Tasimelteon
Circadian Rhythm Sleep Disorders
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Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Melatonin Receptor Agonist
Controlled Drug Substance
No
tasimelteon
Summary
Tasimelteon is used to treat non-24-hour sleep-wake disorder, which is a condition that disrupts the normal sleep-wake cycle, primarily affecting people who are blind.
Tasimelteon works by acting on melatonin receptors, which are parts of the brain that help regulate the sleep-wake cycle, improving sleep patterns and increasing nighttime sleep duration.
The usual dose of Tasimelteon for adults is 20 mg taken once daily at bedtime, without food, to ensure proper absorption.
Common side effects of Tasimelteon include drowsiness, which means feeling unusually sleepy, and headaches, which are pains in the head.
Avoid alcohol while taking Tasimelteon, as it can increase drowsiness. Do not take it if allergic to its ingredients. Use with caution if you have liver problems, which affect how the medication is processed.
Indications and Purpose
How does Tasimelteon work?
Tasimelteon works by acting on melatonin receptors in the brain, which helps regulate the sleep-wake cycle. Think of it like setting a clock to help your body know when to sleep and wake up. This action helps improve sleep patterns and increase nighttime sleep duration, especially in people with non-24-hour sleep-wake disorder.
Is Tasimelteon effective?
Tasimelteon is effective for treating non-24-hour sleep-wake disorder, which affects people who are blind. It helps regulate the sleep-wake cycle by acting on melatonin receptors in the brain. Clinical studies show Tasimelteon improves sleep patterns and increases nighttime sleep duration in affected individuals.
What is Tasimelteon?
Tasimelteon is a medication used to treat non-24-hour sleep-wake disorder, primarily in people who are blind. It belongs to a class of drugs called melatonin receptor agonists, which help regulate the sleep-wake cycle by acting on melatonin receptors in the brain. This helps improve sleep patterns and increase nighttime sleep duration.
Directions for Use
For how long do I take Tasimelteon?
Tasimelteon is usually taken long-term for managing non-24-hour sleep-wake disorder. You'll typically take it every day as a lifelong treatment unless your doctor suggests otherwise. How long you'll need this medication depends on your body's response and any side effects you experience. Always talk with your doctor before changing or stopping your Tasimelteon treatment.
How do I dispose of Tasimelteon?
Bring unused Tasimelteon to a drug take-back program or collection site at a pharmacy or hospital. If you can't find a take-back program, you can throw it in the trash at home. First, mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away.
How do I take Tasimelteon?
Take Tasimelteon once daily, at the same time each night, before bedtime. It should be taken without food to ensure proper absorption. Do not crush or chew the capsules. If you miss a dose, skip it and take the next dose at the regular time. Do not take two doses at once. Avoid alcohol while taking Tasimelteon, as it can interfere with the medication's effectiveness.
How long does it take for Tasimelteon to start working?
Tasimelteon may take several weeks to achieve its full therapeutic effect. Some people may notice improvements in sleep patterns within a few days, but it can vary. Factors like individual response and adherence to the medication schedule can affect how quickly it works. Take it exactly as prescribed for the best results.
How should I store Tasimelteon?
Store Tasimelteon at room temperature, away from moisture and light. Keep it in its original container, tightly closed, and out of reach of children. Do not store it in the bathroom, where humidity can affect the medication. Check the expiration date regularly and dispose of any unused or expired medication properly.
What is the usual dose of Tasimelteon?
The usual starting dose of Tasimelteon for adults is 20 mg taken once daily at bedtime. It should be taken without food. There are no specific dose adjustments for special populations like children or the elderly, but always follow your doctor's specific dosing instructions for your personal health needs.
Warnings and Precautions
Can I take Tasimelteon with other prescription drugs?
Tasimelteon may interact with certain medications, such as strong CYP1A2 inhibitors, which can increase its levels in the body. This may lead to increased side effects. Always inform your doctor about all the medications you are taking to avoid potential interactions and ensure safe use of Tasimelteon.
Can Tasimelteon be taken safely while breastfeeding?
There is limited information on the safety of Tasimelteon while breastfeeding. It's unclear if the medication passes into breast milk. If you're breastfeeding, talk with your doctor about the risks and benefits of using Tasimelteon. They can help you decide the best course of action for you and your baby.
Can Tasimelteon be taken safely while pregnant?
There is limited evidence on the safety of Tasimelteon during pregnancy. It's best to avoid using it unless absolutely necessary. If you're pregnant or planning to become pregnant, talk with your doctor about the safest way to manage your sleep disorder during this time.
Does Tasimelteon have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Tasimelteon include drowsiness and headache. These effects are generally mild. Serious side effects are rare but can include abnormal dreams or sleepwalking. If you experience any new or worsening symptoms, contact your doctor for advice.
Does Tasimelteon have any safety warnings?
Tasimelteon has important safety warnings. It may cause drowsiness, which can affect your ability to perform tasks that require full alertness, like driving. Avoid alcohol, as it can increase drowsiness. Not adhering to these warnings can lead to accidents or injuries. Always follow your doctor's advice and report any unusual symptoms.
Is it safe to drink alcohol while taking Tasimelteon?
It's best to avoid alcohol while taking Tasimelteon. Alcohol can increase drowsiness and interfere with the medication's effectiveness. If you choose to drink occasionally, limit your alcohol intake and be aware of increased drowsiness. Talk with your doctor about alcohol use while taking Tasimelteon.
Is it safe to exercise while taking Tasimelteon?
You can exercise while taking Tasimelteon, but be aware that it may cause drowsiness. This might affect your coordination and increase the risk of injury during physical activity. To exercise safely, avoid strenuous activities if you feel drowsy and ensure you're fully alert before engaging in exercise.
Is it safe to stop Tasimelteon?
Tasimelteon is usually taken long-term for sleep disorders. Stopping it suddenly may cause your sleep problems to return. There are no known withdrawal symptoms, but always talk with your doctor before stopping Tasimelteon. They can help you safely adjust your treatment plan if needed.
Is Tasimelteon addictive?
Tasimelteon is not considered addictive or habit-forming. It doesn't cause dependency or withdrawal symptoms when you stop taking it. If you have concerns about medication dependence, you can feel confident that Tasimelteon doesn't carry this risk while managing your sleep condition.
Is Tasimelteon safe for the elderly?
The elderly are more vulnerable to medication side effects due to age-related changes in the body. Tasimelteon is generally safe for elderly users, but they may experience increased drowsiness. It's important for elderly patients to be monitored closely by their doctor while taking Tasimelteon.
What are the most common side effects of Tasimelteon?
Side effects are unwanted reactions that can happen when taking a medication. Common side effects of Tasimelteon include drowsiness and headache. These effects are generally mild and may improve as your body adjusts to the medication. If you notice new symptoms, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking Tasimelteon?
Do not take Tasimelteon if you're allergic to it or its ingredients. Serious allergic reactions require immediate medical help. Tasimelteon should be used with caution in people with liver problems, as it may affect how the medication is processed. Always consult your doctor about these concerns.
