Tepotinib

NA

Drug Status

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Government Approvals

US(FDA)

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WHO Essential Medicine

NO

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Known Teratogen

No

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Pharmaceutical Class

Kinase Inhibitor

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Controlled Drug Substance

No

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Drug Ingredient

tepotinib

Summary

  • Tepotinib is used to treat non-small cell lung cancer, which is a type of lung cancer that starts in the cells lining the lungs. It is specifically used when the cancer has certain genetic changes and has spread or cannot be removed by surgery.

  • Tepotinib works by blocking a protein called MET, which helps cancer cells grow. By inhibiting this protein, Tepotinib slows down or stops the growth of cancer cells, helping to control the disease.

  • The usual starting dose of Tepotinib for adults is 450 mg taken once daily. It can be taken with or without food. Always follow your doctor's specific dosing instructions for your personal health needs.

  • Common side effects of Tepotinib include fatigue, which means feeling very tired, and nausea, which is a feeling of sickness in the stomach. Some people may also experience swelling in different parts of the body.

  • Tepotinib can cause serious lung and liver problems. Symptoms include cough, shortness of breath, or fever. It should not be taken if you are allergic to it. Regular liver function tests are recommended to monitor for potential issues.

Indications and Purpose

How does Tepotinib work?

Tepotinib works by blocking a protein called MET, which helps cancer cells grow. Think of it like turning off a switch that cancer cells need to multiply. By inhibiting this protein, Tepotinib slows down or stops the growth of cancer cells, helping to control the disease.

Is Tepotinib effective?

Tepotinib is effective in treating non-small cell lung cancer with specific genetic changes. Clinical studies show Tepotinib can shrink tumors and slow disease progression. Your doctor will monitor your response to the medication through regular check-ups and tests to ensure it's working effectively for your condition.

What is Tepotinib?

Tepotinib is a medication used to treat non-small cell lung cancer with specific genetic changes. It works by blocking a protein that helps cancer cells grow. This medication is part of a class called MET inhibitors, which target cancer cell growth pathways. Tepotinib is used when the cancer has spread or cannot be removed by surgery.

Directions for Use

For how long do I take Tepotinib?

Tepotinib is usually a long-term medication for managing non-small cell lung cancer. You'll typically take Tepotinib every day as a continuous treatment unless your doctor suggests otherwise. How long you'll need this medication depends on your body's response and any side effects you experience. Always talk with your doctor before changing or stopping your Tepotinib treatment.

How do I dispose of Tepotinib?

If you can, bring unused Tepotinib to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of this medicine properly so it doesn't harm people or the environment. If you can't find a take-back program, you can throw most medicines in the trash at home. But first, take them out of their original containers, mix them with something undesirable like used coffee grounds, seal the mixture in a plastic bag, and throw it away.

How do I take Tepotinib?

Tepotinib is usually taken once daily. You can take it with or without food. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not take two doses at once. Always follow your doctor's specific instructions regarding the use of Tepotinib.

How long does it take for Tepotinib to start working?

Tepotinib begins working in your body shortly after you take it, but the full therapeutic effect may take weeks to months. The time it takes to notice benefits can vary based on individual factors like your overall health and how your body responds to the medication. Regular check-ups with your doctor will help monitor its effectiveness.

How should I store Tepotinib?

Store Tepotinib at room temperature, away from moisture and light. Keep it in its original container, tightly closed, and out of reach of children. Do not store it in humid places like bathrooms. Always check the expiration date and properly dispose of any unused or expired medication.

What is the usual dose of Tepotinib?

The usual starting dose of Tepotinib for adults is 450 mg once daily. Your doctor may adjust your dose based on your response to the medication and any side effects you experience. Always follow your doctor's specific dosing instructions for your personal health needs.

Warnings and Precautions

Can I take Tepotinib with other prescription drugs?

Tepotinib can interact with certain medications, increasing the risk of side effects or reducing its effectiveness. Always inform your doctor about all the medications you are taking, including over-the-counter drugs and supplements. Your doctor can help manage any potential interactions to ensure your treatment is safe and effective.

Can Tepotinib be taken safely while breastfeeding?

Tepotinib is not recommended while breastfeeding. There is limited information on whether this medication passes into human breast milk. If you're taking Tepotinib and want to breastfeed, talk with your doctor about safer medication options that would allow you to nurse your baby safely.

Can Tepotinib be taken safely while pregnant?

Tepotinib is not recommended during pregnancy due to potential risks to the unborn baby. There is limited information on its safety in pregnant women. If you're pregnant or planning to become pregnant, talk with your doctor about the safest treatment options for your condition.

Does Tepotinib have adverse effects?

Adverse effects are unwanted reactions to a medication. Common adverse effects of Tepotinib include swelling, fatigue, and nausea. Serious side effects can include lung or liver problems. If you notice any new or worsening symptoms, contact your doctor immediately. Regular monitoring by your healthcare provider can help manage any adverse effects.

Does Tepotinib have any safety warnings?

Tepotinib has important safety warnings. It can cause lung problems, which may be serious. Symptoms include cough, shortness of breath, or fever. If you experience these, contact your doctor immediately. Tepotinib can also cause liver problems, so regular liver function tests are recommended. Always follow your doctor's advice and report any new or worsening symptoms.

Is it safe to drink alcohol while taking Tepotinib?

It's best to avoid alcohol while taking Tepotinib. Alcohol can increase the risk of liver problems, which are a potential side effect of Tepotinib. If you do choose to drink occasionally, limit how much alcohol you consume and talk with your doctor about alcohol use while taking Tepotinib to get personalized advice.

Is it safe to exercise while taking Tepotinib?

You can exercise while taking Tepotinib, but be mindful of your body's response. Tepotinib can cause fatigue, which might affect your exercise capacity. To exercise safely, listen to your body and rest if you feel unusually tired. Talk with your doctor if you have concerns about your specific situation.

Is it safe to stop Tepotinib?

Stopping Tepotinib suddenly can cause your condition to worsen. Always talk with your doctor before stopping Tepotinib. They might suggest gradually reducing your dose or switching to a different medication to keep your condition under control. Your doctor will help you make any medication changes safely to protect your health.

Is Tepotinib addictive?

Tepotinib is not addictive or habit-forming. This medication doesn't cause dependency or withdrawal symptoms when you stop taking it. If you have concerns about medication dependence, you can feel confident that Tepotinib doesn't carry this risk while managing your health condition.

Is Tepotinib safe for the elderly?

Elderly patients may be more vulnerable to side effects of Tepotinib, such as liver problems and fatigue. Regular monitoring by a healthcare provider is important to manage any potential risks. Always consult your doctor about the safety of Tepotinib for elderly patients.

What are the most common side effects of Tepotinib?

Side effects are unwanted reactions that can happen when taking a medication. Common side effects of Tepotinib include swelling, fatigue, and nausea. These effects vary from person to person. If you notice new symptoms after starting Tepotinib, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.

Who should avoid taking Tepotinib?

Don't take Tepotinib if you're allergic to it or its ingredients. Serious allergic reactions require immediate medical help. Tepotinib should be used with caution in patients with liver problems. Always consult your doctor about any concerns and inform them of your medical history before starting Tepotinib.