Permethrin

English

Brand Name

Scrabel Soap , Perlice Cream 120gm ... show more

Approved Treatment Indication:

Scabies, Lice Infestations

Listen

What conditions permethrin is used for
Permethrin is used to treat scabies and lice infestations. Scabies is a skin condition caused by mites, which are tiny insects that burrow into the skin, causing itching and rash. Lice are small insects that infest the hair and scalp, causing itching and discomfort. Permethrin effectively eliminates these parasites.
How permethrin works in the body
Permethrin works by affecting the nervous system of parasites like mites and lice. It paralyzes and kills them by disrupting their nerve function, which is how nerves send signals. This action effectively eliminates the infestation, providing relief from symptoms and preventing reinfestation.
The usual dosages and routes of administration of permethrin
Permethrin is usually applied as a 5% cream or lotion. For scabies, it's applied to the entire body from the neck down and left on for 8 to 14 hours before washing off. For lice, it's applied to the hair and scalp, left for 10 minutes, then rinsed out.
The most commonly observed adverse effects of permethrin
Common side effects of permethrin include mild skin irritation, redness, or itching at the application site. These effects are usually temporary and resolve on their own. Serious adverse effects are rare but can include severe allergic reactions, which require immediate medical attention.
Important safety warnings and contraindications of permethrin
Permethrin should not be used if you're allergic to it or its ingredients. Avoid contact with eyes, nose, and mouth, as it can cause irritation. Use it only on the skin and not on open wounds. If severe skin irritation or an allergic reaction occurs, stop using permethrin and seek medical help.

Government Approvals

US(FDA), UK(BNF)

WHO Essential Medicine

Known Teratogen

Pharmaceutical Class

Pyrethroid

Controlled Drug Substance

Summary

What conditions permethrin is used for
Permethrin is used to treat scabies and lice infestations. Scabies is a skin condition caused by mites, which are tiny insects that burrow into the skin, causing itching and rash. Lice are small insects that infest the hair and scalp, causing itching and discomfort. Permethrin effectively eliminates these parasites.
How permethrin works in the body
Permethrin works by affecting the nervous system of parasites like mites and lice. It paralyzes and kills them by disrupting their nerve function, which is how nerves send signals. This action effectively eliminates the infestation, providing relief from symptoms and preventing reinfestation.
The usual dosages and routes of administration of permethrin
Permethrin is usually applied as a 5% cream or lotion. For scabies, it's applied to the entire body from the neck down and left on for 8 to 14 hours before washing off. For lice, it's applied to the hair and scalp, left for 10 minutes, then rinsed out.
The most commonly observed adverse effects of permethrin
Common side effects of permethrin include mild skin irritation, redness, or itching at the application site. These effects are usually temporary and resolve on their own. Serious adverse effects are rare but can include severe allergic reactions, which require immediate medical attention.
Important safety warnings and contraindications of permethrin
Permethrin should not be used if you're allergic to it or its ingredients. Avoid contact with eyes, nose, and mouth, as it can cause irritation. Use it only on the skin and not on open wounds. If severe skin irritation or an allergic reaction occurs, stop using permethrin and seek medical help.

Indications and Purpose

How does permethrin work?

Permethrin works by affecting the nervous system of parasites like mites and lice. It paralyzes and kills them by disrupting their nerve function. Think of it like a bug zapper that targets the pests' nervous systems. This action effectively eliminates the infestation. Permethrin is applied to the skin or hair, where it comes into contact with the parasites. It's effective for treating scabies and lice, providing relief from symptoms and preventing reinfestation.

Is permethrin effective?

Yes, permethrin is effective for treating scabies and lice. It works by paralyzing and killing the parasites. Clinical studies show that permethrin is highly effective in eliminating scabies mites and lice with a single application. For scabies, it usually relieves itching and clears the infestation within a few days. For lice, it kills the lice and their eggs, preventing further infestation. Always follow your doctor's instructions for the best results.

What is permethrin?

Permethrin is a medication used to treat scabies and lice. It's a topical insecticide that belongs to the pyrethroid class. Permethrin works by paralyzing and killing parasites like mites and lice. It's applied to the skin or hair, depending on the condition being treated. Permethrin is effective in eliminating infestations and is often used as a first-line treatment. Always follow your doctor's instructions for safe and effective use.

Directions for Use

For how long do I take permethrin?

Permethrin is used for short-term treatment of conditions like scabies or lice. Typically, it's applied as a single treatment, but your doctor may recommend a second application if needed. The duration of use depends on the condition being treated and your doctor's instructions. Always follow your doctor's guidance on how long to use permethrin. Completing the full course of treatment ensures the best results and prevents reinfestation.

How do I dispose of permethrin?

Dispose of unused permethrin by taking it to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of it properly to prevent harm to people or the environment. If you can't find a take-back program, you can throw it in the trash at home. First, take it out of its original container, mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away.

How do I take permethrin?

Permethrin is usually applied as a topical cream or lotion. Follow your doctor's instructions on how to use it. Typically, you apply it to clean, dry skin, covering the affected area. Leave it on for the recommended time, usually 8 to 14 hours, before washing it off. Avoid contact with eyes, nose, and mouth. If you miss a dose, apply it as soon as you remember, but don't double up. Always follow your doctor's specific advice for your treatment.

How long does it take for permethrin to start working?

Permethrin starts working immediately after application. For scabies, itching and rash usually improve within a few days. For lice, you should see dead lice and nits after treatment. The full therapeutic effect may take a week or more, depending on the severity of the infestation. Factors like skin sensitivity and the extent of the infestation can affect how quickly you see results. Always follow your doctor's instructions for the best outcome.

How should I store permethrin?

Store permethrin at room temperature, away from heat and direct light. Keep it in a tightly closed container to protect it from moisture. Don't store it in the bathroom, where humidity can affect it. If the packaging isn't child-resistant, transfer it to a container that children can't easily open. Always keep permethrin out of children's reach to prevent accidental use. Check the expiration date regularly and dispose of any unused or expired medication properly.

What is the usual dose of permethrin?

The usual dose of permethrin for adults is a 5% cream or lotion applied to the skin. It's typically used as a single application, covering the entire body from the neck down. For children, the dose may vary based on age and weight, so follow your doctor's instructions. Permethrin is not usually adjusted for the elderly, but they should be monitored for skin reactions. Always follow your doctor's specific dosing instructions.

Warnings and Precautions

Can I take permethrin with other prescription drugs?

Permethrin is a topical medication, so it doesn't have significant interactions with prescription drugs. It works on the skin and doesn't enter the bloodstream in significant amounts. However, always inform your doctor about all the medications you're taking, including topical treatments. This helps ensure your treatment is safe and effective. If you have concerns about specific drug interactions, discuss them with your healthcare provider.

Can permethrin be taken safely while breastfeeding?

Permethrin is generally considered safe to use while breastfeeding. It is minimally absorbed into the bloodstream, so it is unlikely to affect breast milk or the breastfed infant. However, always consult your doctor before using any medication while breastfeeding. They can provide personalized advice based on your specific health needs. If you have concerns about using permethrin while nursing, discuss them with your healthcare provider.

Can permethrin be taken safely while pregnant?

Permethrin is generally considered safe to use during pregnancy. Limited evidence suggests it doesn't pose significant risks to the unborn baby. However, always consult your doctor before using any medication during pregnancy. They can provide personalized advice based on your specific health needs. If you're pregnant or planning to become pregnant, discuss the safest treatment options with your healthcare provider.

Does permethrin have adverse effects?

Adverse effects are unwanted reactions to a medication. With permethrin, common adverse effects include mild skin irritation, redness, or itching at the application site. These effects are usually temporary. Serious adverse effects are rare but can include severe allergic reactions. If you notice severe skin reactions or signs of an allergic reaction, such as rash or difficulty breathing, seek medical attention immediately. Always inform your doctor of any new or worsening symptoms.

Does permethrin have any safety warnings?

Yes, permethrin has safety warnings. Avoid contact with eyes, nose, and mouth, as it can cause irritation. Use it only on the skin and not on open wounds. If you experience severe skin irritation or an allergic reaction, stop using permethrin and seek medical help. Not adhering to these warnings can lead to increased irritation or allergic reactions. Always follow your doctor's instructions and read the medication guide carefully.

Is it safe to drink alcohol while taking permethrin?

Yes, you can drink alcohol while using permethrin. There are no known interactions between alcohol and permethrin, as permethrin is a topical medication. However, always use alcohol in moderation and follow your doctor's advice regarding alcohol consumption. If you have concerns about alcohol use while using permethrin, discuss them with your healthcare provider for personalized advice.

Is it safe to exercise while taking permethrin?

Yes, it's safe to exercise while using permethrin. This medication is applied to the skin and doesn't affect your ability to exercise. However, avoid activities that cause excessive sweating immediately after application, as this might reduce the medication's effectiveness. If you experience skin irritation or other symptoms during exercise, talk with your doctor. They can provide guidance on managing any issues while continuing your treatment.

Is it safe to stop permethrin?

Yes, it's safe to stop using permethrin once your treatment is complete. Permethrin is typically used for short-term treatment of conditions like scabies or lice. Stopping it after the recommended duration won't cause withdrawal symptoms. However, if you stop using it before the end of the treatment course, the condition might not be fully resolved. Always follow your doctor's instructions and complete the full course of treatment for the best results.

Is permethrin addictive?

No, permethrin is not addictive. It doesn't have habit-forming potential or cause dependency. Permethrin works by affecting the nervous system of parasites, not humans, so it doesn't influence brain chemistry in a way that could lead to addiction. You won't experience cravings or withdrawal symptoms when you stop using it. If you have concerns about medication dependence, rest assured that permethrin doesn't carry this risk.

Is permethrin safe for the elderly?

Yes, permethrin is generally safe for the elderly. However, older adults may have more sensitive skin, which can increase the risk of irritation. It's important to follow the application instructions carefully and monitor for any skin reactions. If irritation occurs, consult your doctor. They can provide guidance on managing any issues and ensure the treatment is safe and effective for elderly patients.

What are the most common side effects of permethrin?

Side effects are unwanted reactions to a medication. Common side effects of permethrin include mild skin irritation, redness, or itching where it's applied. These effects are usually temporary and resolve on their own. If you notice new symptoms after starting permethrin, they might be unrelated to the medication. Talk with your doctor if you have concerns or if the side effects persist. They can help determine if the symptoms are related to permethrin.

Who should avoid taking permethrin?

Permethrin should not be used if you're allergic to it or its ingredients. Serious allergic reactions, which cause rash, hives, or swelling that makes breathing difficult, require immediate medical help. Use caution if you have sensitive skin or a history of skin reactions. Permethrin is generally safe for most people, but always consult your doctor if you have concerns or if you're using it on infants or young children.