Mavorixafor
Infections, Warts ... show more
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Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
NA
Controlled Drug Substance
No
Mavorixafor
Summary
Mavorixafor is used to treat an immune disorder called WHIM syndrome. This condition reduces the body's ability to fight infections.
Mavorixafor works by blocking the CXCR4 receptor. This stops leukocytes from being retained in the bone marrow, increasing their circulation in the bloodstream and enhancing the body's ability to fight infections.
For adults and children over 12 years with a body weight over 50 kg, the recommended dose is 400 mg once daily. For those weighing 50 kg or less, the dose is 300 mg once daily. It should be taken on an empty stomach at least 30 minutes before food.
Common side effects include thrombocytopenia, rash, rhinitis, epistaxis, vomiting and dizziness. Serious side effects include unusual bruising or bleeding and nosebleeds.
Mavorixafor should not be used during pregnancy as it can cause fetal harm. It should also be avoided with strong CYP3A4 inhibitors and inducers, and supplements like St. John's Wort. It may increase the risk of side effects if taken with drugs metabolized by CYP2D6 and CYP3A4. It's not recommended for breastfeeding mothers.
Indications and Purpose
How does Mavorixafor work?
Mavorixafor works by affecting specific processes in the body to help manage certain health conditions. Your doctor can provide more information on the specific mechanism of action and how it benefits your health.
Is Mavorixafor effective?
Mavorixafor is effective for its approved uses. Clinical studies support its effectiveness in managing the conditions it treats. Your doctor can provide more information on how Mavorixafor can help with your specific health needs.
What is Mavorixafor?
Mavorixafor is a medication used to treat certain health conditions. It works by affecting specific processes in the body to help manage these conditions. Your doctor can provide more information on how Mavorixafor can help with your specific health needs.
Directions for Use
For how long do I take Mavorixafor?
Mavorixafor is usually a long-term medication for managing ongoing health conditions. How long you'll need this medication depends on your body's response, any side effects you experience, and changes in your overall health. Always talk with your doctor before changing or stopping your Mavorixafor treatment.
How do I dispose of Mavorixafor?
If you can, bring unused Mavorixafor to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of it properly. If you can't find a take-back program, you can throw it in the trash at home. Mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away.
How do I take Mavorixafor?
Take Mavorixafor as directed by your doctor. It's usually taken once daily. You can take it with or without food. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not take two doses at once. Always follow your doctor's specific instructions regarding food and drink while on this medication.
How long does it take for Mavorixafor to start working?
Mavorixafor begins working in your body shortly after you take it. However, you may not notice all the benefits right away. How quickly the medication works can depend on your overall health and the condition being treated. Take it exactly as prescribed for the best results.
How should I store Mavorixafor?
Store Mavorixafor at room temperature, away from moisture and light. Keep it in a tightly closed container. Don't store it in humid places like bathrooms. Always keep it out of children's reach to prevent accidental swallowing. Check the expiration date regularly and dispose of any unused or expired medication properly.
What is the usual dose of Mavorixafor?
The usual starting dose of Mavorixafor for adults is determined by your doctor based on your specific health needs. It's typically taken once daily. Your doctor may adjust your dose depending on how you respond to the medication. Always follow your doctor's specific dosing instructions for your personal health needs.
Warnings and Precautions
Can I take Mavorixafor with other prescription drugs?
Mavorixafor may have interactions with other prescription drugs. It's important to inform your doctor about all medications you are taking to avoid potential interactions. Your doctor can provide guidance on how to safely use Mavorixafor with other medications.
Can Mavorixafor be taken safely while breastfeeding?
Mavorixafor is not recommended while breastfeeding. If you're taking Mavorixafor and want to breastfeed, talk with your doctor about safer medication options that would allow you to nurse your baby safely.
Can Mavorixafor be taken safely while pregnant?
Mavorixafor isn't recommended during pregnancy. If you're pregnant or planning to become pregnant, talk with your doctor about the safest way to manage your health condition. Your doctor can help create a treatment plan that protects both you and your baby.
Does Mavorixafor have adverse effects?
Adverse effects are unwanted reactions to a medication. Mavorixafor can cause some adverse effects, but most people tolerate it well. If you notice any new or worsening symptoms while taking Mavorixafor, contact your doctor. They can help determine if these symptoms are related to the medication and suggest appropriate actions.
Does Mavorixafor have any safety warnings?
Yes, Mavorixafor has important safety warnings. It's crucial to follow your doctor's instructions and the prescription information. Not adhering to safety warnings can lead to serious health issues. If you experience any unusual symptoms or side effects, contact your healthcare provider immediately.
Is it safe to drink alcohol while taking Mavorixafor?
It's best to avoid alcohol while taking Mavorixafor. Alcohol can increase the risk of side effects and may interfere with the medication's effectiveness. Talk with your doctor about alcohol use while taking Mavorixafor to get personalized advice based on your specific health situation.
Is it safe to exercise while taking Mavorixafor?
You can exercise while taking Mavorixafor, but keep a few things in mind. This medication can cause dehydration, which might make you feel dizzy during exercise. To exercise safely, drink plenty of water before, during, and after physical activity. Watch for signs of dizziness or fatigue.
Is it safe to stop Mavorixafor?
Stopping Mavorixafor suddenly can cause issues with your health condition. Always talk with your doctor before stopping the medication. They might suggest gradually reducing your dose or switching to a different medication to keep your condition under control. Your doctor will help you make any medication changes safely.
Is Mavorixafor addictive?
Mavorixafor is not considered addictive or habit-forming. It doesn't cause dependency or withdrawal symptoms when you stop taking it. If you have concerns about medication dependence, discuss them with your doctor. They can provide reassurance and guidance on managing your health condition safely.
Is Mavorixafor safe for the elderly?
The elderly may be more vulnerable to safety risks with medications like Mavorixafor. It's important for older adults to be closely monitored by their healthcare provider while taking this medication. Your doctor can provide guidance on the safe use of Mavorixafor for elderly patients.
What are the most common side effects of Mavorixafor?
Side effects are unwanted reactions that can happen when taking a medication. With Mavorixafor, these effects vary from person to person. If you notice new symptoms after starting Mavorixafor, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking Mavorixafor?
Don't take Mavorixafor if you're allergic to it or its ingredients. Always consult your doctor about any concerns or conditions that might affect your use of Mavorixafor. They can help determine if this medication is safe for you.
