Triclabendazole
NA
Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
YES
Known Teratogen
No
Pharmaceutical Class
Anthelmintic
Controlled Drug Substance
No

triclabendazole
Summary
Triclabendazole is used to treat infections caused by liver flukes, which are parasites that infect the liver. These infections can cause symptoms like abdominal pain and jaundice, which is yellowing of the skin and eyes.
Triclabendazole works by disrupting the metabolism of liver flukes, which are parasites that infect the liver. It interferes with the parasites' energy production, leading to their death and helping to clear the infection from the body.
The usual dose of Triclabendazole for adults is a single dose of 10 mg/kg, taken with food. For children, the dose is also based on body weight. It's usually taken as a single dose to improve absorption.
Common side effects of Triclabendazole include nausea, vomiting, and abdominal pain, which are usually mild and temporary. If you notice new symptoms after starting Triclabendazole, they might be temporary or unrelated to the medication.
Triclabendazole can cause liver problems, so your doctor may monitor your liver function. Don't take it if you're allergic to it or its ingredients. Serious allergic reactions require immediate medical help. Avoid alcohol, as it can increase the risk of liver problems.
Indications and Purpose
How does Triclabendazole work?
Triclabendazole works by disrupting the metabolism of liver flukes, which are parasites that infect the liver. It interferes with the parasites' energy production, leading to their death. This action helps clear the infection from your body.
Is Triclabendazole effective?
Triclabendazole is effective in treating infections caused by liver flukes, which are parasites that infect the liver. Clinical studies show it successfully clears these infections in most patients. It's important to take the medication as prescribed to achieve the best results.
What is Triclabendazole?
Triclabendazole is an antiparasitic medication used to treat infections caused by liver flukes, which are parasites that infect the liver. It works by disrupting the metabolism of the parasites, leading to their death. This medication is specifically used for treating liver fluke infections and is not typically used for other conditions.
Directions for Use
For how long do I take Triclabendazole?
Triclabendazole is usually taken as a single dose for treating liver fluke infections. The duration of treatment is short-term, and you typically don't need to take it long-term. Always follow your doctor's instructions for the best results.
How do I dispose of Triclabendazole?
If you can, bring unused Triclabendazole to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of this medicine properly so it doesn't harm people or the environment. If you can't find a take-back program, you can throw most medicines in the trash at home. But first, take them out of their original containers, mix them with something undesirable like used coffee grounds, seal the mixture in a plastic bag, and throw it away.
How do I take Triclabendazole?
Take Triclabendazole as directed by your doctor. It's usually taken as a single dose with food to improve absorption. If you have trouble swallowing, you can crush the tablet and mix it with a small amount of water. If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. Don't take two doses at once. Always follow your doctor's specific instructions.
How long does it take for Triclabendazole to start working?
Triclabendazole starts working shortly after you take it, with effects noticeable within a few days. The full therapeutic effect, which is the complete clearance of the infection, may take a few weeks. Individual factors like the severity of the infection can affect how quickly you notice improvements.
How should I store Triclabendazole?
Store Triclabendazole at room temperature, away from moisture and light. Keep it in a tightly closed container. Don't store it in humid places like bathrooms. Always keep it out of reach of children to prevent accidental swallowing.
What is the usual dose of Triclabendazole?
The usual dose of Triclabendazole for adults is a single dose of 10 mg/kg, taken with food. For children, the dose is also based on body weight. Your doctor may adjust the dose based on your specific needs. Always follow your doctor's dosing instructions carefully.
Warnings and Precautions
Can I take Triclabendazole with other prescription drugs?
Triclabendazole has no major drug interactions, but always inform your doctor about all medications you're taking. This helps prevent potential interactions and ensures your treatment is safe and effective.
Can Triclabendazole be taken safely while breastfeeding?
The safety of Triclabendazole while breastfeeding isn't well-established. It's unclear if the medication passes into breast milk. If you're breastfeeding, talk with your doctor about the safest treatment options for you and your baby.
Can Triclabendazole be taken safely while pregnant?
The safety of Triclabendazole during pregnancy isn't well-established. Animal studies suggest potential risks, but human data is limited. If you're pregnant or planning to become pregnant, talk with your doctor about the safest treatment options.
Does Triclabendazole have adverse effects?
Adverse effects are unwanted reactions to a medication. Triclabendazole can cause side effects like nausea, vomiting, and abdominal pain, which are usually mild. Serious side effects are rare but can include liver problems. If you notice any new or worsening symptoms, contact your doctor immediately.
Does Triclabendazole have any safety warnings?
Triclabendazole has safety warnings you should know about. It can cause liver problems, so your doctor may monitor your liver function. If you experience symptoms like yellowing of the skin or eyes, dark urine, or severe abdominal pain, seek medical help. Not adhering to these warnings can lead to serious health issues.
Is it safe to drink alcohol while taking Triclabendazole?
It's best to avoid alcohol while taking Triclabendazole. Alcohol can increase the risk of liver problems, which is a concern with this medication. If you do choose to drink, limit your alcohol intake and talk with your doctor for personalized advice.
Is it safe to exercise while taking Triclabendazole?
You can exercise while taking Triclabendazole, but be mindful of how you feel. This medication can cause stomach upset, which might affect your exercise routine. If you feel unwell, slow down or stop exercising and rest. Talk with your doctor if you have concerns.
Is it safe to stop Triclabendazole?
Triclabendazole is usually taken as a single dose for treating infections, so there's no long-term use. If you have concerns about stopping the medication, talk with your doctor. They can provide guidance based on your specific health needs.
Is Triclabendazole addictive?
Triclabendazole is not addictive or habit-forming. This medication doesn't cause dependency or withdrawal symptoms when you stop taking it. You won't experience cravings for this medication or feel compelled to take more than prescribed. If you have concerns about medication dependence, you can feel confident that Triclabendazole doesn't carry this risk.
Is Triclabendazole safe for the elderly?
Elderly individuals may be more vulnerable to side effects from medications. Triclabendazole is generally safe for the elderly, but they should be monitored for liver function and any adverse reactions. Always consult a doctor for personalized advice.
What are the most common side effects of Triclabendazole?
Side effects are unwanted reactions that can happen when taking a medication. Common side effects of Triclabendazole include nausea, vomiting, and abdominal pain. These effects are usually mild and temporary. If you notice new symptoms after starting Triclabendazole, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking Triclabendazole?
Don't take Triclabendazole if you're allergic to it or its ingredients. Serious allergic reactions, which cause rash, hives, or swelling that makes breathing difficult, require immediate medical help. Always consult your doctor about any concerns.