl have any safety warnings?
Yes, Trihexyphenidyl has important safety warnings. It can cause dry mouth, blurred vision, and dizziness, which may affect your ability to drive or operate machinery. It may also cause confusion, especially in the elderly. Not adhering to these warnings can lead to accidents or worsening of symptoms. Always follow your doctor's advice and report any unusual symptoms immediately.
Is it safe to drink alcohol while taking Trihexyphenidyl?
It's best to avoid alcohol while taking Trihexyphenidyl. Alcohol can increase the risk of side effects like dizziness and drowsiness. These symptoms can impair your ability to perform tasks that require alertness. If you choose to drink, limit your intake and be aware of any warning signs. Talk with your doctor for personalized advice.
Is it safe to exercise while taking Trihexyphenidyl?
Yes, you can exercise while taking Trihexyphenidyl, but be cautious. The medication can cause dizziness or blurred vision, which might affect your balance. Start with light activities and gradually increase intensity. Stay hydrated and listen to your body. If you feel dizzy or unwell, stop exercising and rest. Consult your doctor for personalized advice.
Is it safe to stop Trihexyphenidyl?
It's important to consult your doctor before stopping Trihexyphenidyl. This medication is often used for long-term management of conditions like Parkinson's disease. Stopping suddenly can worsen symptoms or cause withdrawal effects. Your doctor may suggest gradually reducing the dose to avoid complications. Always follow your doctor's guidance when making changes to your medication regimen.
Is Trihexyphenidyl addictive?
Trihexyphenidyl is not considered addictive or habit-forming. It doesn't cause dependency or withdrawal symptoms when you stop taking it. However, some people might misuse it for its mood-altering effects. To prevent misuse, take Trihexyphenidyl exactly as prescribed by your doctor. If you have concerns about dependence, discuss them with your healthcare provider.
Is Trihexyphenidyl safe for the elderly?
Trihexyphenidyl can be used by the elderly, but with caution. Older adults are more vulnerable to side effects like confusion, dizziness, and dry mouth. These can increase the risk of falls or accidents. Doctors may prescribe a lower dose to minimize risks. Regular monitoring is important to ensure safety and effectiveness.
What are the most common side effects of Trihexyphenidyl?
Common side effects of Trihexyphenidyl include dry mouth, blurred vision, and dizziness. These are unwanted reactions that can happen when taking the medication. The frequency of these side effects varies, but they are generally not severe. If you experience new symptoms after starting Trihexyphenidyl, they might be temporary or unrelated to the medication. Always talk with your doctor before stopping any medication.
Who should avoid taking Trihexyphenidyl?
Trihexyphenidyl should not be used if you have a known allergy to it. It's also contraindicated in people with narrow-angle glaucoma, which is a condition where fluid pressure in the eye increases. Caution is needed for those with heart disease or high blood pressure. Always consult your doctor to ensure Trihexyphenidyl is safe for you.
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