Nicardipine
Hypertension, Variant Angina Pectoris ... show more
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Dihydropyridine Calcium Channel Blocker
Controlled Drug Substance
No
nicardipine
Summary
Nicardipine is used to treat high blood pressure, which is when the force of blood against artery walls is too high, and angina, which is chest pain caused by reduced blood flow to the heart. It helps improve blood flow and reduce the risk of heart attacks and strokes.
Nicardipine is a calcium channel blocker, which means it relaxes blood vessels by blocking calcium from entering the cells of the heart and blood vessel walls. This action helps lower blood pressure and reduce chest pain by improving blood flow.
The usual starting dose of Nicardipine for adults is 20 mg, taken three times a day. It is taken orally, which means by mouth, and can be taken with or without food. The maximum recommended dose is 120 mg per day.
Common side effects of Nicardipine include dizziness, which is a feeling of being unsteady, headache, which is pain in the head, and flushing, which is a warm, red feeling in the skin. These effects are usually mild and temporary.
Nicardipine can cause low blood pressure, which is when blood pressure is lower than normal, leading to dizziness or fainting. It should not be used by people with severe aortic stenosis, which is a narrowing of the heart's aortic valve, as it can worsen heart function.
Indications and Purpose
How does Nicardipine work?
Nicardipine is a calcium channel blocker, which works by relaxing blood vessels to improve blood flow and lower blood pressure. It blocks calcium from entering the cells of the heart and blood vessel walls. Think of it like opening a valve to allow more water to flow through a pipe. This action helps reduce the workload on the heart and decreases chest pain, making it effective for treating high blood pressure and angina.
Is Nicardipine effective?
Nicardipine is effective in treating high blood pressure and certain types of chest pain, known as angina. It works by relaxing blood vessels, which improves blood flow and lowers blood pressure. Clinical studies support its effectiveness in managing these conditions. By controlling blood pressure, Nicardipine helps reduce the risk of heart attacks and strokes. Always follow your doctor's instructions to achieve the best results with this medication.
What is Nicardipine?
Nicardipine is a medication used to treat high blood pressure and angina, which is chest pain caused by reduced blood flow to the heart. It belongs to a class of drugs called calcium channel blockers, which work by relaxing blood vessels and improving blood flow. This helps lower blood pressure and reduce chest pain. Nicardipine is often used in combination with other therapies to manage these conditions effectively.
Directions for Use
For how long do I take Nicardipine?
Nicardipine is usually taken long-term for managing chronic conditions like hypertension. The duration of use depends on your health needs and how well you respond to treatment. Your doctor will guide you on how long to take Nicardipine based on your condition and any side effects you experience. Always talk with your doctor before changing or stopping your Nicardipine treatment.
How do I dispose of Nicardipine?
To dispose of Nicardipine, take it to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of it properly to prevent harm to people or the environment. If you can't find a take-back program, you can throw it in the trash at home. First, mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and then throw it away.
How do I take Nicardipine?
Take Nicardipine as prescribed by your doctor. It's usually taken orally, two or three times a day. You can take it with or without food. Swallow the capsules whole; do not crush or chew them. If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not double up on doses. Always follow your doctor's specific instructions regarding your medication.
How long does it take for Nicardipine to start working?
Nicardipine starts working within 1 to 2 hours after taking it, but it may take a few days to see the full effect on blood pressure. The time it takes to achieve full therapeutic effect can vary based on individual factors like age, kidney function, and overall health. It's important to take Nicardipine exactly as prescribed for the best results. Regular monitoring of blood pressure will help track its effectiveness.
How should I store Nicardipine?
Store Nicardipine at room temperature, away from moisture and light. Keep it in a tightly closed container. Avoid storing it in humid places like bathrooms, as moisture can affect the medication's effectiveness. Always keep Nicardipine out of reach of children to prevent accidental ingestion. Check the expiration date regularly and dispose of any unused or expired medication properly.
What is the usual dose of Nicardipine?
The usual starting dose of Nicardipine for adults is 20 mg, taken three times a day. Your doctor may adjust the dose based on your response and needs. The maximum recommended dose is 120 mg per day. For elderly patients or those with liver problems, dose adjustments may be necessary. Always follow your doctor's specific dosing instructions for your health needs.
Warnings and Precautions
Can I take Nicardipine with other prescription drugs?
Nicardipine can interact with other medications, increasing the risk of side effects or reducing effectiveness. Major interactions include beta-blockers, which can cause low blood pressure or heart rate. Moderate interactions include other blood pressure medications, which may enhance Nicardipine's effects. Always inform your doctor about all medications you're taking to avoid potential interactions and ensure safe treatment.
Can Nicardipine be taken safely while breastfeeding?
The safety of Nicardipine while breastfeeding is not well-established. It's unclear if it passes into breast milk or affects milk supply. If you're breastfeeding or planning to breastfeed, talk with your doctor. They can help determine if Nicardipine is the best option for you and your baby, or if an alternative medication might be safer.
Can Nicardipine be taken safely while pregnant?
The safety of Nicardipine during pregnancy is not well-established. It's important to weigh the benefits and risks with your doctor. Animal studies have shown some risks, but human data is limited. If you're pregnant or planning to become pregnant, discuss with your doctor the safest way to manage your condition. They can help create a treatment plan that protects both you and your baby.
Does Nicardipine have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Nicardipine include dizziness, headache, and flushing. These effects are usually mild and temporary. Serious side effects, like severe low blood pressure or heart problems, are rare but require immediate medical attention. If you experience any new or worsening symptoms, contact your doctor. They can help determine if these are related to Nicardipine and advise on the best course of action.
Does Nicardipine have any safety warnings?
Yes, Nicardipine has important safety warnings. It can cause low blood pressure, especially when starting treatment or increasing the dose. This may lead to dizziness or fainting. If you experience these symptoms, sit or lie down until they pass. Nicardipine can also affect heart rate and should be used cautiously in people with certain heart conditions. Not adhering to these warnings can lead to serious health issues. Always follow your doctor's advice and report any unusual symptoms.
Is it safe to drink alcohol while taking Nicardipine?
It's best to limit alcohol while taking Nicardipine. Alcohol can increase the risk of side effects like dizziness or low blood pressure. If you choose to drink, do so in moderation and be aware of how your body responds. If you experience symptoms like dizziness or fainting, stop drinking and talk with your doctor. They can provide personalized advice based on your health situation.
Is it safe to exercise while taking Nicardipine?
Yes, you can exercise while taking Nicardipine, but be cautious. This medication can cause dizziness or low blood pressure, especially when starting treatment. Stay hydrated and avoid strenuous activities until you know how Nicardipine affects you. If you feel dizzy or lightheaded during exercise, stop and rest. Consult your doctor for personalized advice on safe exercise routines.
Is it safe to stop Nicardipine?
Nicardipine is often used for long-term management of conditions like hypertension. Stopping it suddenly can cause your blood pressure to rise quickly, which may be dangerous. Always talk with your doctor before stopping Nicardipine. They may suggest gradually reducing your dose or switching to another medication to keep your condition under control. Your doctor will help you make any medication changes safely to protect your health.
Is Nicardipine addictive?
Nicardipine is not addictive or habit-forming. It does not cause dependency or withdrawal symptoms when you stop taking it. Nicardipine works by relaxing blood vessels to improve blood flow and lower blood pressure. This mechanism does not affect brain chemistry in ways that could lead to addiction. If you have concerns about medication dependence, you can feel confident that Nicardipine doesn't carry this risk.
Is Nicardipine safe for the elderly?
Elderly patients may be more sensitive to the effects of Nicardipine, such as dizziness or low blood pressure. It's important to start with a lower dose and monitor for side effects. Regular check-ups with your doctor are essential to ensure the medication is working safely and effectively. Always follow your doctor's advice and report any unusual symptoms.
What are the most common side effects of Nicardipine?
Side effects are unwanted reactions to a medication. Common side effects of Nicardipine include dizziness, headache, and flushing. These occur in a small percentage of people and are usually mild. If you experience these symptoms, they might be temporary or unrelated to the medication. It's important to talk with your doctor if you notice new symptoms after starting Nicardipine. They can help determine if the symptoms are related to the medication and advise on the best course of action.
Who should avoid taking Nicardipine?
Do not use Nicardipine if you have a known allergy to it or its ingredients. It's also contraindicated in people with severe aortic stenosis, which is a narrowing of the heart's aortic valve, as it can worsen heart function. Use caution if you have liver problems or heart failure. Always consult your doctor about your medical history before starting Nicardipine to ensure it's safe for you.
