Quinapril
Hypertension, Left Ventricular Dysfunction ... show more
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
Possible
Pharmaceutical Class
Angiotensin Converting Enzyme Inhibitor
Controlled Drug Substance
No
quinapril
Summary
Quinapril is used to treat high blood pressure, which is when the force of blood against artery walls is too high, and heart failure, which is when the heart can't pump blood effectively. It also helps protect the kidneys in people with diabetes, which is a condition where blood sugar levels are too high.
Quinapril works by relaxing blood vessels, which are the tubes that carry blood throughout the body. This action lowers blood pressure and improves blood flow, making it easier for the heart to pump blood. It blocks a chemical that tightens blood vessels, helping to treat high blood pressure and heart failure.
The usual starting dose of Quinapril for adults is 10 to 20 mg once daily. Your doctor may adjust the dose based on your response, with a maximum of 80 mg per day. It is taken by mouth, which means swallowing the tablet whole with water, and can be taken with or without food.
Common side effects of Quinapril include dizziness, which is a feeling of being unsteady, headache, which is pain in the head, and fatigue, which is feeling very tired. These effects are not common and usually mild. If you experience any of these, talk to your doctor for advice.
Quinapril should not be used if you are allergic to it or have had angioedema, which is swelling under the skin, from ACE inhibitors. It is not recommended during pregnancy, especially in later stages, as it can harm the unborn baby. Always follow your doctor's advice and report any unusual symptoms.
Indications and Purpose
How does Quinapril work?
Quinapril is an ACE inhibitor that works by blocking a chemical in the body that tightens blood vessels. This action relaxes the blood vessels, lowering blood pressure and improving blood flow. Think of it like opening a valve to let water flow more easily through a pipe. This helps treat high blood pressure and heart failure.
Is Quinapril effective?
Quinapril is effective for treating high blood pressure and heart failure. It works by relaxing blood vessels, which lowers blood pressure and improves blood flow. Clinical studies show Quinapril effectively reduces blood pressure and improves heart function, leading to better health outcomes for patients with these conditions.
What is Quinapril?
Quinapril is an ACE inhibitor used to treat high blood pressure and heart failure. It works by relaxing blood vessels, which lowers blood pressure and improves blood flow. Quinapril is also used to protect the kidneys in people with diabetes. It can be used alone or with other medications to manage these conditions.
Directions for Use
For how long do I take Quinapril?
Quinapril is usually a long-term medication for managing conditions like hypertension and heart failure. You'll typically take it every day as a lifelong treatment unless your doctor suggests otherwise. Stopping Quinapril without medical advice could worsen your condition. Always talk with your doctor before changing or stopping your treatment.
How do I dispose of Quinapril?
Dispose of unused Quinapril by taking it to a drug take-back program or collection site at a pharmacy or hospital. If unavailable, mix the medication with an undesirable substance like used coffee grounds, seal it in a plastic bag, and throw it in the trash. This prevents harm to people and the environment.
How do I take Quinapril?
Take Quinapril as prescribed by your doctor, usually once or twice daily. It can be taken with or without food. Swallow the tablet whole; do not crush it. If you miss a dose, take it as soon as you remember, unless it's close to your next dose. In that case, skip the missed dose. Do not double up on doses. Avoid alcohol and follow any dietary restrictions your doctor advises.
How long does it take for Quinapril to start working?
Quinapril starts working within an hour, but it may take several weeks to achieve its full effect. Blood pressure improvements can be seen within a few days, but heart failure benefits may take longer. Factors like age, kidney function, and overall health can affect how quickly Quinapril works. Take it as prescribed for the best results.
How should I store Quinapril?
Store Quinapril at room temperature, away from moisture and light. Keep it in a tightly closed container. Do not store it in humid places like bathrooms, as moisture can affect the medication's effectiveness. Always keep Quinapril out of children's reach to prevent accidental ingestion. Check expiration dates and dispose of expired medication properly.
What is the usual dose of Quinapril?
The usual starting dose of Quinapril for adults is 10 to 20 mg once daily. Your doctor may adjust the dose based on your response and needs, with a maximum recommended dose of 80 mg per day. For elderly patients or those with kidney issues, dose adjustments may be necessary. Always follow your doctor's specific dosing instructions.
Warnings and Precautions
Can I take Quinapril with other prescription drugs?
Quinapril can interact with other medications, increasing the risk of adverse effects. Combining it with diuretics can lead to low blood pressure. Nonsteroidal anti-inflammatory drugs (NSAIDs) may reduce its effectiveness. Potassium supplements or potassium-sparing diuretics can cause high potassium levels. Always inform your doctor about all medications you take to avoid interactions.
Can Quinapril be taken safely while breastfeeding?
Quinapril is not recommended while breastfeeding. Limited information is available on whether it passes into breast milk, but it may pose risks to the infant. If you are breastfeeding or planning to breastfeed, discuss safer medication options with your doctor to ensure your baby's safety.
Can Quinapril be taken safely while pregnant?
Quinapril is not recommended during pregnancy, especially in the second and third trimesters, as it can harm the unborn baby. It may affect kidney development and lead to birth defects. If you are pregnant or planning to become pregnant, talk with your doctor about safer alternatives to manage your condition.
Does Quinapril have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Quinapril include dizziness, headache, and fatigue. Serious effects, though rare, include angioedema, which is swelling under the skin, and high potassium levels. If you notice any adverse effects, contact your doctor immediately for advice and possible treatment adjustments.
Does Quinapril have any safety warnings?
Yes, Quinapril has safety warnings. It can cause low blood pressure, especially when starting treatment or increasing the dose. It may also lead to high potassium levels, which can be dangerous. Not following these warnings can result in serious health issues. Always follow your doctor's advice and report any unusual symptoms.
Is it safe to drink alcohol while taking Quinapril?
It's best to limit alcohol while taking Quinapril. Alcohol can lower blood pressure further, increasing the risk of dizziness or fainting. It may also worsen side effects like dizziness. If you choose to drink, do so in moderation and monitor for any symptoms. Discuss alcohol use with your doctor for personalized advice.
Is it safe to exercise while taking Quinapril?
Yes, you can exercise while taking Quinapril. However, Quinapril can cause dizziness, especially when starting treatment. Stay hydrated and avoid strenuous activities if you feel dizzy. Monitor your body's response during exercise and stop if you experience unusual symptoms. Consult your doctor if you have concerns about your exercise routine.
Is it safe to stop Quinapril?
Quinapril is usually used long-term for conditions like hypertension. Stopping it suddenly can cause your blood pressure to rise, increasing the risk of heart attack or stroke. Always consult your doctor before stopping Quinapril. They may suggest a gradual reduction or an alternative treatment to manage your condition safely.
Is Quinapril addictive?
Quinapril is not addictive or habit-forming. It does not cause dependency or withdrawal symptoms. Quinapril works by relaxing blood vessels to lower blood pressure, which does not affect brain chemistry in a way that leads to addiction. You can stop taking it without experiencing cravings or withdrawal, but always consult your doctor before stopping.
Is Quinapril safe for the elderly?
Elderly patients are more vulnerable to Quinapril's side effects, such as dizziness and high potassium levels. They may also have other health conditions that require careful monitoring. Quinapril is generally safe for the elderly when used under a doctor's supervision. Regular check-ups and dose adjustments may be necessary to ensure safety.
What are the most common side effects of Quinapril?
Side effects are unwanted reactions to a medication. Common side effects of Quinapril include dizziness, headache, and fatigue. These occur in a small percentage of users. If you experience new symptoms after starting Quinapril, they might be temporary or unrelated. Always talk with your doctor before stopping any medication.
Who should avoid taking Quinapril?
Do not use Quinapril if you are allergic to it or its ingredients. It is contraindicated in patients with a history of angioedema related to previous ACE inhibitor treatment. Quinapril should not be used during pregnancy, especially in the second and third trimesters, as it can harm the unborn baby. Always consult your doctor about any concerns.
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