Rilpivirine
HIV Infections
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor
Controlled Drug Substance
No
rilpivirine
Summary
Rilpivirine is used to treat HIV-1 infection, which is a type of virus that attacks the immune system. It helps control the virus and improves immune function, reducing the risk of developing AIDS-related illnesses.
Rilpivirine works by blocking the reverse transcriptase enzyme, which the HIV virus needs to multiply. This action helps prevent the virus from spreading in your body, improving your immune function.
The usual dose of Rilpivirine for adults is 25 mg once daily with a meal. It's important to take it at the same time each day to maintain consistent levels in your body.
Common side effects of Rilpivirine include depression, trouble sleeping, and headache. These effects vary from person to person and are usually mild.
Rilpivirine can cause serious liver problems, so watch for symptoms like yellowing of the skin or eyes. It may also cause mood changes or depression. Avoid using it with certain medications like anticonvulsants, which can reduce its effectiveness.
Indications and Purpose
How does Rilpivirine work?
Rilpivirine works by blocking the reverse transcriptase enzyme, which the HIV virus needs to multiply. Think of it like putting a lock on a door to stop unwanted guests from entering. By blocking this enzyme, Rilpivirine helps prevent the virus from spreading in your body. This helps control the infection and improves your immune function.
Is Rilpivirine effective?
Rilpivirine is effective in treating HIV-1 infection. It works by blocking the virus from multiplying, which helps control the infection. Clinical studies show Rilpivirine effectively reduces viral load and increases CD4 cell counts in people with HIV. This helps improve immune function and overall health. Always take Rilpivirine as prescribed for the best results.
What is Rilpivirine?
Rilpivirine is a medication used to treat HIV-1 infection. It belongs to a class of drugs called non-nucleoside reverse transcriptase inhibitors, which work by blocking the virus from multiplying in your body. This helps control the infection and improves immune function. Rilpivirine is used in combination with other antiretroviral medications to effectively manage HIV.
Directions for Use
For how long do I take Rilpivirine?
Rilpivirine is usually a long-term medication for managing HIV. You'll typically take it every day as a lifelong treatment unless your doctor suggests otherwise. Stopping this medication without medical advice could cause your condition to worsen. How long you'll need this medication depends on your body's response and any side effects you experience. Always talk with your doctor before changing or stopping your Rilpivirine treatment.
How do I dispose of Rilpivirine?
If you can, bring unused Rilpivirine to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of this medicine properly so it doesn't harm people or the environment. If you can't find a take-back program, you can throw most medicines in the trash at home. But first, take them out of their original containers, mix them with something undesirable like used coffee grounds, seal the mixture in a plastic bag, and throw it away.
How do I take Rilpivirine?
Take Rilpivirine once daily with a meal. Swallow the tablet whole; do not crush or chew it. If you miss a dose and it's more than 12 hours until your next dose, take it with a meal as soon as you remember. If it's less than 12 hours, skip the missed dose and continue your regular schedule. Avoid taking two doses at once. Follow your doctor's specific advice about diet and fluid intake while taking this medication.
How long does it take for Rilpivirine to start working?
Rilpivirine starts working in your body shortly after you take it, but it may take several weeks to see significant changes in your viral load. The full therapeutic effect can take a few months. Individual factors like your overall health and adherence to the medication can affect how quickly it works. Always take Rilpivirine as prescribed for the best results.
How should I store Rilpivirine?
Store Rilpivirine at room temperature, away from moisture and light. Keep it in its original container with the lid tightly closed. Avoid storing it in humid places like bathrooms. Always keep Rilpivirine out of reach of children to prevent accidental ingestion. Check the expiration date regularly and properly dispose of any unused or expired medication.
What is the usual dose of Rilpivirine?
The usual dose of Rilpivirine for adults is 25 mg once daily with a meal. It's important to take it at the same time each day. Dose adjustments are not typically needed for special populations like the elderly, but always follow your doctor's specific dosing instructions. If you have any concerns about your dose, discuss them with your healthcare provider.
Warnings and Precautions
Can I take Rilpivirine with other prescription drugs?
Rilpivirine can interact with certain medications, such as anticonvulsants and proton pump inhibitors, which can reduce its effectiveness. These interactions can increase the risk of treatment failure. Always inform your doctor about all medications you're taking to avoid interactions. Your doctor can help adjust your treatment plan to ensure it's safe and effective.
Can Rilpivirine be taken safely while breastfeeding?
Rilpivirine is not recommended while breastfeeding. It's unclear if it passes into breast milk, but there's a risk of transmitting HIV to the baby through breast milk. If you're taking Rilpivirine and want to breastfeed, talk with your doctor about safer options. They can help you make the best decision for you and your baby.
Can Rilpivirine be taken safely while pregnant?
Rilpivirine is generally considered safe during pregnancy, but the evidence is limited. It's important to manage HIV during pregnancy to prevent transmission to the baby. Always discuss with your doctor the risks and benefits of using Rilpivirine if you're pregnant or planning to become pregnant. Your doctor can help create a treatment plan that protects both you and your baby.
Does Rilpivirine have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Rilpivirine include depression, trouble sleeping, and headache. These occur occasionally. Serious side effects like liver problems or severe skin reactions are rare but require immediate medical attention. Always inform your doctor about any new or worsening symptoms while taking Rilpivirine.
Does Rilpivirine have any safety warnings?
Yes, Rilpivirine has important safety warnings. It can cause serious liver problems, so watch for symptoms like yellowing of the skin or eyes, dark urine, or stomach pain. Rilpivirine may also cause mood changes or depression. Not adhering to these warnings can lead to severe health issues. Always follow your doctor's advice and report any unusual symptoms immediately.
Is it safe to drink alcohol while taking Rilpivirine?
It's best to limit alcohol while taking Rilpivirine. Alcohol can affect your liver, and Rilpivirine can also cause liver problems. Drinking alcohol might increase the risk of liver damage. If you choose to drink, do so in moderation and watch for symptoms like yellowing of the skin or eyes. Talk with your doctor about alcohol use while taking Rilpivirine.
Is it safe to exercise while taking Rilpivirine?
You can exercise while taking Rilpivirine. This medication doesn't typically limit exercise capacity. However, if you experience dizziness or fatigue, take a break and rest. Stay hydrated and listen to your body. If you have concerns about your specific situation, talk with your doctor. They can provide personalized advice for exercising safely while on Rilpivirine.
Is it safe to stop Rilpivirine?
Stopping Rilpivirine suddenly can cause your HIV to become resistant to treatment. This can make the virus harder to control. Always talk with your doctor before stopping Rilpivirine. They might suggest a different medication or a plan to safely stop treatment. Your doctor will help you make any medication changes safely to protect your health.
Is Rilpivirine addictive?
Rilpivirine is not addictive or habit-forming. This medication doesn't cause dependency or withdrawal symptoms when you stop taking it. Rilpivirine works by affecting the virus in your body, not your brain chemistry, so it doesn't lead to addiction. If you have concerns about medication dependence, you can feel confident that Rilpivirine doesn't carry this risk while managing your health condition.
Is Rilpivirine safe for the elderly?
Rilpivirine is generally safe for the elderly, but they may be more vulnerable to side effects like liver problems or mood changes. Older adults should be monitored closely for these effects. Always follow your doctor's advice and report any unusual symptoms. Regular check-ups help ensure the medication is safe and effective for elderly patients.
What are the most common side effects of Rilpivirine?
Side effects are unwanted reactions that can happen when taking a medication. Common side effects of Rilpivirine include depression, trouble sleeping, and headache. These effects vary from person to person. If you notice new symptoms after starting Rilpivirine, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking Rilpivirine?
Don't take Rilpivirine if you're allergic to it or its ingredients. Serious allergic reactions require immediate medical help. Rilpivirine shouldn't be used with certain medications like anticonvulsants or proton pump inhibitors, as they can reduce its effectiveness. Always consult your doctor about any other medications you're taking to avoid interactions.
