Sucroferric Oxyhydroxide
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
NA
Controlled Drug Substance
No
Summary
Sucroferric oxyhydroxide is used to manage high phosphate levels in people with chronic kidney disease, which is a condition where the kidneys can't filter waste effectively. High phosphate levels can lead to bone and heart problems, so controlling them is important for overall health.
Sucroferric oxyhydroxide works by binding to phosphate in the digestive tract, which prevents its absorption into the bloodstream. This helps maintain a healthy balance of phosphate in the body, reducing the risk of complications like bone and heart problems.
The usual starting dose of sucroferric oxyhydroxide for adults is 500 mg, taken three times a day with meals. The tablets should be swallowed whole, not crushed or chewed. Your doctor may adjust the dose based on your phosphate levels and response to the medication.
Common side effects of sucroferric oxyhydroxide include diarrhea, nausea, and dark-colored stools, which are generally mild and occur in a small percentage of people. If you experience severe or persistent symptoms, contact your doctor immediately.
Sucroferric oxyhydroxide can interfere with the absorption of other oral medications, so take other medicines at least one hour before or two hours after. Absolute contraindications include allergy to the medication or its ingredients. Seek medical attention for any unusual symptoms or allergic reactions.
Indications and Purpose
How does sucroferric oxyhydroxide work?
Sucroferric oxyhydroxide works by binding to phosphate in the digestive tract, preventing its absorption into the bloodstream. Think of it like a sponge soaking up excess phosphate, which helps maintain a healthy balance in the body. This process is important for people with chronic kidney disease, as it helps prevent complications associated with high phosphate levels, such as bone and heart problems. By reducing phosphate absorption, sucroferric oxyhydroxide helps manage phosphate levels effectively.
Is sucroferric oxyhydroxide effective?
Yes, sucroferric oxyhydroxide is effective in managing high phosphate levels in people with chronic kidney disease. It works by binding to phosphate in the digestive tract, preventing its absorption into the bloodstream. Clinical studies show that it effectively lowers phosphate levels, helping to maintain balance and prevent complications associated with high phosphate. Always follow your doctor's instructions to achieve the best results.
What is sucroferric oxyhydroxide?
Sucroferric oxyhydroxide is a phosphate binder used to manage high phosphate levels in people with chronic kidney disease. It works by binding to phosphate in the digestive tract, preventing its absorption into the bloodstream. This helps maintain a healthy balance of phosphate in the body, which is important for bone health and preventing complications associated with high phosphate levels. Sucroferric oxyhydroxide is usually taken with meals and is part of a comprehensive treatment plan that may include diet and other medications.
Directions for Use
For how long do I take sucroferric oxyhydroxide?
Sucroferric oxyhydroxide is usually a long-term medication for managing high phosphate levels in people with chronic kidney disease. You'll typically take it every day as part of your ongoing treatment unless your doctor suggests otherwise. Stopping this medication without medical advice could cause your phosphate levels to rise. How long you'll need this medication depends on your body's response, any side effects you experience, and changes in your overall health. Always talk with your doctor before changing or stopping your treatment.
How do I dispose of sucroferric oxyhydroxide?
To dispose of sucroferric oxyhydroxide, take it to a drug take-back program or collection site at a pharmacy or hospital. If you can't find a take-back program, you can throw it in the trash at home. First, remove it from its original container, mix it with something undesirable like used coffee grounds, seal the mixture in a plastic bag, and throw it away. This helps prevent accidental ingestion by children or pets.
How do I take sucroferric oxyhydroxide?
Take sucroferric oxyhydroxide as directed by your doctor, usually with meals. This medicine is typically taken three times a day. Do not crush or chew the tablets; swallow them whole. If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not take two doses at once. Always follow your doctor's specific instructions regarding diet and fluid intake while taking this medication.
How long does it take for sucroferric oxyhydroxide to start working?
Sucroferric oxyhydroxide begins working shortly after you take it, as it binds to phosphate in the digestive tract. However, you may not notice all the benefits right away. It may take several weeks for your blood tests to show significant changes in phosphate levels. How quickly the medication works can depend on your overall health and how well you follow your treatment plan. Regular check-ups with your doctor are important to monitor your progress.
How should I store sucroferric oxyhydroxide?
Store sucroferric oxyhydroxide at room temperature, away from moisture and light. Keep it in a tightly closed container to protect it from damage. Avoid storing it in humid places like bathrooms, where moisture in the air could affect its effectiveness. Always store it out of children's reach to prevent accidental ingestion. Check the expiration date regularly and properly dispose of any unused or expired medication.
What is the usual dose of sucroferric oxyhydroxide?
The usual starting dose of sucroferric oxyhydroxide for adults is 500 mg, taken three times a day with meals. Your doctor may adjust the dose based on your phosphate levels and how you respond to the medication. The maximum recommended dose is 3,000 mg per day. Always follow your doctor's specific dosing instructions for your health needs. Dose adjustments may be necessary for special populations, such as the elderly.
Warnings and Precautions
Can I take sucroferric oxyhydroxide with other prescription drugs?
Sucroferric oxyhydroxide can interact with other oral medications by affecting their absorption. This is particularly concerning for medications that need precise blood levels to work effectively. To avoid interactions, take other medications at least one hour before or two hours after sucroferric oxyhydroxide. Always inform your doctor about all the medications you are taking to ensure safe and effective treatment.
Can sucroferric oxyhydroxide be taken safely while breastfeeding?
The safety of sucroferric oxyhydroxide while breastfeeding is not well-established. It's unclear if this medication passes into breast milk or affects milk supply. If you're breastfeeding or planning to breastfeed, talk with your doctor about the safest options for managing your condition. Your doctor can help determine if sucroferric oxyhydroxide is appropriate for you or suggest alternative treatments.
Can sucroferric oxyhydroxide be taken safely while pregnant?
The safety of sucroferric oxyhydroxide during pregnancy is not well-established. Limited evidence is available, and its use should be considered only if the benefits outweigh the risks. If you are pregnant or planning to become pregnant, talk with your doctor about the safest way to manage your condition. Your doctor can help create a treatment plan that protects both you and your baby.
Does sucroferric oxyhydroxide have adverse effects?
Adverse effects are unwanted reactions that can occur with medication use. With sucroferric oxyhydroxide, common adverse effects include diarrhea, nausea, and dark-colored stools. These effects are generally mild and occur in a small percentage of users. Serious adverse effects are rare but can include allergic reactions, such as rash or difficulty breathing. If you experience any severe or persistent symptoms, contact your doctor immediately. Always inform your healthcare provider about any new or worsening symptoms while taking this medication.
Does sucroferric oxyhydroxide have any safety warnings?
Yes, sucroferric oxyhydroxide has safety warnings. It can interfere with the absorption of other oral medications, so take other medicines at least one hour before or two hours after. Not adhering to this can reduce the effectiveness of your other medications. If you experience any unusual symptoms or allergic reactions, such as rash or difficulty breathing, seek medical attention immediately. Always follow your doctor's instructions and inform them of all medications you are taking.
Is it safe to drink alcohol while taking sucroferric oxyhydroxide?
It's best to avoid alcohol while taking sucroferric oxyhydroxide. Alcohol can irritate the stomach and may worsen side effects like nausea or diarrhea. If you choose to drink occasionally, limit your alcohol intake and watch for any symptoms that may arise. Talk with your doctor about alcohol use while taking this medication to get personalized advice based on your health situation.
Is it safe to exercise while taking sucroferric oxyhydroxide?
Yes, it's generally safe to exercise while taking sucroferric oxyhydroxide. This medication doesn't typically limit exercise capacity. However, if you experience side effects like nausea or diarrhea, you might feel uncomfortable during physical activity. To exercise safely, stay hydrated and listen to your body. If you notice any unusual symptoms during exercise, slow down or stop and rest. Consult your doctor if you have concerns about your specific situation.
Is it safe to stop sucroferric oxyhydroxide?
It's important to talk with your doctor before stopping sucroferric oxyhydroxide. This medication is usually used long-term to manage high phosphate levels in people with chronic kidney disease. Stopping it suddenly can lead to increased phosphate levels, which can cause health problems. Your doctor can guide you on how to safely stop or adjust your medication if needed.
Is sucroferric oxyhydroxide addictive?
No, sucroferric oxyhydroxide is not addictive or habit-forming. This medication does not cause dependency or withdrawal symptoms when you stop taking it. It works by binding to phosphate in the digestive tract to prevent its absorption, which doesn't affect brain chemistry in ways that could lead to addiction. You won't experience cravings for this medication or feel compelled to take more than prescribed. If you have concerns about medication dependence, you can feel confident that sucroferric oxyhydroxide doesn't carry this risk.
Is sucroferric oxyhydroxide safe for the elderly?
Sucroferric oxyhydroxide is generally safe for elderly patients, but they may be more vulnerable to side effects. The elderly often have multiple health conditions and take several medications, increasing the risk of interactions and side effects. Common side effects like diarrhea or nausea may be more pronounced in older adults. Regular monitoring and communication with a healthcare provider are important to ensure safe and effective use of this medication in the elderly.
What are the most common side effects of sucroferric oxyhydroxide?
Side effects are unwanted reactions that can happen when taking a medication. Common side effects of sucroferric oxyhydroxide include diarrhea, nausea, and dark-colored stools. These effects are generally mild and occur in a small percentage of people. If you notice new symptoms after starting sucroferric oxyhydroxide, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking sucroferric oxyhydroxide?
Absolute contraindications for sucroferric oxyhydroxide include allergy to the medication or its ingredients. Relative contraindications include conditions where the benefits must outweigh the risks, such as severe gastrointestinal disorders. Always inform your doctor about your medical history and any allergies before starting this medication. Your doctor will determine if sucroferric oxyhydroxide is safe for you.
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