Ticagrelor
.svg)
Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
YES
Known Teratogen
NO
Pharmaceutical Class
None
Controlled Drug Substance
NO
Ticagrelor
Summary
Ticagrelor is used to prevent blood clots in people with acute coronary syndrome, which is a condition where the blood supply to the heart is suddenly blocked. It helps reduce the risk of heart attack, stroke, and cardiovascular death.
Ticagrelor works by blocking a receptor on platelets, which are cells that help blood clot. This prevents platelets from sticking together and forming clots, reducing the risk of heart attacks and strokes.
The usual starting dose of Ticagrelor for adults is 90 mg taken twice daily. It can be taken with or without food. Swallow the tablet whole without crushing or chewing it.
Common side effects of Ticagrelor include bleeding, shortness of breath, and dizziness. These effects vary from person to person and should be discussed with a doctor if they occur.
Ticagrelor can increase the risk of bleeding and is contraindicated in people with active bleeding or a history of intracranial hemorrhage, which is bleeding in the brain. Avoid grapefruit juice as it can interact with the medication.
Indications and Purpose
How does Ticagrelor work?
Ticagrelor works by blocking a receptor on platelets, which are cells that help blood clot. This prevents platelets from sticking together and forming clots. Think of it like putting a barrier between two magnets to stop them from sticking. By reducing clot formation, Ticagrelor helps prevent heart attacks and strokes in people with certain heart conditions.
Is Ticagrelor effective?
Ticagrelor is effective in preventing blood clots in people with certain heart conditions. It works by inhibiting platelets, which are cells that help blood clot. Clinical studies show Ticagrelor reduces the risk of heart attack, stroke, and cardiovascular death. It's important to take Ticagrelor as prescribed by your doctor to achieve the best results.
What is Ticagrelor?
Ticagrelor is a medication that belongs to a class called antiplatelet drugs. It works by preventing blood clots, which can reduce the risk of heart attack and stroke. Ticagrelor is primarily used to treat people with acute coronary syndrome, which is a condition where the blood supply to the heart is suddenly blocked. It may also be used in other heart-related conditions as prescribed by a doctor.
Directions for Use
For how long do I take Ticagrelor?
Ticagrelor is usually a long-term medication for managing heart conditions. You'll typically take it every day as a lifelong treatment unless your doctor suggests otherwise. Stopping this medication without medical advice could increase your risk of heart attack or stroke. Always talk with your doctor before changing or stopping your Ticagrelor treatment.
How do I dispose of Ticagrelor?
Dispose of Ticagrelor by taking it to a drug take-back program or collection site at a pharmacy or hospital. If you can't find a take-back program, you can throw it in the trash at home. First, mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away.
How do I take Ticagrelor?
Take Ticagrelor as prescribed by your doctor, usually twice daily. You can take it with or without food. Swallow the tablet whole; do not crush or chew it. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not take two doses at once. Avoid grapefruit juice, as it can interact with Ticagrelor.
How long does it take for Ticagrelor to start working?
Ticagrelor begins working shortly after you take it, with its effects starting within 30 minutes. However, the full therapeutic effect, such as reducing the risk of heart attack or stroke, may take longer to observe. It's important to take Ticagrelor exactly as prescribed for the best results. Your doctor will monitor your progress and adjust your treatment as needed.
How should I store Ticagrelor?
Store Ticagrelor at room temperature, away from moisture and light. Keep it in a tightly closed container. Don't store it in humid places like bathrooms. If your pills came in packaging that isn't child-resistant, transfer them to a container that children can't easily open. Always store Ticagrelor out of children's reach.
What is the usual dose of Ticagrelor?
The usual starting dose of Ticagrelor for adults is 90 mg twice daily. Your doctor may adjust the dose based on your specific health needs. It's important to follow your doctor's instructions carefully. For elderly patients or those with certain health conditions, dose adjustments may be necessary. Always consult your doctor for personalized dosing guidance.
Warnings and Precautions
Can I take Ticagrelor with other prescription drugs?
Ticagrelor can interact with certain medications, increasing the risk of bleeding. Avoid using it with other blood thinners unless directed by your doctor. Some antifungal and antibiotic medications can also interact with Ticagrelor. Always inform your doctor about all medications you take to prevent interactions and ensure safe treatment.
Can Ticagrelor be taken safely while breastfeeding?
Ticagrelor is not recommended while breastfeeding due to limited safety data. It's unclear if Ticagrelor passes into breast milk or affects milk production. If you're taking Ticagrelor and want to breastfeed, talk with your doctor about safer medication options that would allow you to nurse your baby safely.
Can Ticagrelor be taken safely while pregnant?
Ticagrelor is not recommended during pregnancy due to limited safety data. Animal studies suggest potential risks, but human data is lacking. If you're pregnant or planning to become pregnant, talk with your doctor about the safest way to manage your condition. Your doctor can help create a treatment plan that protects both you and your baby.
Does Ticagrelor have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Ticagrelor include bleeding and shortness of breath. Serious side effects can occur, such as severe bleeding or allergic reactions. If you notice any new or worsening symptoms, contact your doctor immediately. They can help determine if the symptoms are related to Ticagrelor and provide appropriate care.
Does Ticagrelor have any safety warnings?
Yes, Ticagrelor has important safety warnings. It can increase the risk of bleeding, which can be serious. If you experience unusual bleeding or bruising, seek medical help immediately. Ticagrelor can also cause shortness of breath. If you have breathing problems, contact your doctor. It's crucial to follow your doctor's instructions and report any side effects promptly.
Is it safe to drink alcohol while taking Ticagrelor?
It's best to avoid alcohol while taking Ticagrelor. Alcohol can increase the risk of bleeding, which is a side effect of Ticagrelor. If you choose to drink occasionally, limit your alcohol intake and watch for signs of bleeding, such as unusual bruising or bleeding gums. Talk with your doctor about alcohol use while taking Ticagrelor.
Is it safe to exercise while taking Ticagrelor?
You can exercise while taking Ticagrelor, but be cautious. This medication can increase the risk of bleeding, so avoid activities with a high risk of injury. If you feel dizzy or lightheaded during exercise, stop and rest. Drink plenty of water and monitor for any unusual symptoms. Consult your doctor if you have concerns about your exercise routine.
Is it safe to stop Ticagrelor?
Stopping Ticagrelor suddenly can increase your risk of blood clots, which can lead to heart attack or stroke. Always talk with your doctor before stopping Ticagrelor. They might suggest gradually reducing your dose or switching to a different medication to keep your condition under control. Your doctor will help you make any medication changes safely.
Is Ticagrelor addictive?
Ticagrelor is not addictive or habit-forming. It doesn't cause dependency or withdrawal symptoms when you stop taking it. Ticagrelor works by preventing blood clots, which doesn't affect brain chemistry in ways that could lead to addiction. You won't experience cravings for this medication or feel compelled to take more than prescribed.
Is Ticagrelor safe for the elderly?
About half the people in the study were 65 or older, and a good chunk of those were 75 or older. The study found that the medicine worked about the same and was equally safe for both older and younger people.
What are the most common side effects of Ticagrelor?
Side effects are unwanted reactions to a medication. Common side effects of Ticagrelor include bleeding, shortness of breath, and dizziness. These effects vary from person to person. If you notice new symptoms after starting Ticagrelor, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking Ticagrelor?
Don't take Ticagrelor if you're allergic to it or its ingredients. It's contraindicated in people with active bleeding or a history of intracranial hemorrhage, which is bleeding in the brain. Use caution if you have liver problems. Always consult your doctor about these concerns before starting Ticagrelor.
Forms / Brands
