Sucralfate

Duodenal Ulcer, Esophagitis ... show more

Drug Status

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Government Approvals

US(FDA), UK(BNF)

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WHO Essential Medicine

NO

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Known Teratogen

No

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Pharmaceutical Class

Aluminum Complex

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Controlled Drug Substance

No

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Drug Ingredient

sucralfate

Summary

  • Sucralfate is used to treat and prevent ulcers in the stomach and intestines, which are sores that develop on the lining of these organs. It is also used to prevent ulcers in people taking certain medications that can cause stomach irritation.

  • Sucralfate works by forming a protective barrier over ulcers, which are open sores, in the stomach lining. This barrier acts like a bandage, shielding the ulcer from stomach acid and allowing it to heal.

  • The usual adult dose of Sucralfate is 1 gram taken four times a day. It is typically taken on an empty stomach, one hour before meals and at bedtime. The tablet should be swallowed whole, not crushed or chewed.

  • Common side effects of Sucralfate include constipation, which is difficulty in passing stools, dry mouth, and upset stomach. These effects are usually mild and occur in a small percentage of people.

  • Sucralfate can interfere with the absorption of other medications, so it should be taken at least two hours apart from other drugs. People with severe kidney problems should use it cautiously due to its aluminum content, which can accumulate in the body.

Indications and Purpose

How does Sucralfate work?

Sucralfate works by forming a protective barrier over ulcers in the stomach lining. This barrier acts like a bandage, shielding the ulcer from stomach acid and allowing it to heal. Sucralfate doesn't neutralize stomach acid but instead creates a physical barrier. This helps reduce pain and promotes healing. It's effective for treating and preventing ulcers in the stomach and intestines.

Is Sucralfate effective?

Yes, Sucralfate is effective for treating ulcers in the stomach and intestines. It works by forming a protective barrier over the ulcer, allowing it to heal. Clinical studies show that Sucralfate significantly improves healing rates for ulcers. It is also used to prevent ulcers in people taking certain medications. Sucralfate is generally well-tolerated and effective in promoting ulcer healing.

What is Sucralfate?

Sucralfate is a medication used to treat ulcers in the stomach and intestines. It belongs to a class of drugs called protectants. Sucralfate works by forming a protective barrier over the ulcer, allowing it to heal. It is also used to prevent ulcers in people taking certain medications. Sucralfate is usually taken short-term and is effective in promoting ulcer healing.

Directions for Use

For how long do I take Sucralfate?

Sucralfate is usually taken short-term for healing ulcers, typically for 4 to 8 weeks. Your doctor will determine the exact duration based on your condition and response to treatment. It's important to follow your doctor's instructions and not stop the medication early, even if you feel better. Stopping too soon may prevent complete healing. Always consult your doctor before making changes to your treatment plan.

How do I dispose of Sucralfate?

Dispose of Sucralfate by taking it to a drug take-back program or collection site at a pharmacy or hospital. If these options aren't available, you can throw it in the trash at home. First, remove it from its original container, mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and then throw it away. This helps prevent accidental ingestion or harm to the environment.

How do I take Sucralfate?

Take Sucralfate as directed by your doctor, usually four times a day. It's best taken on an empty stomach, one hour before meals and at bedtime. Swallow the tablet whole; do not crush or chew it. If you miss a dose, take it as soon as you remember, unless it's close to the next dose. In that case, skip the missed dose. Do not double up on doses. Avoid taking antacids within 30 minutes before or after taking Sucralfate, as they can interfere with its effectiveness.

How long does it take for Sucralfate to start working?

Sucralfate starts working within a few hours of taking it, forming a protective barrier over the ulcer. However, it may take several weeks to achieve full healing. The time it takes to notice improvement can vary based on the severity of the ulcer and individual factors. Follow your doctor's instructions and continue taking Sucralfate as prescribed for the best results.

How should I store Sucralfate?

Store Sucralfate at room temperature, away from moisture and light. Keep it in a tightly closed container to protect it from humidity, which can affect its effectiveness. Avoid storing it in the bathroom, where moisture levels are high. Always keep Sucralfate out of reach of children to prevent accidental ingestion. Check the expiration date regularly and dispose of any unused or expired medication properly.

What is the usual dose of Sucralfate?

The usual adult dose of Sucralfate is 1 gram taken four times a day. It's typically taken on an empty stomach, one hour before meals and at bedtime. Your doctor may adjust the dose based on your specific needs. For children or the elderly, dose adjustments may be necessary. Always follow your doctor's instructions regarding the dosage and duration of treatment with Sucralfate.

Warnings and Precautions

Can I take Sucralfate with other prescription drugs?

Sucralfate can interact with certain medications, reducing their effectiveness. It may bind to drugs like digoxin, warfarin, and certain antibiotics, preventing their absorption. To avoid interactions, take other medications at least two hours before or after Sucralfate. Always inform your doctor about all the medications you are taking to ensure safe and effective treatment. Your doctor can help manage any potential interactions.

Can Sucralfate be taken safely while breastfeeding?

Sucralfate is generally considered safe while breastfeeding, as it is minimally absorbed into the bloodstream. This means it is unlikely to pass into breast milk in significant amounts. However, always consult your doctor before using Sucralfate while breastfeeding. They can provide personalized advice based on your specific situation and ensure the safety of both you and your baby.

Can Sucralfate be taken safely while pregnant?

Sucralfate is generally considered safe during pregnancy, but you should consult your doctor before using it. Limited studies suggest it doesn't harm the unborn baby, but more research is needed. Your doctor will weigh the benefits and risks before recommending Sucralfate during pregnancy. Always follow your doctor's advice to ensure the safety of both you and your baby.

Does Sucralfate have adverse effects?

Adverse effects are unwanted reactions to a medication. With Sucralfate, common adverse effects include constipation, dry mouth, and upset stomach. These effects are usually mild. Serious adverse effects are rare but can include allergic reactions like rash or difficulty breathing. If you experience severe side effects, contact your doctor immediately. Always inform your healthcare provider about any new or worsening symptoms while taking Sucralfate.

Does Sucralfate have any safety warnings?

Yes, Sucralfate has safety warnings. It can interfere with the absorption of other medications, so take it at least two hours apart from other drugs. It may cause constipation, so drink plenty of fluids. If you have kidney problems, use Sucralfate with caution, as it contains aluminum, which can accumulate in the body. Not following these warnings can lead to reduced effectiveness of other medications or increased risk of side effects.

Is it safe to drink alcohol while taking Sucralfate?

It's best to avoid alcohol while taking Sucralfate. Alcohol can irritate the stomach lining and may worsen ulcer symptoms. Drinking alcohol might also interfere with the healing process. If you choose to drink, do so in moderation and monitor for any worsening symptoms. Talk with your doctor about alcohol use while taking Sucralfate to get personalized advice based on your health situation.

Is it safe to exercise while taking Sucralfate?

Yes, it's safe to exercise while taking Sucralfate. This medication doesn't typically limit exercise capacity. However, if you experience any side effects like dizziness or stomach discomfort, adjust your activity level accordingly. Stay hydrated and listen to your body. If you have concerns about exercising while on Sucralfate, consult your doctor for personalized advice.

Is it safe to stop Sucralfate?

Yes, it's generally safe to stop Sucralfate, but you should consult your doctor first. Sucralfate is often used short-term for healing ulcers. Stopping it suddenly may not cause withdrawal symptoms, but it could affect ulcer healing. Your doctor can guide you on how to stop the medication safely and discuss alternative treatments if needed.

Is Sucralfate addictive?

No, Sucralfate is not addictive or habit-forming. It does not cause dependency or withdrawal symptoms when you stop taking it. Sucralfate works by forming a protective barrier on ulcers in the stomach lining, which doesn't affect brain chemistry or lead to addiction. You can take Sucralfate as prescribed without worrying about developing a dependency on the medication.

Is Sucralfate safe for the elderly?

Sucralfate is generally safe for the elderly, but they may be more sensitive to its effects, such as constipation. Older adults with kidney problems should use it cautiously due to the aluminum content, which can accumulate in the body. Regular monitoring by a healthcare provider is recommended to ensure safety and effectiveness. Always follow your doctor's advice when using Sucralfate.

What are the most common side effects of Sucralfate?

Side effects are unwanted reactions to a medication. Common side effects of Sucralfate include constipation, dry mouth, and upset stomach. These occur in a small percentage of people and are usually mild. If you experience new symptoms after starting Sucralfate, they might be temporary or unrelated to the medication. Talk with your doctor if you have concerns about side effects or if they persist.

Who should avoid taking Sucralfate?

Sucralfate should not be used if you are allergic to it or any of its ingredients. People with severe kidney problems should use it cautiously, as it contains aluminum, which can accumulate in the body. If you have difficulty swallowing or a history of intestinal blockage, consult your doctor before using Sucralfate. Always discuss your medical history with your doctor to ensure Sucralfate is safe for you.