Tenofovir alafenamide
Chronic Hepatitis B, Acquired Immunodeficiency Syndrome
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
undefined
Controlled Drug Substance
No
Tenofovir alafenamide
Summary
Tenofovir alafenamide is used to treat HIV-1 infection, which is a virus that attacks the immune system. It helps reduce the amount of virus in the body, improving immune function. This medication is part of a complete treatment regimen and is not used alone.
Tenofovir alafenamide works by blocking an enzyme called reverse transcriptase, which the HIV virus needs to multiply. This action reduces the amount of virus in the body, helping to improve immune function and manage HIV infection.
The usual dose of Tenofovir alafenamide for adults is one tablet taken once daily with food. The specific dosage may vary based on individual needs. It's important to follow your doctor's instructions and not to crush or chew the tablets.
Common side effects of Tenofovir alafenamide include nausea, headache, and fatigue, which refer to feeling tired. These effects are usually mild and occur in a small percentage of people. If you notice new symptoms, talk with your doctor.
Tenofovir alafenamide can cause lactic acidosis, which is a buildup of lactic acid in the blood, and severe liver problems. It's not recommended for people with severe kidney issues. Always consult your doctor about any concerns or conditions that might affect your use of this medication.
Indications and Purpose
How does Tenofovir alafenamide work?
Tenofovir alafenamide works by blocking an enzyme called reverse transcriptase, which the HIV virus needs to multiply. This action reduces the amount of virus in the body, helping to improve immune function. Think of it like stopping a copy machine from making more copies. This helps manage HIV infection and improve health.
Is Tenofovir alafenamide effective?
Yes, Tenofovir alafenamide is effective in treating HIV-1 infection. It works by reducing the amount of virus in the body, which helps improve immune function. Clinical studies show that it effectively lowers viral load and increases CD4 cell counts, which are important for a healthy immune system. This medication is a key part of antiretroviral therapy for managing HIV.
What is Tenofovir alafenamide?
Tenofovir alafenamide is an antiretroviral medication used to treat HIV-1 infection. It works by reducing the amount of virus in the body, which helps improve immune function. This medication is often used in combination with other antiretroviral drugs as part of a complete treatment regimen for managing HIV.
Directions for Use
For how long do I take Tenofovir alafenamide?
Tenofovir alafenamide is usually a long-term medication for managing HIV. You'll typically take it every day as a lifelong treatment unless your doctor suggests otherwise. Stopping this medication without medical advice could cause your condition to worsen. Always talk with your doctor before changing or stopping your treatment.
How do I dispose of Tenofovir alafenamide?
Dispose of Tenofovir alafenamide by taking it to a drug take-back program or collection site at a pharmacy or hospital. If you can't find a take-back program, you can throw it in the trash at home. First, mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away. This helps prevent harm to people and the environment.
How do I take Tenofovir alafenamide?
Take Tenofovir alafenamide as prescribed by your doctor, usually once daily. It's best to take it with food to help your body absorb the medicine better. Do not crush or chew the tablets. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue with your regular schedule. Do not take two doses at once.
How long does it take for Tenofovir alafenamide to start working?
Tenofovir alafenamide starts working shortly after you take it, but you may not notice all the benefits right away. It can take several weeks to see significant changes in your viral load and immune function. Regular blood tests will help monitor your progress. Follow your doctor's instructions for the best results.
How should I store Tenofovir alafenamide?
Store Tenofovir alafenamide at room temperature, away from moisture and light. Keep it in a tightly closed container. Don't store it in humid places like bathrooms. Always keep it out of reach of children to prevent accidental swallowing. Check the expiration date regularly and properly dispose of any unused or expired medication.
What is the usual dose of Tenofovir alafenamide?
The usual dose of Tenofovir alafenamide for adults is one tablet taken once daily with food. The specific dosage may vary based on the condition being treated and individual patient needs. Always follow your doctor's specific dosing instructions. Dose adjustments may be necessary for special populations, such as those with kidney problems or the elderly.
Warnings and Precautions
Can I take Tenofovir alafenamide with other prescription drugs?
Tenofovir alafenamide can interact with certain medications, such as other antiviral drugs, which may increase the risk of side effects or reduce effectiveness. Always inform your doctor about all the medications you are taking to avoid potential interactions. Your doctor will help manage any interactions to ensure safe and effective treatment.
Can Tenofovir alafenamide be taken safely while breastfeeding?
Tenofovir alafenamide is generally considered safe while breastfeeding. It does pass into breast milk, but studies show it doesn't harm the baby. However, managing HIV is important to prevent transmission. Always discuss with your doctor before breastfeeding to ensure the best plan for you and your baby.
Can Tenofovir alafenamide be taken safely while pregnant?
Tenofovir alafenamide is generally considered safe during pregnancy, but it's important to discuss with your doctor. Limited data is available, but studies suggest it doesn't harm the baby. Managing HIV during pregnancy is crucial to prevent transmission to the baby. Your doctor will help create a treatment plan that protects both you and your baby.
Does Tenofovir alafenamide have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Tenofovir alafenamide include nausea, headache, and fatigue. These effects are usually mild. Serious adverse effects, like lactic acidosis and liver problems, are rare but require immediate medical attention. Always inform your doctor about any new or worsening symptoms while taking this medication.
Does Tenofovir alafenamide have any safety warnings?
Yes, Tenofovir alafenamide has safety warnings. It can cause lactic acidosis, which is a buildup of lactic acid in the blood, and severe liver problems. Symptoms include nausea, vomiting, stomach pain, and difficulty breathing. If you experience these, seek emergency help. Regular monitoring of kidney function is also important, as the medication can affect kidney health. Always follow your doctor's advice and report any new symptoms.
Is it safe to drink alcohol while taking Tenofovir alafenamide?
It's best to limit alcohol while taking Tenofovir alafenamide. Alcohol can affect liver function, and this medication can also impact the liver. Drinking alcohol may increase the risk of liver problems. If you choose to drink, do so in moderation and discuss with your doctor to get personalized advice based on your health situation.
Is it safe to exercise while taking Tenofovir alafenamide?
Yes, you can exercise while taking Tenofovir alafenamide. Exercise is generally safe and beneficial for your health. However, if you experience unusual fatigue or dizziness, slow down or stop exercising and rest. Always listen to your body and consult your doctor if you have concerns about your specific situation.
Is it safe to stop Tenofovir alafenamide?
Stopping Tenofovir alafenamide suddenly can cause your viral load to increase, which may worsen your condition. It's important to follow your doctor's advice when considering stopping the medication. Your doctor might suggest a gradual reduction or switching to another medication to keep your condition under control. Always consult your doctor before making any changes to your medication.
Is Tenofovir alafenamide addictive?
Tenofovir alafenamide is not addictive or habit-forming. It doesn't cause dependency or withdrawal symptoms when you stop taking it. This medication works by affecting the virus in your body, not your brain chemistry, so it doesn't lead to addiction. You won't experience cravings for this medication or feel compelled to take more than prescribed.
Is Tenofovir alafenamide safe for the elderly?
Tenofovir alafenamide is generally safe for the elderly, but they may be more vulnerable to side effects like kidney problems. Regular monitoring of kidney function is important. The elderly should be cautious and follow their doctor's advice closely to ensure safe and effective use of the medication.
What are the most common side effects of Tenofovir alafenamide?
Side effects are unwanted reactions to a medication. Common side effects of Tenofovir alafenamide include nausea, headache, and fatigue. These occur in a small percentage of people and are usually mild. If you notice new symptoms after starting the medication, they might be temporary or unrelated. Talk with your doctor before stopping any medication.
Who should avoid taking Tenofovir alafenamide?
Do not take Tenofovir alafenamide if you're allergic to it or its ingredients. Serious allergic reactions require immediate medical help. This medication is not recommended for people with severe kidney problems, as it may worsen kidney function. Always consult your doctor about any concerns or conditions that might affect your use of this medication.
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