Nimodipine
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Calcium Channel Blocker
Controlled Drug Substance
No
nimodipine
Summary
Nimodipine is used to treat subarachnoid hemorrhage, which is a type of brain bleed. It helps improve blood flow in the brain and reduces the risk of complications after such hemorrhages.
Nimodipine works by blocking calcium channels in the brain's blood vessels, which helps them relax and widen. This improves blood flow and reduces the risk of complications after a subarachnoid hemorrhage.
The usual dose of Nimodipine for adults is 60 mg every 4 hours, taken by mouth. The maximum recommended dose is 360 mg per day. It should be taken on an empty stomach, either 1 hour before or 2 hours after meals.
Common side effects of Nimodipine include dizziness, headache, and flushing, which refers to a warm, red feeling in the skin. These effects are usually mild and temporary.
Nimodipine should not be used if you are allergic to it. It is contraindicated for intravenous use due to severe risks. Caution is needed if you have low blood pressure or liver problems.
Indications and Purpose
How does Nimodipine work?
Nimodipine works by blocking calcium channels in the brain's blood vessels, which helps them relax and widen. This improves blood flow and reduces the risk of complications after a subarachnoid hemorrhage, which is a type of brain bleed. Think of it like opening a clogged pipe to allow water to flow freely.
Is Nimodipine effective?
Nimodipine is effective in improving outcomes after a specific type of brain hemorrhage called subarachnoid hemorrhage. It works by relaxing blood vessels in the brain, improving blood flow, and reducing the risk of complications. Clinical studies support its effectiveness in reducing the risk of brain damage after such hemorrhages.
What is Nimodipine?
Nimodipine is a calcium channel blocker, which is a type of medication that relaxes blood vessels. It's primarily used to treat subarachnoid hemorrhage, which is a type of brain bleed. By improving blood flow in the brain, it helps reduce the risk of complications after such hemorrhages.
Directions for Use
For how long do I take Nimodipine?
Nimodipine is usually taken for a short period, typically 21 days, after a subarachnoid hemorrhage, which is a type of brain bleed. The duration may vary based on your condition and doctor's advice. Always follow your doctor's instructions regarding how long to take Nimodipine.
How do I dispose of Nimodipine?
Dispose of Nimodipine by taking it to a drug take-back program or collection site at a pharmacy or hospital. If unavailable, mix it with undesirable substances like used coffee grounds, seal it in a plastic bag, and throw it in the trash. This prevents harm to people and the environment.
How do I take Nimodipine?
Take Nimodipine as prescribed by your doctor. It's usually taken every 4 hours, and you should swallow the capsules whole with water. Do not crush or chew them. Take it on an empty stomach, either 1 hour before or 2 hours after meals. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Avoid grapefruit juice while taking this medication.
How long does it take for Nimodipine to start working?
Nimodipine starts working within a few hours of taking it. However, the full therapeutic effect, especially for preventing complications after a subarachnoid hemorrhage, may take several days. Individual factors like age and overall health can affect how quickly you notice benefits. Follow your doctor's instructions for best results.
How should I store Nimodipine?
Store Nimodipine at room temperature, away from light and moisture. Keep it in a tightly closed container. Avoid storing it in humid places like bathrooms. Always keep it out of reach of children and check the expiration date regularly. Dispose of any unused or expired medication properly.
What is the usual dose of Nimodipine?
The usual dose of Nimodipine for adults is 60 mg every 4 hours. This dose may be adjusted by your doctor based on your condition and response to treatment. The maximum recommended dose is 360 mg per day. Always follow your doctor's specific dosing instructions for your health needs.
Warnings and Precautions
Can I take Nimodipine with other prescription drugs?
Nimodipine can interact with other medications, increasing the risk of side effects. Major interactions include drugs that affect liver enzymes, like certain antibiotics and antifungals, which can alter Nimodipine levels. Always inform your doctor about all medications you're taking to avoid potential interactions.
Can Nimodipine be taken safely while breastfeeding?
Nimodipine's safety during breastfeeding isn't well-established. It's unclear if it passes into breast milk or affects the infant. Discuss with your doctor whether to use Nimodipine while breastfeeding, considering the potential risks and benefits for you and your baby.
Can Nimodipine be taken safely while pregnant?
Nimodipine's safety during pregnancy isn't well-established. Limited data is available, so it's important to weigh the benefits and risks with your doctor. If you're pregnant or planning to become pregnant, discuss with your doctor the safest treatment options for your condition.
Does Nimodipine have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Nimodipine include low blood pressure, dizziness, and flushing. Serious side effects can include heart palpitations and swelling of the ankles or feet. If you experience any severe or concerning symptoms, contact your doctor immediately.
Does Nimodipine have any safety warnings?
Yes, Nimodipine has important safety warnings. It should not be given intravenously as it can cause serious side effects, including death. It's important to take it only by mouth. Not adhering to this warning can lead to severe cardiovascular complications. Always follow your doctor's instructions and the prescription label carefully.
Is it safe to drink alcohol while taking Nimodipine?
It's best to avoid alcohol while taking Nimodipine. Alcohol can increase the risk of side effects like dizziness and low blood pressure. If you choose to drink, limit your intake and watch for symptoms like dizziness or fainting. Discuss alcohol use with your doctor for personalized advice.
Is it safe to exercise while taking Nimodipine?
You can exercise while taking Nimodipine, but be cautious. This medication can cause dizziness or low blood pressure, especially during physical activity. Stay hydrated and avoid strenuous activities if you feel dizzy or lightheaded. Consult your doctor about your exercise routine while on Nimodipine.
Is it safe to stop Nimodipine?
Nimodipine is usually used for short-term treatment after a specific type of brain hemorrhage. Stopping it suddenly without your doctor's advice can be risky. Always consult your doctor before stopping Nimodipine to ensure it's safe and won't affect your recovery.
Is Nimodipine addictive?
Nimodipine is not addictive or habit-forming. It doesn't cause dependency or withdrawal symptoms when you stop taking it. This medication works by affecting calcium channels in the brain to improve blood flow, and it doesn't affect brain chemistry in ways that could lead to addiction.
Is Nimodipine safe for the elderly?
Elderly individuals may be more sensitive to Nimodipine's effects, such as low blood pressure or dizziness. It's important to monitor for these side effects. Your doctor may adjust the dose to ensure safety. Regular check-ups are essential to manage any potential risks.
What are the most common side effects of Nimodipine?
Side effects are unwanted reactions to a medication. Common side effects of Nimodipine include dizziness, headache, and flushing. These effects are usually mild and temporary. If you notice new symptoms after starting Nimodipine, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking Nimodipine?
Nimodipine should not be used if you are allergic to it or its ingredients. It's contraindicated for intravenous use due to severe risks. Caution is needed if you have low blood pressure or liver problems. Always consult your doctor about your medical history before starting Nimodipine.
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