Patiromer
Hyperkalemia
Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Potassium Binder
Controlled Drug Substance
No
Summary
Patiromer is used to treat high potassium levels, which is called hyperkalemia. It helps manage potassium levels in patients with chronic kidney disease or heart failure, preventing complications like heart problems.
Patiromer works by binding to potassium in the gut, which helps remove excess potassium from the body through the stool. This process lowers high potassium levels and prevents complications.
The usual starting dose of patiromer for adults is 8.4 grams once daily, taken with food. Your doctor may adjust the dose based on your potassium levels. Do not crush or chew the medication.
Common side effects of patiromer include constipation and low magnesium levels, which may cause muscle cramps or weakness. These effects are generally mild and occur in a small percentage of people.
Patiromer can cause low magnesium levels, so regular monitoring is important. It should not be used if you have a bowel obstruction, which is a blockage in the intestines, due to severe risks.
Indications and Purpose
How does patiromer work?
Patiromer works by binding to potassium in the gut, which helps remove excess potassium from the body through the stool. Think of it like a sponge soaking up extra potassium. This process helps lower high potassium levels, which is called hyperkalemia, and prevents complications such as heart problems. Patiromer is effective in managing potassium levels in patients with chronic kidney disease or heart failure.
Is patiromer effective?
Patiromer is effective in treating high potassium levels, which is called hyperkalemia. Clinical studies show that patiromer significantly lowers potassium levels in patients with chronic kidney disease or heart failure. This helps prevent complications associated with high potassium, such as heart problems. Patiromer is a reliable option for managing hyperkalemia.
What is patiromer?
Patiromer is a medication used to treat high potassium levels, which is called hyperkalemia. It belongs to a class of medicines called potassium binders. Patiromer works by binding to potassium in the gut, which helps remove excess potassium from the body through the stool. This helps prevent complications associated with high potassium, such as heart problems.
Directions for Use
For how long do I take patiromer?
Patiromer is usually a long-term medication for managing high potassium levels, which is called hyperkalemia. You'll typically take patiromer every day as a lifelong treatment unless your doctor suggests otherwise. How long you'll need this medication depends on your body's response, any side effects you experience, and changes in your overall health. Always talk with your doctor before changing or stopping your patiromer treatment.
How do I dispose of patiromer?
If you can, bring unused patiromer to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of this medicine properly so it doesn't harm people or the environment. If you can't find a take-back program, you can throw most medicines in the trash at home. But first, take them out of their original containers, mix them with something undesirable like used coffee grounds, seal the mixture in a plastic bag, and throw it away.
How do I take patiromer?
Take patiromer as directed by your doctor, usually once daily. It should be taken with food. Do not crush or chew the medication. If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not take two doses at once. Follow any dietary or beverage restrictions your doctor advises.
How long does it take for patiromer to start working?
Patiromer starts working in your body within hours of taking it. It begins to lower potassium levels, which is called hyperkalemia, soon after administration. However, the full therapeutic effect may take a few days to become noticeable. How quickly it works can depend on your overall health and potassium levels. Take it exactly as prescribed for the best results.
How should I store patiromer?
Store patiromer at room temperature, away from moisture and light. Keep it in its original container with the lid tightly closed. Do not store it in humid places like bathrooms. Always keep patiromer out of reach of children to prevent accidental ingestion. Check the expiration date regularly and properly dispose of any unused or expired medication.
What is the usual dose of patiromer?
The usual starting dose of patiromer for adults is 8.4 grams once daily. Your doctor may adjust your dose based on your potassium levels and how you respond to the medication. The maximum recommended dose is 25.2 grams per day. Always follow your doctor's specific dosing instructions for your personal health needs.
Warnings and Precautions
Can I take patiromer with other prescription drugs?
Patiromer can interact with other medications by binding to them in the gut, reducing their effectiveness. To prevent this, take patiromer at least 3 hours before or after other medications. Always inform your doctor about all the medications you are taking to avoid potential interactions and ensure effective treatment.
Can patiromer be taken safely while breastfeeding?
The safety of patiromer while breastfeeding is not well-established. It's unclear if patiromer passes into breast milk. If you're breastfeeding or planning to breastfeed, talk with your doctor about the safest way to manage your potassium levels. Your doctor can help create a treatment plan that protects both you and your baby.
Can patiromer be taken safely while pregnant?
The safety of patiromer during pregnancy is not well-established. Limited data is available, so it's important to weigh the benefits and risks with your doctor. If you're pregnant or planning to become pregnant, discuss with your doctor the safest way to manage your potassium levels during this time.
Does patiromer have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of patiromer include constipation and low magnesium levels. These effects are generally mild. Serious side effects are rare but can include severe allergic reactions. If you notice any new or worsening symptoms, contact your doctor immediately for advice.
Does patiromer have any safety warnings?
Yes, patiromer has safety warnings. It can cause low magnesium levels, which may lead to muscle cramps or weakness. Not adhering to safety warnings can result in serious health issues. Always follow your doctor's instructions and report any unusual symptoms. Regular monitoring of your blood levels is important while taking this medication.
Is it safe to drink alcohol while taking patiromer?
There's no well-established interaction between patiromer and alcohol. However, it's always best to drink alcohol in moderation and discuss your alcohol use with your doctor. Alcohol can affect your overall health and may interact with other medications you are taking. Your doctor can provide personalized advice based on your specific health situation.
Is it safe to exercise while taking patiromer?
You can exercise while taking patiromer, but keep a few things in mind. Patiromer can cause constipation, which might make you feel uncomfortable during exercise. To exercise safely, drink plenty of water before, during, and after physical activity. If you notice any unusual symptoms, slow down or stop exercising and rest. Check with your doctor if you have concerns about your specific situation.
Is it safe to stop patiromer?
Patiromer is usually used long-term for managing high potassium levels. Stopping it suddenly can cause your potassium levels to rise, which can be dangerous. Always talk with your doctor before stopping patiromer. They might suggest gradually reducing your dose or switching to a different medication to keep your condition under control.
Is patiromer addictive?
Patiromer is not addictive or habit-forming. This medication doesn't cause dependency or withdrawal symptoms when you stop taking it. Patiromer works by binding potassium in the gut, which doesn't affect brain chemistry in ways that could lead to addiction. You won't experience cravings for this medication or feel compelled to take more than prescribed.
Is patiromer safe for the elderly?
Elderly individuals may be more vulnerable to the side effects of medications. Patiromer is generally safe for the elderly, but they may experience constipation more frequently. Regular monitoring of potassium and magnesium levels is important. Always consult your doctor about any concerns and follow their specific advice for safe use.
What are the most common side effects of patiromer?
Side effects are unwanted reactions that can happen when taking a medication. Common side effects of patiromer include constipation and low magnesium levels. These effects are generally mild and occur in a small percentage of people. If you notice new symptoms after starting patiromer, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking patiromer?
Patiromer should not be used if you have a bowel obstruction, which is a blockage in the intestines. This is an absolute contraindication due to severe risks. Use caution if you have severe constipation or gastrointestinal motility disorders. Always consult your doctor about these concerns before starting patiromer.