Podofilox
Warts
Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
NA
Controlled Drug Substance
No
Summary
Podofilox is used to treat external genital warts, which are growths caused by certain types of human papillomavirus (HPV). It helps by stopping the growth of wart cells, causing them to shrink and eventually disappear.
Podofilox works by stopping the growth of wart cells. It belongs to a class of medications called antimitotics, which interfere with cell division, causing the warts to shrink and eventually disappear.
Podofilox is applied directly to the affected area twice daily, in the morning and evening, for three days, followed by four days without treatment. This cycle may be repeated up to four times if needed.
Common adverse effects of podofilox include local skin reactions like redness, itching, or burning at the application site. These effects are usually mild and temporary.
Podofilox is for external use only and should not be applied to healthy skin, eyes, or mucous membranes, which are moist tissues lining body cavities. Pregnant or breastfeeding women should consult their doctor before using podofilox.
Indications and Purpose
How does podofilox work?
Podofilox works by stopping the growth of wart cells. It belongs to a class of medications called antimitotics, which interfere with cell division. Think of it like a roadblock that prevents wart cells from multiplying. This action causes the warts to shrink and eventually disappear. Podofilox is effective for treating external genital warts, which are growths caused by certain types of human papillomavirus (HPV).
Is podofilox effective?
Podofilox is effective for treating external genital warts, which are growths caused by certain types of human papillomavirus (HPV). It works by stopping the growth of wart cells. Clinical studies show that podofilox can significantly reduce the size and number of warts. However, it may not work for everyone, and warts can return after treatment. Always follow your doctor's instructions for the best results.
What is podofilox?
Podofilox is a topical medication used to treat external genital warts, which are growths caused by certain types of human papillomavirus (HPV). It belongs to a class of medications called antimitotics, which stop the growth of wart cells. Podofilox is applied directly to the warts, causing them to shrink and eventually disappear. It's used as a complementary treatment to other therapies, like cryotherapy or surgical removal.
Directions for Use
For how long do I take podofilox?
Podofilox is used for short-term treatment of warts. Typically, you apply it for three days, followed by four days without treatment. This cycle may be repeated up to four times if needed. The duration depends on your response to treatment and your doctor's advice. Always follow your doctor's instructions for the best results.
How do I dispose of podofilox?
To dispose of podofilox, bring unused medicine to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of it properly to prevent harm to people or the environment. If you can't find a take-back program, you can throw it in the trash at home. First, mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away.
How do I take podofilox?
Podofilox is usually applied directly to the affected area. Follow your doctor's instructions on how to use it. Typically, you apply it twice daily, in the morning and evening, for three days, followed by four days without treatment. Do not crush or ingest it. Avoid contact with healthy skin and wash your hands after application. If you miss a dose, apply it as soon as you remember, unless it's almost time for the next dose. Never double up on doses.
How long does it take for podofilox to start working?
Podofilox starts working soon after application, but visible results may take a few days. You might notice redness or irritation at the application site, which indicates the medication is affecting the wart tissue. Complete wart removal may take several treatment cycles, depending on the size and number of warts. Follow your doctor's instructions for the best results.
How should I store podofilox?
Store podofilox at room temperature, away from light and moisture. Keep it in a tightly closed container to protect it from damage. Don't store it in humid places like bathrooms, where moisture in the air could affect how well the medication works. Always keep podofilox out of children's reach to prevent accidental use. Check the expiration date regularly and dispose of any unused or expired medication properly.
What is the usual dose of podofilox?
The usual dose of podofilox for adults is to apply it to the affected area twice daily, in the morning and evening, for three consecutive days, followed by four days without treatment. This cycle may be repeated up to four times if needed. Always follow your doctor's specific dosing instructions. Podofilox is not typically used in children, and elderly patients should use it with caution.
Warnings and Precautions
Can I take podofilox with other prescription drugs?
Podofilox is applied topically and doesn't have significant interactions with other prescription drugs. However, it's always important to inform your doctor about all medications you're taking. This helps ensure your treatment is safe and effective. If you have concerns about drug interactions, talk with your doctor for personalized advice.
Can podofilox be taken safely while breastfeeding?
Podofilox is not recommended while breastfeeding. There's limited information on whether it passes into breast milk, and it may pose risks to the nursing infant. If you're breastfeeding and need treatment, talk with your doctor about safer options. They can help you choose a medication that allows you to nurse your baby safely.
Can podofilox be taken safely while pregnant?
Podofilox is not recommended during pregnancy. There's limited evidence on its safety for pregnant women, and it may pose risks to the developing baby. If you're pregnant or planning to become pregnant, talk with your doctor about safer treatment options. They can help create a plan that protects both you and your baby.
Does podofilox have adverse effects?
Adverse effects are unwanted reactions to a medication. With podofilox, common adverse effects include local skin reactions like redness, itching, or burning at the application site. These effects are usually mild and temporary. Severe skin reactions are rare but require immediate medical attention. If you notice any new or worsening symptoms, contact your doctor. They can help determine if these symptoms are related to podofilox and suggest appropriate actions.
Does podofilox have any safety warnings?
Yes, podofilox has safety warnings. It is for external use only and should not be applied to healthy skin, eyes, or mucous membranes, which are moist tissues lining body cavities. Avoid using it on large areas of skin. Overuse can lead to severe skin reactions. If you experience severe irritation, stop using it and contact your doctor. Pregnant or breastfeeding women should consult their doctor before using podofilox.
Is it safe to drink alcohol while taking podofilox?
There's no known interaction between podofilox and alcohol. However, it's always best to use alcohol in moderation. Excessive alcohol consumption can affect your overall health and may interfere with your body's ability to heal. If you have concerns about alcohol use while using podofilox, talk with your doctor for personalized advice.
Is it safe to exercise while taking podofilox?
Yes, it's safe to exercise while using podofilox. This medication is applied to the skin and doesn't affect your ability to exercise. However, if you experience skin irritation or discomfort at the application site, you might want to avoid activities that cause friction or sweating in that area. Listen to your body and adjust your exercise routine as needed.
Is it safe to stop podofilox?
Yes, it's safe to stop using podofilox once your treatment cycle is complete or if your doctor advises you to stop. Podofilox is typically used for short-term treatment of skin conditions like warts. Stopping it won't cause withdrawal symptoms. However, if you stop before the end of the treatment cycle, the condition may not fully resolve. Always follow your doctor's instructions for the best results.
Is podofilox addictive?
Podofilox is not addictive or habit-forming. It doesn't cause dependency or withdrawal symptoms when you stop using it. Podofilox works by affecting the skin cells where it's applied, not the brain, so it doesn't lead to addiction. You won't experience cravings for this medication or feel compelled to use more than prescribed. If you have concerns about medication dependence, podofilox doesn't carry this risk.
Is podofilox safe for the elderly?
Podofilox is generally safe for elderly patients, but they may be more sensitive to its effects. The elderly are more vulnerable to skin irritation, which is a common side effect. It's important to use podofilox as directed and monitor for any adverse reactions. If you have concerns about using podofilox, talk with your doctor for personalized advice.
What are the most common side effects of podofilox?
Side effects are unwanted reactions that can happen when using a medication. With podofilox, common side effects include redness, itching, or burning at the application site. These effects are usually mild and temporary. If you notice new symptoms after starting podofilox, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking podofilox?
Podofilox should not be used if you're allergic to it or its ingredients. Avoid using it on healthy skin, eyes, or mucous membranes, which are moist tissues lining body cavities. It's not recommended for pregnant or breastfeeding women without a doctor's advice. People with large areas of warts should use it cautiously. Always consult your doctor about any concerns before using podofilox.

