Metyrosine
Pheochromocytoma
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Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Catecholamine Synthesis Inhibitor
Controlled Drug Substance
No
Metyrosine
Summary
Metyrosine is used to treat pheochromocytoma, which is a type of tumor that can increase blood pressure. It helps manage symptoms like high blood pressure and headaches by reducing the production of certain chemicals in the body.
Metyrosine works by inhibiting the production of catecholamines, which are chemicals that can increase blood pressure. By reducing these chemicals, it helps lower blood pressure and manage symptoms of pheochromocytoma.
The usual starting dose of Metyrosine for adults is 250 mg four times a day. Your doctor may adjust the dose based on your response and needs. The maximum recommended dose is 4 grams per day.
Common side effects of Metyrosine include drowsiness, diarrhea, and dry mouth. These effects vary from person to person and are generally mild. Serious side effects, such as confusion or tremors, are rare but require immediate medical attention.
Metyrosine can cause drowsiness, so avoid driving until you know how it affects you. It may also cause dehydration, so drink plenty of fluids. It's not recommended during pregnancy or breastfeeding due to limited safety information.
Indications and Purpose
How does Metyrosine work?
Metyrosine works by inhibiting the production of catecholamines, which are chemicals that can increase blood pressure. Think of it like turning down the volume on a loudspeaker. By reducing these chemicals, Metyrosine helps lower blood pressure and manage symptoms of pheochromocytoma, which is a type of tumor that can increase blood pressure. This makes it effective in controlling the condition.
Is Metyrosine effective?
Metyrosine is effective in treating pheochromocytoma, which is a type of tumor that can increase blood pressure. It works by reducing the production of certain chemicals in the body that can raise blood pressure. Clinical studies support its effectiveness in managing symptoms associated with this condition. Always follow your doctor's instructions to ensure the best outcomes.
What is Metyrosine?
Metyrosine is a medication used to treat pheochromocytoma, which is a type of tumor that can increase blood pressure. It belongs to a class of drugs that reduce the production of certain chemicals in the body. By doing so, it helps manage symptoms like high blood pressure and headaches. Metyrosine is usually used alongside other therapies to effectively control the condition.
Directions for Use
For how long do I take Metyrosine?
Metyrosine is usually taken long-term for managing pheochromocytoma, which is a type of tumor that can increase blood pressure. The duration of use depends on your body's response and any side effects you experience. Always talk with your doctor before changing or stopping your Metyrosine treatment to ensure your condition remains well-managed.
How do I dispose of Metyrosine?
To dispose of Metyrosine, take it to a drug take-back program or collection site at a pharmacy or hospital. If that's not possible, mix the medication with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away in the trash. This helps prevent harm to people and the environment.
How do I take Metyrosine?
Take Metyrosine as prescribed by your doctor, usually 3 to 4 times a day. You can take it with or without food. If you have trouble swallowing pills, ask your doctor if it can be crushed. If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose. Don't double up on doses. Always follow your doctor's specific instructions regarding diet and fluid intake while on this medication.
How long does it take for Metyrosine to start working?
Metyrosine starts working shortly after you take it, but the full therapeutic effect may take a few days to become noticeable. The time it takes to work can depend on individual factors like your overall health and the severity of your condition. Always take Metyrosine as prescribed for the best results and talk with your doctor if you have concerns about its effectiveness.
How should I store Metyrosine?
Store Metyrosine at room temperature, away from moisture and light. Keep it in a tightly closed container to protect it from damage. Don't store it in humid places like bathrooms. Always keep Metyrosine out of children's reach to prevent accidental swallowing. Check the expiration date regularly and dispose of any unused or expired medication properly.
What is the usual dose of Metyrosine?
The usual starting dose of Metyrosine for adults is 250 mg four times a day. Your doctor may adjust the dose based on your response and needs. The maximum recommended dose is 4 grams per day. Dose adjustments may be necessary for special populations, such as the elderly. Always follow your doctor's specific dosing instructions for your health needs.
Warnings and Precautions
Can I take Metyrosine with other prescription drugs?
Metyrosine can interact with other medications, increasing the risk of side effects. For example, it may enhance the effects of sedatives, leading to increased drowsiness. Always inform your doctor about all medications you're taking to avoid potential interactions. Your doctor can help adjust your treatment plan to ensure it's safe and effective.
Can Metyrosine be taken safely while breastfeeding?
Metyrosine is not recommended while breastfeeding. There's limited information on whether it passes into breast milk or its effects on a breastfed infant. If you're taking Metyrosine and want to breastfeed, talk with your doctor about safer medication options that would allow you to nurse your baby safely.
Can Metyrosine be taken safely while pregnant?
Metyrosine is not recommended during pregnancy due to limited safety information. Animal studies suggest potential risks, but human data is lacking. If you're pregnant or planning to become pregnant, talk with your doctor about the safest way to manage your condition. Your doctor can help create a treatment plan that protects both you and your baby.
Does Metyrosine have adverse effects?
Adverse effects are unwanted reactions to a medication. Metyrosine can cause side effects like drowsiness, diarrhea, or dry mouth. These effects are generally mild. Serious side effects, such as confusion or tremors, are rare but require immediate medical attention. Always inform your doctor about any new or worsening symptoms while taking Metyrosine to ensure your treatment is safe and effective.
Does Metyrosine have any safety warnings?
Yes, Metyrosine has safety warnings. It can cause drowsiness, so avoid driving or operating heavy machinery until you know how it affects you. It may also cause dehydration, so drink plenty of fluids. Not adhering to these warnings can lead to accidents or worsen side effects. Always follow your doctor's advice and report any unusual symptoms.
Is it safe to drink alcohol while taking Metyrosine?
It's best to avoid alcohol while taking Metyrosine. Alcohol can increase the risk of side effects like drowsiness and dizziness. If you choose to drink occasionally, limit your alcohol intake and watch for warning signs like increased drowsiness or dizziness. Talk with your doctor about alcohol use while taking Metyrosine for personalized advice.
Is it safe to exercise while taking Metyrosine?
You can exercise while taking Metyrosine, but be cautious. This medication can cause drowsiness or dizziness, which might affect your exercise capacity. To exercise safely, stay hydrated and avoid strenuous activities if you feel dizzy or lightheaded. Most people can maintain their regular exercise routine, but check with your doctor if you have concerns.
Is it safe to stop Metyrosine?
It's important to talk with your doctor before stopping Metyrosine. Stopping suddenly can cause your symptoms to return or worsen. Your doctor might suggest gradually reducing your dose to avoid any potential issues. They will help you make any medication changes safely to protect your health.
Is Metyrosine addictive?
Metyrosine is not addictive or habit-forming. It doesn't cause dependency or withdrawal symptoms when you stop taking it. Metyrosine works by affecting certain chemicals in the body, but it doesn't impact brain chemistry in ways that could lead to addiction. You won't experience cravings for this medication or feel compelled to take more than prescribed. If you have concerns about medication dependence, Metyrosine doesn't carry this risk.
Is Metyrosine safe for the elderly?
For elderly patients, Metyrosine should be used cautiously, starting at the lower end of the dosing range. This is due to the higher likelihood of decreased liver, kidney, or heart function, and the presence of other health conditions or medications.
What are the most common side effects of Metyrosine?
Side effects are unwanted reactions to a medication. Common side effects of Metyrosine include drowsiness, diarrhea, and dry mouth. These effects vary from person to person. If you notice new symptoms after starting Metyrosine, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication to ensure your treatment remains effective.
Who should avoid taking Metyrosine?
Metyrosine should not be used if you are allergic to it or its ingredients. Serious allergic reactions require immediate medical help. Use caution if you have kidney problems, as Metyrosine may worsen kidney function. Always consult your doctor about any concerns or conditions before starting Metyrosine to ensure it's safe for you.
