Tivozanib
Renal Cell Carcinoma
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Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Kinase Inhibitor
Controlled Drug Substance
No
Summary
Tivozanib is used to treat renal cell carcinoma, which is a type of kidney cancer. It helps slow the progression of cancer and is often part of a comprehensive treatment plan for patients with advanced kidney cancer.
Tivozanib works by inhibiting tyrosine kinases, which are proteins that promote cancer growth. By blocking these proteins, it helps slow down the progression of cancer, particularly effective in treating renal cell carcinoma.
The usual starting dose of Tivozanib for adults is 1.34 mg once daily, taken orally. Your doctor may adjust your dose based on your response and any side effects, with a maximum recommended dose of 1.5 mg daily.
Common side effects of Tivozanib include high blood pressure, fatigue, and diarrhea. These effects vary in frequency and severity, and it's important to inform your doctor about any new or worsening symptoms.
Tivozanib can increase the risk of high blood pressure and heart problems. It's not recommended for people with severe liver issues or during pregnancy and breastfeeding. Always consult your doctor about any concerns before starting Tivozanib.
Indications and Purpose
How does Tivozanib work?
Tivozanib works by inhibiting certain proteins called tyrosine kinases, which are involved in the growth and spread of cancer cells. Think of it like turning off a switch that powers cancer growth. By blocking these proteins, Tivozanib helps slow down the progression of cancer. This medication is particularly effective in treating renal cell carcinoma, a type of kidney cancer, by targeting the pathways that cancer cells use to grow.
Is Tivozanib effective?
Tivozanib is effective in treating certain types of cancer, such as renal cell carcinoma, which is a type of kidney cancer. It works by inhibiting proteins that promote cancer growth. Clinical studies show Tivozanib can improve progression-free survival in patients with this cancer. Your doctor will monitor your response to the medication to ensure it's working effectively for your condition.
What is Tivozanib?
Tivozanib is a medication used to treat renal cell carcinoma, which is a type of kidney cancer. It belongs to a class of drugs called tyrosine kinase inhibitors, which work by blocking proteins that promote cancer growth. Tivozanib helps slow the progression of cancer and is used as a treatment option for patients with advanced kidney cancer. It is usually part of a comprehensive cancer treatment plan.
Directions for Use
For how long do I take Tivozanib?
Tivozanib is usually a long-term medication for managing certain types of cancer, like renal cell carcinoma. You'll typically take Tivozanib every day as part of your cancer treatment plan unless your doctor suggests otherwise. How long you'll need this medication depends on your body's response, any side effects you experience, and changes in your overall health. Always talk with your doctor before changing or stopping your Tivozanib treatment.
How do I dispose of Tivozanib?
If you can, bring unused Tivozanib to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of this medicine properly so it doesn't harm people or the environment. If you can't find a take-back program, you can throw most medicines in the trash at home. But first, take them out of their original containers, mix them with something undesirable like used coffee grounds, seal the mixture in a plastic bag, and throw it away.
How do I take Tivozanib?
Take Tivozanib as prescribed by your doctor, usually once daily. You can take it with or without food. Do not crush or chew the capsule. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not take two doses at once. Follow your doctor's advice on any dietary or beverage restrictions while on this medication.
How long does it take for Tivozanib to start working?
Tivozanib begins working in your body shortly after you take it, but the full therapeutic effects may take several weeks to become noticeable. The time it takes to see results can vary based on individual factors like your overall health and the stage of your cancer. Regular check-ups with your doctor will help monitor your progress and determine how well Tivozanib is working for your condition.
How should I store Tivozanib?
Store Tivozanib at room temperature, away from moisture and light. Keep it in a tightly closed container to protect it from damage. Don't store your medicine in humid places like bathrooms, where moisture in the air could affect how well the medication works. Always store Tivozanib out of children's reach to prevent accidental swallowing. Check the expiration date regularly and properly dispose of any unused or expired medication.
What is the usual dose of Tivozanib?
The usual starting dose of Tivozanib for adults is 1.34 mg once daily. Your doctor may adjust your dose based on your response and any side effects. The maximum recommended dose is 1.5 mg daily. Always follow your doctor's specific dosing instructions for your health needs. Special populations, such as the elderly, may require careful monitoring and dose adjustments.
Warnings and Precautions
Can Tivozanib be taken safely while breastfeeding?
Tivozanib is not recommended while breastfeeding. We don't have much information about whether this medication passes into human breast milk. However, it may pose risks to a nursing infant. If you're taking Tivozanib and want to breastfeed, talk with your doctor about safer medication options that would allow you to nurse your baby safely.
Can Tivozanib be taken safely while pregnant?
Tivozanib is not recommended during pregnancy. It may harm an unborn baby. We don't have much information about Tivozanib use in pregnant women, but animal studies suggest potential risks. If you're pregnant or planning to become pregnant, talk with your doctor about the safest way to manage your condition. Your doctor can help create a treatment plan that protects both you and your baby.
Does Tivozanib have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Tivozanib include high blood pressure, fatigue, and diarrhea. These effects vary in frequency and severity. Serious side effects, like liver problems or heart issues, require immediate medical attention. Always inform your doctor about any new or worsening symptoms while taking Tivozanib to ensure safe and effective treatment.
Does Tivozanib have any safety warnings?
Yes, Tivozanib has important safety warnings. It can increase the risk of high blood pressure and heart problems. Monitor your blood pressure regularly while taking this medication. Tivozanib may also cause liver problems, so watch for symptoms like yellowing of the skin or eyes. If you experience any severe side effects, contact your doctor immediately. Adhering to safety warnings helps prevent serious health issues.
Is it safe to drink alcohol while taking Tivozanib?
It's best to avoid alcohol while taking Tivozanib. Alcohol can increase the risk of liver problems, which Tivozanib may also cause. Drinking alcohol might worsen side effects like dizziness or nausea. If you do choose to drink occasionally, limit how much alcohol you consume and watch for warning signs like fatigue or stomach pain. Talk with your doctor about alcohol use while taking Tivozanib for personalized advice.
Is it safe to exercise while taking Tivozanib?
You can exercise while taking Tivozanib, but keep a few things in mind. This medication can cause fatigue, which might affect your exercise capacity. Listen to your body and avoid strenuous activities if you feel tired. Stay hydrated, as Tivozanib can increase urination. If you notice dizziness or unusual fatigue during exercise, slow down or stop and rest. Check with your doctor if you have concerns about your specific situation.
Is it safe to stop Tivozanib?
Stopping Tivozanib suddenly can affect your treatment. If you're taking it for cancer, stopping could allow the cancer to progress. Always talk with your doctor before stopping Tivozanib. They might suggest gradually reducing your dose or switching to a different medication to keep your condition under control. Your doctor will help you make any medication changes safely to protect your health.
Is Tivozanib addictive?
Tivozanib is not addictive or habit-forming. This medication doesn't cause dependency or withdrawal symptoms when you stop taking it. Tivozanib works by inhibiting certain proteins involved in cancer growth, and this mechanism doesn't affect brain chemistry in ways that could lead to addiction. You won't experience cravings for this medication or feel compelled to take more than prescribed.
What are the most common side effects of Tivozanib?
Side effects are unwanted reactions that can happen when taking a medication. Common side effects of Tivozanib include high blood pressure, fatigue, and diarrhea. These effects vary from person to person. If you notice new symptoms after starting Tivozanib, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking Tivozanib?
Don't take Tivozanib if you're allergic to it or its ingredients. Serious allergic reactions require immediate medical help. Tivozanib is not recommended for people with severe liver problems, as it may worsen liver function. Pregnant or breastfeeding women should avoid this medication due to potential harm to the baby. Always consult your doctor about any concerns or conditions before starting Tivozanib.
