Reboxetine
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Drug Status
Government Approvals
UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
NA
Controlled Drug Substance
No
Summary
Reboxetine is used to treat major depressive disorder, which is a condition characterized by persistent sadness and a lack of interest in activities. It helps improve mood and is often part of a comprehensive treatment plan that includes therapy and lifestyle changes.
Reboxetine works by increasing the levels of norepinephrine, which is a chemical in the brain that helps improve mood. It belongs to a class of medications called selective norepinephrine reuptake inhibitors, which help reduce symptoms of depression like sadness and lack of motivation.
The usual starting dose of reboxetine for adults is 4 mg taken twice daily, once in the morning and once in the evening. It can be taken with or without food. The maximum recommended dose is 12 mg per day. Always follow your doctor's specific dosing instructions.
Common side effects of reboxetine include dry mouth, insomnia, and increased sweating. These effects occur in more than 10% of users and are usually mild. If you experience new symptoms, they might be temporary or unrelated to the medication. Always talk with your doctor before stopping any medication.
Reboxetine may increase the risk of suicidal thoughts, especially in young adults. It can also cause high blood pressure, so regular monitoring is important. Reboxetine is not recommended for people with severe liver or kidney problems. Always consult your doctor about any health concerns before starting reboxetine.
Indications and Purpose
How does reboxetine work?
Reboxetine works by increasing the levels of norepinephrine, a chemical in the brain that helps improve mood. It belongs to a class of medications called selective norepinephrine reuptake inhibitors. Think of it like a sponge that helps soak up more norepinephrine, allowing it to stay in the brain longer and improve mood. This action helps reduce symptoms of depression, such as sadness and lack of motivation. Reboxetine is effective for many people with depression, but individual responses may vary.
Is reboxetine effective?
Reboxetine is effective for treating depression. It works by increasing the levels of certain chemicals in the brain, which helps improve mood. Clinical studies show that reboxetine can significantly reduce symptoms of depression in many patients. However, individual responses may vary. It's important to take reboxetine as prescribed and attend regular check-ups with your doctor to monitor your progress. If you have concerns about the effectiveness of reboxetine, discuss them with your healthcare provider. They can adjust your treatment plan if needed.
What is reboxetine?
Reboxetine is a medication used to treat depression. It belongs to a class of drugs called selective norepinephrine reuptake inhibitors, which work by increasing the levels of norepinephrine, a chemical in the brain that helps improve mood. Reboxetine is primarily used for major depressive disorder, but it may also be prescribed for other conditions as determined by your doctor. It is usually used as part of a comprehensive treatment plan that includes therapy and lifestyle changes to manage depression effectively.
Directions for Use
For how long do I take reboxetine?
Reboxetine is usually taken long-term for managing depression. The duration of use depends on your response to the medication and your doctor's recommendations. It's important to take reboxetine as prescribed and not stop it suddenly without consulting your doctor. Stopping abruptly can worsen your condition or cause withdrawal symptoms. Your doctor will guide you on how long to take reboxetine based on your individual health needs. Always follow your healthcare provider's advice regarding medication duration.
How do I dispose of reboxetine?
To dispose of reboxetine, take it to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of it properly to prevent harm to people or the environment. If you can't find a take-back program, you can throw it in the trash at home. First, remove it from its original container, mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away. Always keep medications out of reach of children and pets.
How do I take reboxetine?
Take reboxetine as prescribed by your doctor, usually twice daily, in the morning and evening. You can take it with or without food. Do not crush or chew the tablets. If you miss a dose, take it as soon as you remember unless it's close to your next dose. In that case, skip the missed dose and continue with your regular schedule. Do not double up on doses. There are no specific dietary restrictions, but always follow your doctor's advice. If you have any questions about taking reboxetine, consult your healthcare provider.
How long does it take for reboxetine to start working?
Reboxetine may start to improve symptoms of depression within a few weeks, but it can take several weeks to achieve its full therapeutic effect. Individual responses vary, and some people may notice improvements sooner than others. Factors like age, overall health, and the severity of depression can affect how quickly reboxetine works. It's important to take the medication as prescribed and attend regular check-ups with your doctor to monitor progress. If you have concerns about how reboxetine is working, discuss them with your healthcare provider.
How should I store reboxetine?
Store reboxetine at room temperature, away from moisture and light. Keep it in a tightly closed container to protect it from damage. Do not store it in humid places like bathrooms, as moisture can affect the medication's effectiveness. Always keep reboxetine out of reach of children and pets to prevent accidental ingestion. Check the expiration date regularly and properly dispose of any unused or expired medication. If you have questions about storage, consult your pharmacist.
What is the usual dose of reboxetine?
The usual starting dose of reboxetine for adults is 4 mg twice daily, once in the morning and once in the evening. Your doctor may adjust the dose based on your response and needs. The maximum recommended dose is 12 mg per day. Reboxetine is not typically used in children, and elderly patients may require careful monitoring. Always follow your doctor's specific dosing instructions for your health needs. If you have any questions about your dose, consult your healthcare provider.
Warnings and Precautions
Can I take reboxetine with other prescription drugs?
Reboxetine can interact with other medications, increasing the risk of adverse effects. Concerning interactions include those with other antidepressants, which can increase the risk of serotonin syndrome, a condition with symptoms like confusion and rapid heart rate. Reboxetine may also interact with blood pressure medications, affecting blood pressure control. Always inform your doctor about all medications you are taking to prevent interactions. They can adjust your treatment plan to ensure safety and effectiveness.
Can reboxetine be taken safely while breastfeeding?
Reboxetine is not recommended while breastfeeding. There is limited information on whether it passes into breast milk or its effects on a breastfed infant. If you're taking reboxetine and want to breastfeed, talk with your doctor. They can discuss safer medication options that allow you to nurse your baby safely. Always consult your healthcare provider before starting or stopping any medication while breastfeeding to ensure the safety of both you and your baby.
Can reboxetine be taken safely while pregnant?
Reboxetine is not recommended during pregnancy due to limited evidence on its safety. There is not enough information about its effects on unborn babies. If you're pregnant or planning to become pregnant, talk with your doctor about the safest treatment options for your condition. They can help create a pregnancy-specific plan that protects both you and your baby. Always consult your healthcare provider before starting or stopping any medication during pregnancy.
Does reboxetine have adverse effects?
Adverse effects are unwanted reactions to a medication. Reboxetine can cause adverse effects like dry mouth, insomnia, and increased sweating. These effects are common and usually mild. Serious adverse effects, such as high blood pressure or heart palpitations, are less common but require immediate medical attention. If you experience any new or worsening symptoms, contact your doctor. They can help determine if the symptoms are related to reboxetine and adjust your treatment if necessary. Always report adverse effects to your healthcare provider.
Does reboxetine have any safety warnings?
Yes, reboxetine has important safety warnings. It may increase the risk of suicidal thoughts, especially in young adults. Monitor for mood changes or unusual behavior. Reboxetine can also cause high blood pressure, so regular monitoring is important. Not adhering to these warnings can lead to serious consequences, such as worsening depression or cardiovascular issues. Always follow your doctor's advice and report any concerning symptoms immediately. Your healthcare provider can help manage any risks associated with reboxetine.
Is it safe to drink alcohol while taking reboxetine?
It's best to avoid alcohol while taking reboxetine. Alcohol can increase the risk of side effects like dizziness and drowsiness. It may also worsen depression symptoms. If you choose to drink occasionally, limit your alcohol intake and watch for warning signs like increased dizziness or mood changes. Talk with your doctor about alcohol use while taking reboxetine to get personalized advice based on your specific health situation. Always follow your healthcare provider's recommendations.
Is it safe to exercise while taking reboxetine?
Yes, you can exercise while taking reboxetine. However, be aware that reboxetine can cause dizziness or increased heart rate, which might affect your exercise capacity. Start with light to moderate activities and listen to your body. If you feel dizzy or unusually fatigued, stop exercising and rest. Stay hydrated and avoid strenuous activities until you know how reboxetine affects you. If you have concerns about exercising while on reboxetine, talk with your doctor for personalized advice.
Is it safe to stop reboxetine?
It's not safe to stop reboxetine suddenly without consulting your doctor. Reboxetine is usually used for long-term treatment of conditions like depression. Stopping it abruptly can cause withdrawal symptoms or worsen your condition. Your doctor may suggest gradually reducing the dose to minimize risks. Always talk with your healthcare provider before making any changes to your medication. They can help you stop reboxetine safely and find alternative treatments if needed.
Is reboxetine addictive?
Reboxetine is not considered addictive or habit-forming. It does not cause physical or psychological dependence. This medication works by affecting certain chemicals in the brain to help improve mood. Unlike some medications, reboxetine does not create cravings or withdrawal symptoms when stopped. If you have concerns about medication dependence, discuss them with your doctor. They can provide reassurance and guidance on how to use reboxetine safely and effectively for your condition.
Is reboxetine safe for the elderly?
Elderly individuals are more vulnerable to medication side effects due to age-related changes in the body. Reboxetine can be used in the elderly, but with caution. They may experience increased side effects like dizziness or high blood pressure. Regular monitoring by a healthcare provider is important to ensure safety. Dose adjustments may be necessary based on individual health needs. Always consult your doctor before starting reboxetine if you are elderly or caring for an elderly person.
What are the most common side effects of reboxetine?
Side effects are unwanted reactions to a medication. Common side effects of reboxetine include dry mouth, insomnia, and increased sweating. These occur in more than 10% of users. While these side effects can be bothersome, they are usually mild and may improve over time. If you experience new symptoms after starting reboxetine, they might be temporary or unrelated to the medication. Always talk with your doctor before stopping any medication. They can help determine if the side effects are related to reboxetine and suggest ways to manage them.
Who should avoid taking reboxetine?
Reboxetine should not be used if you are allergic to it or its ingredients. This is an absolute contraindication. Serious allergic reactions require immediate medical help. Reboxetine is also not recommended for people with severe liver or kidney problems, as it may worsen these conditions. Use caution if you have a history of seizures or heart problems. Always consult your doctor about any health concerns before starting reboxetine. They can help determine if this medication is safe for you.
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