Telotristat Ethyl
Malignant Carcinoid Syndrome, Diarrhea
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Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
NA
Controlled Drug Substance
No
telotristat ethyl
Summary
Telotristat Ethyl is used to treat carcinoid syndrome diarrhea, which is a condition caused by certain types of tumors. This medication helps reduce the frequency of bowel movements by decreasing serotonin production, which is a chemical that can cause diarrhea.
Telotristat Ethyl works by inhibiting tryptophan hydroxylase, which is an enzyme involved in the production of serotonin. Serotonin, which is a chemical in the body, can cause diarrhea when produced in excess. By reducing serotonin production, Telotristat Ethyl helps control diarrhea associated with carcinoid syndrome.
The usual starting dose of Telotristat Ethyl for adults is 250 mg three times a day with meals. Your doctor may adjust your dose based on your response and any side effects. The maximum recommended dose is 750 mg per day. Always follow your doctor's specific dosing instructions for your personal health needs.
Common side effects of Telotristat Ethyl include nausea, headache, and fatigue. These effects vary from person to person. Severe constipation is a significant side effect that requires immediate medical attention. Always inform your doctor about any new or worsening symptoms while taking Telotristat Ethyl.
Telotristat Ethyl can cause serious side effects like severe constipation, which may lead to complications. If you experience severe abdominal pain, nausea, or vomiting, contact your doctor immediately. This medication isn't for people with severe liver problems, as it may worsen liver function. Always consult your doctor about these concerns.
Indications and Purpose
How does Telotristat Ethyl work?
Telotristat Ethyl works by inhibiting tryptophan hydroxylase, which is an enzyme involved in the production of serotonin. Serotonin, which is a chemical in the body, can cause diarrhea when produced in excess. By reducing serotonin production, Telotristat Ethyl helps control diarrhea associated with carcinoid syndrome. This medication is effective in managing symptoms and improving the quality of life for patients with this condition.
Is Telotristat Ethyl effective?
Telotristat Ethyl is effective in treating carcinoid syndrome diarrhea, which is a condition caused by certain types of tumors. Clinical studies show that it significantly reduces the frequency of bowel movements in patients with this condition. This medication works by reducing the production of serotonin, which helps control diarrhea. The effectiveness of Telotristat Ethyl is supported by evidence from clinical trials, showing improved health outcomes for patients using this medication.
What is Telotristat Ethyl?
Telotristat Ethyl is a medication used to treat carcinoid syndrome diarrhea, which is a condition caused by certain types of tumors. It belongs to a class of drugs called tryptophan hydroxylase inhibitors. This medication works by reducing the production of serotonin, which helps control diarrhea. Telotristat Ethyl is used as a complementary addition to other therapies for managing carcinoid syndrome symptoms.
Directions for Use
For how long do I take Telotristat Ethyl?
Telotristat Ethyl is usually a long-term medication for managing carcinoid syndrome diarrhea, which is a condition caused by certain types of tumors. You'll typically take Telotristat Ethyl every day as a lifelong treatment unless your doctor suggests otherwise. How long you'll need this medication depends on your body's response, any side effects you experience, and changes in your overall health. Always talk with your doctor before changing or stopping your Telotristat Ethyl treatment.
How do I dispose of Telotristat Ethyl?
If you can, bring unused Telotristat Ethyl to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of this medicine properly so it doesn't harm people or the environment. If you can't find a take-back program, you can throw most medicines in the trash at home. But first, take them out of their original containers, mix them with something undesirable like used coffee grounds, seal the mixture in a plastic bag, and throw it away.
How do I take Telotristat Ethyl?
Take Telotristat Ethyl as prescribed by your doctor. It's usually taken three times a day with meals. Do not crush or chew the tablets. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Avoid taking two doses at once. Always follow your doctor's specific instructions regarding food and beverage restrictions.
How long does it take for Telotristat Ethyl to start working?
Telotristat Ethyl begins working in your body shortly after you take it, but you may not notice all the benefits right away. For carcinoid syndrome diarrhea, you might see some improvement in symptoms within a few days, but more significant changes typically take several weeks. How quickly the medication works can depend on your overall health and how your body responds. Take it exactly as prescribed for the best results.
How should I store Telotristat Ethyl?
Store Telotristat Ethyl at room temperature, away from moisture and light. Keep the medication in its original container, tightly closed, to protect it from damage. Don't store your medicine in humid places like bathrooms, where moisture in the air could affect how well the medication works. Always store Telotristat Ethyl out of children's reach to prevent accidental swallowing. Check the expiration date regularly and properly dispose of any unused or expired medication.
What is the usual dose of Telotristat Ethyl?
The usual starting dose of Telotristat Ethyl for adults is 250 mg three times a day with meals. Your doctor may adjust your dose based on your response and any side effects. The maximum recommended dose is 750 mg per day. Always follow your doctor's specific dosing instructions for your personal health needs. Dose adjustments may be necessary for special populations such as the elderly.
Warnings and Precautions
Can I take Telotristat Ethyl with other prescription drugs?
Telotristat Ethyl may interact with other medications, increasing the risk of adverse effects or reducing its effectiveness. It's important to inform your doctor about all the medicines you're taking, including prescription, over-the-counter, and herbal supplements. Your doctor can help identify any potential interactions and adjust your treatment plan accordingly. Always follow your doctor's instructions and report any unusual symptoms while taking Telotristat Ethyl.
Can Telotristat Ethyl be taken safely while breastfeeding?
The safety of Telotristat Ethyl while breastfeeding is not well-established. It's unclear if this medication passes into human breast milk. If you're taking Telotristat Ethyl and want to breastfeed, talk with your doctor about safer medication options that would allow you to nurse your baby safely. Always consult your doctor before starting or continuing Telotristat Ethyl while breastfeeding.
Can Telotristat Ethyl be taken safely while pregnant?
The safety of Telotristat Ethyl during pregnancy is not well-established. There is limited information on its use in pregnant women. If you're pregnant or planning to become pregnant, talk with your doctor about the safest way to manage your condition. Your doctor can help create a treatment plan that protects both you and your baby. Always consult your doctor before starting or continuing Telotristat Ethyl during pregnancy.
Does Telotristat Ethyl have adverse effects?
Adverse effects are unwanted reactions to a medication. With Telotristat Ethyl, common adverse effects include nausea, headache, and fatigue. These effects vary from person to person. Severe constipation is a significant side effect that requires immediate medical attention. Always inform your doctor about any new or worsening symptoms while taking Telotristat Ethyl. Your doctor can help determine if these symptoms are related to the medication.
Does Telotristat Ethyl have any safety warnings?
Yes, Telotristat Ethyl has important safety warnings. It can cause serious side effects like severe constipation, which may lead to complications. If you experience severe abdominal pain, nausea, or vomiting, contact your doctor immediately. Not adhering to these warnings can lead to serious health issues. Always follow your doctor's instructions and report any unusual symptoms while taking this medication.
Is it safe to drink alcohol while taking Telotristat Ethyl?
It's best to avoid alcohol while taking Telotristat Ethyl. Alcohol can worsen side effects like nausea and diarrhea. If you do choose to drink occasionally, limit how much alcohol you consume and watch for any worsening symptoms. Talk with your doctor about alcohol use while taking Telotristat Ethyl to get personalized advice based on your specific health situation.
Is it safe to exercise while taking Telotristat Ethyl?
You can exercise while taking Telotristat Ethyl, but keep a few things in mind. This medication can cause gastrointestinal side effects like diarrhea, which might make you feel uncomfortable during exercise. To exercise safely, stay hydrated and listen to your body. If you notice any unusual symptoms, slow down or stop exercising and rest. Most people can maintain their regular exercise routine while taking Telotristat Ethyl, but check with your doctor if you have concerns.
Is it safe to stop Telotristat Ethyl?
Stopping Telotristat Ethyl suddenly can cause your symptoms to return or worsen. It's important to talk with your doctor before stopping this medication. Your doctor might suggest gradually reducing your dose or switching to a different medication to keep your condition under control. Your doctor will help you make any medication changes safely to protect your health.
Is Telotristat Ethyl addictive?
Telotristat Ethyl is not addictive or habit-forming. This medication doesn't cause dependency or withdrawal symptoms when you stop taking it. It works by affecting the production of serotonin in the body, which doesn't lead to addiction. You won't experience cravings for this medication or feel compelled to take more than prescribed. If you have concerns about medication dependence, you can feel confident that Telotristat Ethyl doesn't carry this risk.
Is Telotristat Ethyl safe for the elderly?
Elderly patients may be more vulnerable to the side effects of Telotristat Ethyl, such as constipation and fatigue. It's important for older adults to be closely monitored by their doctor while taking this medication. Your doctor may adjust the dose based on your response and any side effects. Always follow your doctor's instructions and report any unusual symptoms while taking Telotristat Ethyl.
What are the most common side effects of Telotristat Ethyl?
Side effects are unwanted reactions that can happen when taking a medication. Common side effects of Telotristat Ethyl include nausea, headache, and fatigue. These effects vary from person to person. If you notice new symptoms after starting Telotristat Ethyl, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication. Your doctor can help determine if the symptoms are related to Telotristat Ethyl.
Who should avoid taking Telotristat Ethyl?
Don't take Telotristat Ethyl if you're allergic to it or its ingredients. Serious allergic reactions, which cause rash, hives, or swelling that makes breathing difficult, require immediate medical help. This medication isn't for people with severe liver problems, as it may worsen liver function. Always consult your doctor about these concerns and inform them of any other health conditions you have before starting Telotristat Ethyl.
