Teriparatide

Postmenopausal Osteoporosis

Drug Status

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Government Approvals

US(FDA), UK(BNF)

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WHO Essential Medicine

NO

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Known Teratogen

No

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Pharmaceutical Class

Parathyroid Hormone Analog

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Controlled Drug Substance

No

Summary

  • Teriparatide is used to treat osteoporosis, which is a condition where bones become weak and brittle. It helps increase bone density and reduce the risk of fractures. Teriparatide is often used in people who have a high risk of fractures or who haven't responded well to other osteoporosis treatments.

  • Teriparatide works by mimicking the effects of parathyroid hormone, which helps regulate calcium levels in the body. It stimulates new bone growth and increases bone density. Think of it like a gardener adding nutrients to soil to help plants grow stronger. This makes bones less likely to fracture.

  • The usual dose of teriparatide for adults is 20 micrograms injected under the skin once a day. It's important to follow your doctor's instructions on how to use it. You can take it with or without food. If you miss a dose, take it as soon as you remember, but don't take two doses at once.

  • Common side effects of teriparatide include nausea, joint pain, and dizziness. These effects vary from person to person and are usually mild. If you notice new symptoms after starting teriparatide, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.

  • Teriparatide has important safety warnings. It may increase the risk of bone cancer, so it's not recommended for people with certain bone disorders. It's also not for people with high levels of calcium in their blood. If you experience symptoms like nausea, vomiting, or muscle weakness, contact your doctor.

Indications and Purpose

How does teriparatide work?

Teriparatide works by mimicking the effects of parathyroid hormone, which helps regulate calcium levels in the body. It stimulates new bone growth and increases bone density. Think of it like a gardener adding nutrients to soil to help plants grow stronger. This makes bones less likely to fracture.

Is teriparatide effective?

Teriparatide is effective for treating osteoporosis, which is a condition where bones become weak and brittle. It works by stimulating new bone growth, increasing bone density, and reducing the risk of fractures. Clinical studies show teriparatide significantly improves bone density and reduces fracture risk in people with osteoporosis.

What is teriparatide?

Teriparatide is a medication used to treat osteoporosis, which is a condition where bones become weak and brittle. It belongs to a class of drugs called parathyroid hormone analogs. Teriparatide works by stimulating new bone growth and increasing bone density, which helps reduce the risk of fractures.

Directions for Use

For how long do I take teriparatide?

Teriparatide is usually used for a limited time, often up to two years, for treating osteoporosis, which is a condition where bones become weak and brittle. Your doctor will determine the duration based on your specific health needs. Always follow your doctor's advice on how long to take this medication.

How do I dispose of teriparatide?

Dispose of unused teriparatide by taking it to a drug take-back program or collection site at a pharmacy or hospital. If you can't find a take-back program, you can throw it in the trash at home. First, take it out of its original container, mix it with something undesirable like used coffee grounds, seal the mixture in a plastic bag, and throw it away.

How do I take teriparatide?

Teriparatide is usually given as an injection under the skin once a day. It's important to follow your doctor's instructions on how to use it. You can take it with or without food. If you miss a dose, take it as soon as you remember, but don't take two doses at once. Always follow your doctor's specific advice about how to take this medication.

How long does it take for teriparatide to start working?

Teriparatide starts working in your body shortly after you begin taking it, but it may take several months to see significant improvements in bone density. The full therapeutic effect can take up to 18 to 24 months. Individual factors like age and overall health can affect how quickly you notice benefits.

How should I store teriparatide?

Store teriparatide in the refrigerator at a temperature between 36°F to 46°F. Keep it in its original container to protect it from light. Don't freeze it. If you travel, use a cooler to keep it cold. Always check the expiration date and properly dispose of any unused or expired medication.

What is the usual dose of teriparatide?

The usual dose of teriparatide for adults is 20 micrograms injected under the skin once a day. It's important to follow your doctor's instructions on how to use it. Your doctor may adjust your dose based on your specific health needs. Always follow your doctor's specific dosing instructions.

Warnings and Precautions

Can I take teriparatide with other prescription drugs?

Teriparatide doesn't have many known drug interactions. However, it's important to tell your doctor about all the medications you're taking. This helps prevent any potential interactions and ensures your treatment is safe and effective. Always follow your doctor's advice regarding medication use.

Can teriparatide be taken safely while breastfeeding?

Teriparatide is not recommended while breastfeeding. There's limited information on whether it passes into human breast milk. Animal studies suggest it might affect the developing infant. If you're breastfeeding and need treatment for osteoporosis, talk with your doctor about safer medication options.

Can teriparatide be taken safely while pregnant?

Teriparatide is not recommended during pregnancy. There's limited evidence on its safety for pregnant women. Animal studies suggest potential risks to the developing fetus. If you're pregnant or planning to become pregnant, talk with your doctor about the safest way to manage your bone health during this time.

Does teriparatide have adverse effects?

Adverse effects are unwanted reactions to a medication. Common adverse effects of teriparatide include nausea, joint pain, and dizziness. These effects are usually mild. A serious but rare adverse effect is an increased risk of bone cancer. If you experience any new or worsening symptoms, contact your doctor. They can help determine if these symptoms are related to teriparatide.

Does teriparatide have any safety warnings?

Yes, teriparatide has important safety warnings. It may increase the risk of bone cancer, so it's not recommended for people with certain bone disorders. It's also not for people with high levels of calcium in their blood. If you experience symptoms like nausea, vomiting, or muscle weakness, contact your doctor. Always follow your doctor's advice and report any unusual symptoms.

Is it safe to drink alcohol while taking teriparatide?

It's best to limit alcohol while taking teriparatide. Alcohol can weaken bones and increase the risk of falls, which is a concern for people with osteoporosis. If you choose to drink, do so in moderation and talk with your doctor about your alcohol use to get personalized advice.

Is it safe to exercise while taking teriparatide?

Yes, you can exercise while taking teriparatide. Exercise is beneficial for bone health, but be cautious. Teriparatide can cause dizziness, so avoid activities that increase your risk of falls. Drink plenty of water and watch for signs of dizziness or fatigue. Talk with your doctor about a safe exercise plan.

Is it safe to stop teriparatide?

Stopping teriparatide suddenly may affect your bone health. It's used for osteoporosis, which is a condition where bones become weak and brittle. Stopping could increase your risk of fractures. Always talk with your doctor before stopping teriparatide. They might suggest a different medication to maintain your bone health.

Is teriparatide addictive?

Teriparatide is not addictive or habit-forming. This medication doesn't cause dependency or withdrawal symptoms when you stop taking it. It works by stimulating bone growth and doesn't affect brain chemistry in ways that could lead to addiction. You won't experience cravings for this medication or feel compelled to take more than prescribed.

Is teriparatide safe for the elderly?

The elderly are more vulnerable to safety risks of medications due to age-related changes in the body. Teriparatide is generally safe for the elderly, but they may experience dizziness or an increased risk of falls. Regular monitoring by a doctor is important to ensure safe use.

What are the most common side effects of teriparatide?

Side effects are unwanted reactions to a medication. Common side effects of teriparatide include nausea, joint pain, and dizziness. These effects vary from person to person and are usually mild. If you notice new symptoms after starting teriparatide, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.

Who should avoid taking teriparatide?

Teriparatide should not be used by people with bone cancer or high levels of calcium in their blood. These are absolute contraindications. It's also not recommended for people with certain bone disorders. Always consult your doctor about any concerns and follow their advice.