Montelukast

Perennial Allergic Rhinitis, Asthma

Drug Status

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Government Approvals

US(FDA), UK(BNF)

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WHO Essential Medicine

NO

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Known Teratogen

NO

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Pharmaceutical Class

Leukotriene Receptor Antagonist

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Controlled Drug Substance

No

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Drug Ingredient

Montelukast

Summary

  • Montelukast is used to treat asthma, which is a condition causing breathing difficulties, and allergic rhinitis, which is inflammation of the nasal passages due to allergies. It helps reduce symptoms like wheezing, shortness of breath, and runny nose.

  • Montelukast works by blocking leukotrienes, which are substances in the body that cause allergy and asthma symptoms. By stopping these substances, it reduces inflammation and eases symptoms like wheezing and runny nose.

  • For adults and teenagers 15 years and older, the usual dose is 10 mg once daily in the evening. For children aged 6 to 14 years, it's typically 5 mg, and for those aged 2 to 5 years, it's usually 4 mg, all taken once daily in the evening.

  • Common side effects of Montelukast include headache, stomach pain, and sore throat. These effects are generally mild and occur in a small percentage of people taking the medication.

  • Montelukast may cause mood changes, including agitation, depression, or suicidal thoughts. It can also cause allergic reactions. People with a history of mental health issues should use it with caution. Always consult your doctor about these concerns.

Indications and Purpose

How does Montelukast work?

Montelukast works by blocking leukotrienes, which are substances in the body that cause allergy and asthma symptoms. Think of leukotrienes as messengers that tell your body to react to allergens. Montelukast stops these messages, reducing inflammation and easing symptoms like wheezing and runny nose. This makes it effective for managing asthma and allergic rhinitis.

Is Montelukast effective?

Montelukast is effective in managing asthma and allergic rhinitis, which is inflammation of the nasal passages due to allergies. It works by blocking substances in the body that cause allergy and asthma symptoms. Clinical studies show Montelukast improves asthma control and reduces allergy symptoms. It is often used as part of a comprehensive treatment plan.

What is Montelukast?

Montelukast is a medication used to manage asthma and allergic rhinitis, which is inflammation of the nasal passages due to allergies. It belongs to a class of drugs called leukotriene receptor antagonists, which work by blocking substances in the body that cause allergy and asthma symptoms. Montelukast is often used as part of a comprehensive treatment plan for these conditions.

Directions for Use

For how long do I take Montelukast?

Montelukast is usually taken long-term for managing chronic conditions like asthma or allergies. You'll typically take it every day as part of your ongoing treatment plan. How long you'll need this medication depends on your body's response and any side effects you experience. Always talk with your doctor before changing or stopping your Montelukast treatment.

How do I dispose of Montelukast?

Dispose of Montelukast by taking it to a drug take-back program or collection site at a pharmacy or hospital. If you can't find a take-back program, you can throw it in the trash at home. First, mix it with something undesirable like used coffee grounds, seal the mixture in a plastic bag, and throw it away.

How do I take Montelukast?

Take Montelukast once daily in the evening, with or without food. Swallow the tablet whole; do not crush it. If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not take two doses at once. There are no specific dietary or beverage restrictions while taking Montelukast, but always follow your doctor's advice.

How long does it take for Montelukast to start working?

Montelukast starts working within a few hours of taking it, but it may take several days to achieve its full effect. The time it takes to notice improvement can vary based on individual factors like the severity of your condition and your body's response. Consistent use as prescribed is important for the best results. Always follow your doctor's instructions.

How should I store Montelukast?

Store Montelukast at room temperature, away from moisture and light. Keep it in its original container with the lid tightly closed. Do not store it in the bathroom, where humidity can affect the medication. Always keep Montelukast out of reach of children to prevent accidental ingestion. Check the expiration date regularly and dispose of any expired medication properly.

What is the usual dose of Montelukast?

The usual dose of Montelukast for adults and teenagers 15 years and older is 10 mg once daily in the evening. For children aged 6 to 14 years, the dose is typically 5 mg once daily in the evening. For children aged 2 to 5 years, the dose is usually 4 mg once daily in the evening. Always follow your doctor's specific dosing instructions for your personal health needs.

Warnings and Precautions

Can I take Montelukast with other prescription drugs?

Montelukast has no major drug interactions, but it may interact with certain medications like phenobarbital, which is used to treat seizures. This interaction can reduce the effectiveness of Montelukast. Always inform your doctor about all the medications you are taking to avoid potential interactions. They can adjust your treatment plan as needed.

Can Montelukast be taken safely while breastfeeding?

Montelukast is generally considered safe to use while breastfeeding. It is not known to be excreted in significant amounts in breast milk. However, always discuss with your doctor before using Montelukast while breastfeeding. They can provide personalized advice based on your health needs and the well-being of your baby.

Can Montelukast be taken safely while pregnant?

The safety of Montelukast during pregnancy is not well-established. Limited data suggest it may be used if the benefits outweigh the risks. Always discuss with your doctor if you're pregnant or planning to become pregnant. They can help determine the safest treatment plan for managing your asthma or allergies during pregnancy.

Does Montelukast have adverse effects?

Adverse effects are unwanted reactions to a medication. Common adverse effects of Montelukast include headache, stomach pain, and sore throat. These effects are generally mild. Serious adverse effects, like mood changes or allergic reactions, are rare but require immediate medical attention. If you notice any new or worsening symptoms while taking Montelukast, contact your doctor.

Does Montelukast have any safety warnings?

Montelukast has important safety warnings. It may cause mood changes, including agitation, depression, or suicidal thoughts. If you experience these symptoms, contact your doctor immediately. Montelukast can also cause allergic reactions, which require immediate medical attention. Not adhering to these warnings can lead to serious health consequences. Always discuss any concerns with your healthcare provider.

Is it safe to drink alcohol while taking Montelukast?

There are no well-established interactions between Montelukast and alcohol. However, alcohol can worsen some side effects of Montelukast, like dizziness or drowsiness. It's best to limit alcohol consumption while taking this medication. If you choose to drink, do so in moderation and be aware of how your body responds. Discuss any concerns with your doctor.

Is it safe to exercise while taking Montelukast?

Yes, it's safe to exercise while taking Montelukast. This medication helps manage asthma, which can improve your ability to exercise. However, if you experience symptoms like dizziness or shortness of breath during physical activity, stop and rest. Always follow your doctor's advice on exercise and asthma management. They can provide guidance tailored to your health needs.

Is it safe to stop Montelukast?

Montelukast is often used long-term for chronic conditions like asthma or allergies. Stopping it suddenly may cause your symptoms to return or worsen. There are no withdrawal symptoms, but always talk with your doctor before stopping Montelukast. They can guide you on how to safely discontinue the medication if needed.

Is Montelukast addictive?

Montelukast is not addictive or habit-forming. It doesn't cause dependency or withdrawal symptoms when you stop taking it. Montelukast works by blocking substances in the body that cause allergy and asthma symptoms. This mechanism doesn't affect brain chemistry in ways that could lead to addiction. You won't experience cravings for this medication or feel compelled to take more than prescribed.

Is Montelukast safe for the elderly?

Montelukast is generally safe for the elderly, but they may be more sensitive to its side effects, such as dizziness or mood changes. The elderly are more vulnerable to medication risks due to age-related changes in the body. Regular monitoring by a healthcare provider is important to ensure safe and effective use of Montelukast in older adults.

What are the most common side effects of Montelukast?

Side effects are unwanted reactions to a medication. Common side effects of Montelukast include headache, stomach pain, and sore throat. These occur in a small percentage of people. If you notice new symptoms after starting Montelukast, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.

Who should avoid taking Montelukast?

Do not take Montelukast if you're allergic to it or its ingredients. Serious allergic reactions, which cause rash, hives, or swelling that makes breathing difficult, require immediate medical help. Montelukast should be used with caution in people with a history of mental health issues, as it may cause mood changes. Always consult your doctor about these concerns.