Selexipag
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Prostacyclin Receptor Agonist
Controlled Drug Substance
No
selexipag
Summary
Selexipag is used to treat pulmonary arterial hypertension, which is high blood pressure in the lungs. This condition makes it hard for blood to flow through the lungs, causing symptoms like shortness of breath and fatigue. Selexipag helps improve exercise capacity and slows down the progression of the disease.
Selexipag works by activating prostacyclin receptors, which are parts of cells that help relax blood vessels in the lungs. This relaxation improves blood flow and reduces pressure in the lungs, making it easier for the heart to pump blood. Think of it like opening a valve to allow more water to flow through a pipe.
The usual starting dose of Selexipag for adults is 200 micrograms taken twice daily. Your doctor may gradually increase your dose based on how you respond and tolerate the medication. The maximum recommended dose is 1600 micrograms twice daily. Always follow your doctor's specific dosing instructions for your personal health needs.
Common side effects of Selexipag include headache, diarrhea, and nausea, which are unwanted reactions to the medication. These effects can vary from person to person and are usually mild to moderate. If you experience severe or persistent side effects, it's important to talk with your doctor for further advice.
Selexipag can cause low blood pressure, which is when your blood pressure drops too low, leading to dizziness or fainting. It's not recommended for people with severe liver problems, which affect how the body processes the medication. Always inform your doctor about any allergies or conditions before starting Selexipag.
Indications and Purpose
How does Selexipag work?
Selexipag works by activating prostacyclin receptors in the blood vessels of the lungs. This action relaxes the blood vessels, improving blood flow and reducing the pressure in the lungs. Think of it like opening a valve to allow more water to flow through a pipe. This helps reduce the workload on the heart.
Is Selexipag effective?
Selexipag is effective in treating pulmonary arterial hypertension, which is high blood pressure in the lungs. It works by relaxing blood vessels in the lungs, improving blood flow, and reducing the workload on the heart. Clinical studies show Selexipag helps improve exercise capacity and delay disease progression in patients with this condition.
What is Selexipag?
Selexipag is a medication used to treat pulmonary arterial hypertension, which is high blood pressure in the lungs. It belongs to a class of drugs called prostacyclin receptor agonists, which work by relaxing blood vessels in the lungs to improve blood flow. This helps reduce the workload on the heart and improve exercise capacity.
Directions for Use
For how long do I take Selexipag?
Selexipag is usually a long-term medication for managing pulmonary arterial hypertension, which is high blood pressure in the lungs. You'll typically take Selexipag every day as a lifelong treatment unless your doctor suggests otherwise. How long you'll need this medication depends on your body's response and any side effects you experience.
How do I dispose of Selexipag?
Dispose of Selexipag by taking it to a drug take-back program or collection site at a pharmacy or hospital. If you can't find a take-back program, you can throw it in the trash at home. First, mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away.
How do I take Selexipag?
Take Selexipag as prescribed by your doctor, usually twice daily. You can take it with or without food. Do not crush or chew the tablets. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not take two doses at once. Always follow your doctor's specific instructions.
How long does it take for Selexipag to start working?
Selexipag begins working in your body shortly after you take it. However, you may not notice all the benefits right away. It may take several weeks to see significant improvements in symptoms like shortness of breath. How quickly the medication works can depend on your overall health and response to treatment.
How should I store Selexipag?
Store Selexipag at room temperature, away from moisture and light. Keep it in a tightly closed container. Don't store it in humid places like bathrooms. Always keep Selexipag out of children's reach to prevent accidental swallowing. Check the expiration date regularly and properly dispose of any unused or expired medication.
What is the usual dose of Selexipag?
The usual starting dose of Selexipag for adults is 200 micrograms twice daily. Your doctor may gradually increase your dose based on your response and tolerance. The maximum recommended dose is 1600 micrograms twice daily. Always follow your doctor's specific dosing instructions for your personal health needs.
Warnings and Precautions
Can I take Selexipag with other prescription drugs?
Selexipag can interact with certain medications, increasing the risk of side effects. For example, it may interact with blood pressure medications, leading to low blood pressure. Always inform your doctor about all the medicines you take to avoid potential interactions. Your doctor can adjust your treatment to ensure safety.
Can Selexipag be taken safely while breastfeeding?
Selexipag is not recommended while breastfeeding. There's limited information on whether it passes into human breast milk. If you're taking Selexipag and want to breastfeed, talk with your doctor about safer medication options that would allow you to nurse your baby safely.
Can Selexipag be taken safely while pregnant?
Selexipag is not recommended during pregnancy. There's limited information on its safety for pregnant women. If you're pregnant or planning to become pregnant, talk with your doctor about the safest way to manage your condition. Your doctor can help create a treatment plan that protects both you and your baby.
Does Selexipag have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Selexipag include headache, diarrhea, and nausea. These effects vary from person to person. Serious side effects like low blood pressure or jaw pain require immediate medical attention. Always tell your doctor about any new or worsening symptoms while taking Selexipag.
Does Selexipag have any safety warnings?
Selexipag has important safety warnings. It can cause low blood pressure, which is when your blood pressure drops too low, leading to dizziness or fainting. It may also cause jaw pain or muscle pain. If you experience these symptoms, contact your doctor. Always follow your doctor's advice and report any new or worsening symptoms while taking Selexipag.
Is it safe to drink alcohol while taking Selexipag?
It's best to avoid alcohol while taking Selexipag. Alcohol can lower blood pressure, which may worsen side effects like dizziness or fainting. If you choose to drink occasionally, limit your alcohol intake and watch for warning signs like dizziness or lightheadedness. Talk with your doctor about alcohol use while taking Selexipag.
Is it safe to exercise while taking Selexipag?
You can exercise while taking Selexipag, but be cautious. This medication can cause low blood pressure, which might make you feel dizzy during exercise. To exercise safely, drink plenty of water and watch for signs of dizziness or fatigue. If you notice these symptoms, slow down or stop exercising and rest.
Is it safe to stop Selexipag?
Stopping Selexipag suddenly can cause your condition to worsen. If you're taking it for pulmonary arterial hypertension, stopping could lead to increased symptoms. Always talk with your doctor before stopping Selexipag. They might suggest gradually reducing your dose or switching to a different medication to keep your condition under control.
Is Selexipag addictive?
Selexipag is not addictive or habit-forming. This medication doesn't cause dependency or withdrawal symptoms when you stop taking it. Selexipag works by affecting blood vessels to help manage pulmonary arterial hypertension, which is high blood pressure in the lungs. This mechanism doesn't affect brain chemistry in ways that could lead to addiction.
Is Selexipag safe for the elderly?
Elderly patients may be more vulnerable to the side effects of Selexipag, such as low blood pressure and dizziness. These effects can increase the risk of falls. It's important for elderly patients to be closely monitored by their doctor while taking Selexipag. Your doctor can adjust the dose if needed to ensure safety.
What are the most common side effects of Selexipag?
Side effects are unwanted reactions that can happen when taking a medication. Common side effects of Selexipag include headache, diarrhea, and nausea. These effects vary from person to person. If you notice new symptoms after starting Selexipag, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking Selexipag?
Don't take Selexipag if you're allergic to it or its ingredients. Serious allergic reactions require immediate medical help. Selexipag is not recommended for people with severe liver problems, which affect how the body processes the medication. Always consult your doctor about any concerns or conditions before starting Selexipag.
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