Nilutamide
Prostatic Neoplasms, Carcinoma
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Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
YES
Known Teratogen
No
Pharmaceutical Class
Androgen Receptor Inhibitor
Controlled Drug Substance
No
nilutamide
Summary
Nilutamide is used to treat prostate cancer, which is a type of cancer that occurs in the prostate gland in men. It helps slow the progression of the disease by blocking male hormones that can promote cancer growth.
Nilutamide works by blocking the effects of male hormones, which are chemicals in the body that can promote the growth of prostate cancer cells. This action helps slow down the progression of the cancer.
The usual starting dose of Nilutamide for adults is 300 mg once daily for the first 30 days, then reduced to 150 mg once daily. It is taken orally, which means by mouth, and should be swallowed whole.
Common side effects of Nilutamide include hot flashes, which are sudden feelings of warmth, nausea, which is feeling sick to your stomach, and visual disturbances, which are changes in how you see things.
Nilutamide can cause liver problems, so regular liver function tests are necessary. It should not be used if you have severe liver issues or are allergic to it. Caution is needed if you have a history of lung disease or vision problems.
Indications and Purpose
How does Nilutamide work?
Nilutamide works by blocking the effects of male hormones, which can promote the growth of prostate cancer cells. Think of it like turning off a switch that fuels cancer growth. By blocking these hormones, Nilutamide helps slow the progression of prostate cancer. This medication is often used in combination with other treatments to improve outcomes. Always follow your doctor's advice and treatment plan when using Nilutamide.
Is Nilutamide effective?
Nilutamide is effective for treating prostate cancer. It works by blocking the effects of male hormones that can promote cancer growth. Clinical studies show that Nilutamide helps slow the progression of prostate cancer and improve survival rates. It's often used in combination with other treatments for better results. Always follow your doctor's advice and treatment plan to ensure the best outcomes.
What is Nilutamide?
Nilutamide is a medication used to treat prostate cancer. It belongs to a class of drugs called antiandrogens, which block the effects of male hormones that can promote cancer growth. Nilutamide is often used in combination with other treatments, such as surgery or radiation, to improve outcomes. It helps slow the progression of prostate cancer and improve survival rates. Always follow your doctor's advice and treatment plan when using Nilutamide.
Directions for Use
For how long do I take Nilutamide?
Nilutamide is usually a long-term medication for managing prostate cancer. You'll typically take it every day as part of your treatment plan. Stopping this medication without medical advice could cause your condition to worsen. How long you'll need this medication depends on your body's response, any side effects you experience, and changes in your overall health. Always talk with your doctor before changing or stopping your Nilutamide treatment.
How do I dispose of Nilutamide?
Dispose of Nilutamide by taking it to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of it properly to prevent harm to people or the environment. If you can't find a take-back program, you can throw it in the trash at home. First, mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away.
How do I take Nilutamide?
Take Nilutamide as directed by your doctor, usually once daily. You can take it with or without food. Swallow the tablet whole; do not crush or chew it. If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not take two doses at once. Avoid alcohol while taking Nilutamide, as it can increase side effects. Always follow your doctor's specific instructions regarding diet and fluid intake while on this medication.
How long does it take for Nilutamide to start working?
Nilutamide starts working in your body shortly after you take it, but the full therapeutic effects may take several weeks to become noticeable. The time it takes to work can depend on individual factors like your overall health and how your body responds to the medication. Regular check-ups and blood tests are important to monitor its effectiveness. Always take Nilutamide exactly as prescribed for the best results.
How should I store Nilutamide?
Store Nilutamide at room temperature, away from moisture and light. Keep it in a tightly closed container. Do not store it in humid places like bathrooms, as moisture can affect the medication's effectiveness. Always keep Nilutamide out of children's reach to prevent accidental swallowing. Check the expiration date regularly and properly dispose of any unused or expired medication.
What is the usual dose of Nilutamide?
The usual starting dose of Nilutamide for adults is 300 mg once daily for the first 30 days, then reduced to 150 mg once daily. It's important to follow your doctor's instructions for dosing. Dose adjustments may be necessary based on your response to the medication and any side effects you experience. Always consult your doctor for specific dosing instructions tailored to your health needs.
Warnings and Precautions
Can I take Nilutamide with other prescription drugs?
Nilutamide can interact with certain medications, increasing the risk of side effects. It may interact with blood thinners, increasing bleeding risk, and with certain antidepressants, affecting their effectiveness. Always inform your doctor about all medications you take to prevent interactions. Your doctor can adjust your treatment plan to ensure safety and effectiveness.
Can Nilutamide be taken safely while breastfeeding?
Nilutamide is not recommended while breastfeeding. There is limited information on whether it passes into human breast milk, but it could pose risks to a nursing infant. If you're taking Nilutamide and want to breastfeed, talk with your doctor about safer medication options that would allow you to nurse your baby safely.
Can Nilutamide be taken safely while pregnant?
Nilutamide is not recommended during pregnancy. It can harm an unborn baby. There is limited information on its use in pregnant women, but the risks are significant. If you're pregnant or planning to become pregnant, talk with your doctor about safer treatment options. Your doctor can help create a treatment plan that protects both you and your baby.
Does Nilutamide have adverse effects?
Adverse effects are unwanted reactions to a medication. Nilutamide can cause adverse effects like hot flashes, nausea, and liver problems. These effects vary in frequency and severity. Liver issues are serious and require immediate medical attention. If you notice symptoms like yellowing of the skin or eyes, contact your doctor. Always inform your doctor about any new or worsening symptoms while taking Nilutamide to ensure safe and effective treatment.
Does Nilutamide have any safety warnings?
Yes, Nilutamide has important safety warnings. It can cause liver problems, so regular liver function tests are necessary. Symptoms like nausea, vomiting, or yellowing of the skin require immediate medical attention. Nilutamide can also affect vision, causing difficulty adapting to darkness. If you experience vision changes, contact your doctor. Adhering to these warnings is crucial to prevent serious health issues. Always follow your doctor's advice and report any new or worsening symptoms.
Is it safe to drink alcohol while taking Nilutamide?
It's best to avoid alcohol while taking Nilutamide. Alcohol can increase the risk of liver problems, which are a concern with this medication. Drinking alcohol may also worsen side effects like dizziness or nausea. If you choose to drink occasionally, limit your alcohol intake and watch for warning signs like nausea or vomiting. Talk with your doctor about alcohol use while taking Nilutamide for personalized advice.
Is it safe to exercise while taking Nilutamide?
You can exercise while taking Nilutamide, but be cautious. This medication can cause dizziness or fatigue, which might affect your exercise capacity. To exercise safely, drink plenty of water before, during, and after physical activity. Watch for signs of dizziness or unusual fatigue. If you notice these symptoms, slow down or stop exercising and rest. Check with your doctor if you have concerns about your specific situation.
Is it safe to stop Nilutamide?
Stopping Nilutamide suddenly can affect your treatment. It's used long-term for prostate cancer, and stopping it may worsen your condition. Always talk with your doctor before stopping Nilutamide. They might suggest gradually reducing your dose or switching to a different medication to keep your condition under control. Your doctor will help you make any medication changes safely to protect your health.
Is Nilutamide addictive?
Nilutamide is not considered addictive or habit-forming. It does not cause dependency or withdrawal symptoms when you stop taking it. Nilutamide works by blocking certain hormones in the body, which doesn't affect brain chemistry in ways that could lead to addiction. You won't experience cravings for this medication or feel compelled to take more than prescribed. If you have concerns about medication dependence, you can feel confident that Nilutamide doesn't carry this risk.
Is Nilutamide safe for the elderly?
Elderly patients may be more vulnerable to the side effects of Nilutamide, such as liver problems and vision changes. These risks require careful monitoring. It's important for elderly patients to have regular check-ups and follow their doctor's advice closely. If you are elderly and taking Nilutamide, report any new or worsening symptoms to your doctor promptly.
What are the most common side effects of Nilutamide?
Side effects are unwanted reactions to a medication. Common side effects of Nilutamide include hot flashes, nausea, and visual disturbances. These effects vary from person to person. If you experience new symptoms after starting Nilutamide, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication. They can help determine if the side effects are related to Nilutamide and suggest ways to manage them.
Who should avoid taking Nilutamide?
Nilutamide should not be used if you have severe liver problems or are allergic to it. These are absolute contraindications due to severe risks. Caution is needed if you have a history of lung disease or vision problems. In these cases, the drug may be used only if benefits outweigh risks. Always consult your doctor about your medical history before starting Nilutamide.
