Sparsentan
Proteinuria
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Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Angiotensin 2 Receptor Blocker and Endothelin Receptor Antagonist
Controlled Drug Substance
No
sparsentan
Summary
Sparsentan is used to treat certain kidney conditions and high blood pressure. It helps protect the kidneys and lower blood pressure, which is the force of blood against the walls of your arteries.
Sparsentan works by blocking specific proteins called endothelin and angiotensin receptors, which can cause blood vessels to tighten. By blocking them, it helps relax blood vessels, lower blood pressure, and protect the kidneys.
Sparsentan is usually taken once daily, either with or without food. Your doctor will determine the right dose for you based on your condition and how you respond to the medication.
Common side effects of Sparsentan include dizziness and low blood pressure, which is when your blood pressure drops below the normal range. These effects can vary from person to person.
Sparsentan can cause low blood pressure and affect kidney function. It's not recommended for people with severe liver problems or during pregnancy. Always inform your doctor about all medications you're taking to avoid interactions.
Indications and Purpose
How does Sparsentan work?
Sparsentan works by blocking specific proteins in the body called endothelin and angiotensin receptors. These proteins can cause blood vessels to tighten and increase blood pressure. By blocking them, Sparsentan helps relax blood vessels, lower blood pressure, and protect the kidneys. This makes it helpful for people with certain kidney conditions and high blood pressure.
Is Sparsentan effective?
Sparsentan is effective in treating certain kidney conditions and high blood pressure. It works by blocking specific proteins in the body, which helps protect the kidneys and lower blood pressure. Clinical studies support its effectiveness in improving health outcomes for these conditions. Always follow your doctor's advice to achieve the best results.
What is Sparsentan?
Sparsentan is a medication used to treat certain kidney conditions and high blood pressure. It belongs to a class of drugs called dual endothelin angiotensin receptor antagonists, which work by blocking specific proteins in the body. This helps protect the kidneys and lower blood pressure. Sparsentan is usually used as part of a comprehensive treatment plan.
Directions for Use
For how long do I take Sparsentan?
Sparsentan is usually a long-term medication for managing ongoing health conditions like kidney disease and high blood pressure. You'll typically take Sparsentan every day as a lifelong treatment unless your doctor suggests otherwise. How long you'll need this medication depends on your body's response and any side effects you experience.
How do I dispose of Sparsentan?
Bring unused Sparsentan to a drug take-back program or collection site at a pharmacy or hospital. If you can't find a take-back program, you can throw it in the trash at home. First, take it out of its original container, mix it with something undesirable like used coffee grounds, seal the mixture in a plastic bag, and throw it away.
How do I take Sparsentan?
Take Sparsentan exactly as your doctor prescribes. It's usually taken once daily, and you can take it with or without food. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not take two doses at once. Always follow your doctor's specific advice about diet and fluid intake while taking this medication.
How long does it take for Sparsentan to start working?
Sparsentan begins working in your body shortly after you take it, but you may not notice all the benefits right away. For blood pressure, you might see improvement within a few weeks. For kidney conditions, the full benefits may take longer to appear. How quickly the medication works can depend on your overall health and specific condition.
How should I store Sparsentan?
Store Sparsentan at room temperature, away from moisture and light. Keep it in a tightly closed container. Don't store it in humid places like bathrooms. Always keep Sparsentan out of children's reach to prevent accidental swallowing. Check the expiration date regularly and properly dispose of any unused or expired medication.
What is the usual dose of Sparsentan?
The usual starting dose of Sparsentan for adults is determined by your doctor based on your specific condition. It's typically taken once daily. Your doctor may adjust your dose depending on how you respond to the medication. Always follow your doctor's specific dosing instructions for your personal health needs.
Warnings and Precautions
Can I take Sparsentan with other prescription drugs?
Sparsentan can interact with other medications that lower blood pressure, increasing the risk of low blood pressure. It may also interact with certain diuretics, which are medications that help remove excess fluid from the body. Always inform your doctor about all the medications you're taking to avoid potential interactions.
Can Sparsentan be taken safely while breastfeeding?
Sparsentan is not recommended while breastfeeding. There's limited information about whether it passes into human breast milk. If you're taking Sparsentan and want to breastfeed, talk with your doctor about safer medication options that would allow you to nurse your baby safely.
Can Sparsentan be taken safely while pregnant?
Sparsentan isn't recommended during pregnancy due to potential risks to the unborn baby. There's limited information on its safety in pregnant women. If you're pregnant or planning to become pregnant, talk with your doctor about the safest way to manage your condition during this important time.
Does Sparsentan have adverse effects?
Adverse effects are unwanted reactions to a medication. Sparsentan can cause dizziness, low blood pressure, and kidney function changes. These effects vary in frequency and severity. If you notice any new or worsening symptoms, contact your doctor. They can help determine if these symptoms are related to Sparsentan and suggest appropriate actions.
Does Sparsentan have any safety warnings?
Yes, Sparsentan has important safety warnings. It can cause low blood pressure, especially if you're dehydrated or take other medications that lower blood pressure. It may also affect kidney function. Regular monitoring by your doctor is important. If you experience symptoms like dizziness, fainting, or unusual tiredness, contact your doctor immediately. Always follow your doctor's advice and report any new symptoms.
Is it safe to drink alcohol while taking Sparsentan?
It's best to avoid alcohol while taking Sparsentan. Alcohol can increase the risk of low blood pressure and dizziness. If you do choose to drink occasionally, limit how much alcohol you consume and watch for warning signs like dizziness or fainting. Talk with your doctor about alcohol use while taking Sparsentan.
Is it safe to exercise while taking Sparsentan?
You can exercise while taking Sparsentan, but be cautious. This medication can cause low blood pressure, which might make you feel dizzy during exercise. To exercise safely, drink plenty of water and watch for signs of dizziness or unusual fatigue. If you notice these symptoms, slow down or stop exercising and rest.
Is it safe to stop Sparsentan?
Stopping Sparsentan suddenly can cause your condition to worsen. Always talk with your doctor before stopping the medication. They might suggest gradually reducing your dose or switching to a different medication to keep your condition under control. Your doctor will help you make any medication changes safely to protect your health.
Is Sparsentan addictive?
Sparsentan is not addictive or habit-forming. This medication doesn't cause dependency or withdrawal symptoms when you stop taking it. You won't experience cravings for this medication or feel compelled to take more than prescribed. If you have concerns about medication dependence, you can feel confident that Sparsentan doesn't carry this risk.
Is Sparsentan safe for the elderly?
Elderly individuals may be more vulnerable to the side effects of Sparsentan, such as low blood pressure and dizziness. Regular monitoring by a doctor is important to ensure safety. If you're elderly and taking Sparsentan, your doctor will adjust your treatment as needed to minimize risks.
What are the most common side effects of Sparsentan?
Side effects are unwanted reactions that can happen when taking a medication. Common side effects of Sparsentan include dizziness and low blood pressure. These effects vary from person to person. If you notice new symptoms after starting Sparsentan, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking Sparsentan?
Don't take Sparsentan if you're allergic to it or its ingredients. It's not recommended for people with severe liver problems. Use caution if you have low blood pressure or are taking other medications that lower blood pressure. Always consult your doctor about these concerns before starting Sparsentan.
