Sulindac
Gouty Arthritis, Rheumatoid Arthritis ... show more
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
Possible
Pharmaceutical Class
Nonsteroidal Anti-inflammatory Drug
Controlled Drug Substance
No
Sulindac
Summary
Sulindac is used to treat pain and inflammation, which is swelling and redness, associated with conditions like arthritis, which is joint inflammation, and other inflammatory disorders.
Sulindac works by inhibiting enzymes called COX-1 and COX-2, which are involved in producing substances that cause inflammation and pain. This helps reduce swelling and relieve pain.
The usual starting dose of Sulindac for adults is 150 mg to 200 mg taken twice daily. It is taken orally, which means by mouth, and should be taken with food to reduce stomach upset.
Common side effects of Sulindac include stomach upset, which is discomfort in the stomach, nausea, which is feeling sick, and dizziness, which is feeling lightheaded.
Sulindac can increase the risk of serious cardiovascular events, which are heart-related problems, and stomach bleeding. It should not be taken by people allergic to NSAIDs, which are nonsteroidal anti-inflammatory drugs.
Indications and Purpose
How does Sulindac work?
Sulindac works by inhibiting enzymes called COX-1 and COX-2, which are involved in producing substances that cause inflammation and pain. Think of it like turning down the volume on a loudspeaker. By reducing these substances, Sulindac helps relieve pain and inflammation in conditions like arthritis. This makes it effective for managing symptoms of inflammatory disorders.
Is Sulindac effective?
Sulindac is effective for treating pain and inflammation associated with conditions like arthritis. It works by reducing substances in the body that cause inflammation. Clinical studies support its effectiveness in relieving symptoms of arthritis and other inflammatory conditions. Always follow your doctor's instructions to achieve the best results.
What is Sulindac?
Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation. It works by reducing substances in the body that cause inflammation. Sulindac is commonly used for conditions like arthritis, which is joint inflammation, and other inflammatory disorders. It can be used alone or with other therapies to manage symptoms.
Directions for Use
For how long do I take Sulindac?
Sulindac is usually taken for short-term relief of pain and inflammation. The duration depends on your condition and doctor's advice. For chronic conditions, your doctor may recommend longer use. Always follow your doctor's instructions and discuss any concerns about the length of treatment with them.
How do I dispose of Sulindac?
Dispose of unused Sulindac by taking it to a drug take-back program or collection site at a pharmacy or hospital. If no take-back program is available, mix the medication with an undesirable substance like used coffee grounds, seal it in a plastic bag, and throw it away in the trash. This helps prevent harm to people and the environment.
How do I take Sulindac?
Take Sulindac as prescribed by your doctor, usually twice daily. It's best to take it with food to reduce stomach upset. Swallow the tablet whole; do not crush or chew it. If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not double up on doses. Avoid alcohol while taking Sulindac, as it can increase the risk of stomach bleeding.
How long does it take for Sulindac to start working?
Sulindac starts working within a few hours to relieve pain and inflammation. However, the full therapeutic effect may take several days to become noticeable. Factors like your condition, age, and overall health can affect how quickly you experience relief. Take Sulindac exactly as prescribed for the best results.
How should I store Sulindac?
Store Sulindac at room temperature, away from moisture and light. Keep it in a tightly closed container. Do not store it in the bathroom, where humidity can affect the medication. Keep it out of reach of children and pets. Check the expiration date regularly and dispose of any unused or expired medication properly.
What is the usual dose of Sulindac?
The usual starting dose of Sulindac for adults is 150 mg to 200 mg twice daily. Your doctor may adjust the dose based on your response and any side effects. The maximum recommended dose is 400 mg per day. For elderly patients or those with kidney issues, dose adjustments may be necessary. Always follow your doctor's specific dosing instructions for your health needs.
Warnings and Precautions
Can I take Sulindac with other prescription drugs?
Sulindac can interact with other medications, increasing the risk of side effects. Major interactions include blood thinners like warfarin, which can increase bleeding risk. Combining Sulindac with other NSAIDs or corticosteroids can increase the risk of stomach ulcers. Always inform your doctor about all medications you take to manage potential interactions.
Can Sulindac be taken safely while breastfeeding?
Sulindac is generally not recommended while breastfeeding. Limited data is available on its excretion into breast milk and potential effects on the infant. If you need to take Sulindac while breastfeeding, consult your doctor. They can help assess the risks and benefits and suggest safer alternatives if necessary.
Can Sulindac be taken safely while pregnant?
Sulindac is not recommended during pregnancy, especially in the third trimester. It may harm the unborn baby or cause complications during delivery. Limited human data is available, but animal studies suggest potential risks. If you're pregnant or planning to become pregnant, talk with your doctor about safer alternatives for managing pain and inflammation.
Does Sulindac have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Sulindac include stomach upset, nausea, and dizziness. Serious effects like heart attack, stroke, or stomach bleeding are rare but require immediate medical attention. If you notice any new or worsening symptoms, contact your doctor. They can help determine if these are related to Sulindac and advise on the best course of action.
Does Sulindac have any safety warnings?
Yes, Sulindac has important safety warnings. It can increase the risk of serious cardiovascular events like heart attack or stroke, especially with long-term use. It may also cause stomach bleeding or ulcers. If you experience chest pain, weakness, or bloody stools, seek medical help immediately. Always follow your doctor's advice and report any unusual symptoms while taking Sulindac.
Is it safe to drink alcohol while taking Sulindac?
It's best to avoid alcohol while taking Sulindac. Alcohol can increase the risk of stomach bleeding and ulcers, which are potential side effects of Sulindac. If you choose to drink, limit your alcohol intake and watch for symptoms like stomach pain or bloody stools. Talk with your doctor about alcohol use while taking Sulindac for personalized advice.
Is it safe to exercise while taking Sulindac?
Yes, you can exercise while taking Sulindac, but be cautious. Sulindac can cause dizziness or stomach upset, which might affect your ability to exercise. If you feel dizzy or unwell during physical activity, stop and rest. Drink plenty of water to stay hydrated. Consult your doctor if you have concerns about exercising while on Sulindac.
Is it safe to stop Sulindac?
Sulindac is often used for short-term relief of pain and inflammation. Stopping it suddenly is generally safe, but your symptoms may return. If you have been taking it for a long time, consult your doctor before stopping. They can advise on the best way to discontinue use and manage your condition safely.
Is Sulindac addictive?
Sulindac is not addictive or habit-forming. It does not cause dependency or withdrawal symptoms when you stop taking it. Sulindac works by reducing inflammation and pain, and it does not affect brain chemistry in ways that could lead to addiction. If you have concerns about medication dependence, you can feel confident that Sulindac doesn't carry this risk.
Is Sulindac safe for the elderly?
Elderly individuals are more vulnerable to the side effects of Sulindac, such as stomach bleeding and kidney problems. It's important for older adults to use Sulindac under close medical supervision. Doctors may prescribe a lower dose and monitor for any adverse effects. Always discuss your health conditions with your doctor before starting Sulindac.
What are the most common side effects of Sulindac?
Side effects are unwanted reactions to a medication. Common side effects of Sulindac include stomach upset, nausea, and dizziness. These effects vary from person to person. If you notice new symptoms after starting Sulindac, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking Sulindac?
Do not take Sulindac if you're allergic to it or other NSAIDs, which are nonsteroidal anti-inflammatory drugs. It is contraindicated in people with a history of asthma attacks or severe allergic reactions to aspirin. Avoid Sulindac if you have active stomach ulcers or severe kidney disease. Always consult your doctor about your medical history before starting Sulindac.
