Maribavir
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Cytomegalovirus pUL97 Kinase Inhibitor
Controlled Drug Substance
No
maribavir
Summary
Maribavir is used to treat cytomegalovirus (CMV) infections, which are viral infections that can occur in people with weakened immune systems, especially those who have had organ transplants.
Maribavir works by inhibiting the replication of the cytomegalovirus, which means it stops the virus from multiplying, helping to control the infection and reduce symptoms.
The usual dose of Maribavir for adults is 400 mg taken twice daily. It is taken orally, which means by mouth, and can be taken with or without food.
Common side effects of Maribavir include taste changes, nausea, and diarrhea, which are usually mild and temporary.
Maribavir can cause serious side effects like liver problems and changes in heart rhythm. It should not be taken by people allergic to it or its ingredients.
Indications and Purpose
How does Maribavir work?
Maribavir works by inhibiting the replication of cytomegalovirus (CMV), which is a virus that can cause infections, especially in people with weakened immune systems. It targets the virus's ability to reproduce, helping to control the infection. This action helps reduce CMV levels in the body, improving symptoms and preventing complications.
Is Maribavir effective?
Maribavir is effective in treating cytomegalovirus (CMV) infections, particularly in patients who have undergone organ transplants. It works by inhibiting the virus's ability to replicate. Clinical studies show Maribavir effectively reduces CMV levels in the body, helping to manage and control the infection. Always follow your doctor's instructions to ensure the best outcomes from your treatment.
What is Maribavir?
Maribavir is an antiviral medication used to treat cytomegalovirus (CMV) infections, especially in patients who have had organ transplants. It works by inhibiting the virus's ability to replicate, helping to control the infection. Maribavir is usually used when other treatments have not been effective. Always follow your doctor's instructions when taking this medication.
Directions for Use
For how long do I take Maribavir?
Maribavir is usually taken for a specific duration as prescribed by your doctor, often for a few weeks to treat cytomegalovirus (CMV) infections. The length of treatment depends on your response to the medication and your doctor's recommendations. Always follow your doctor's instructions and complete the full course of treatment to ensure the infection is fully managed.
How do I dispose of Maribavir?
Dispose of unused Maribavir by taking it to a drug take-back program or collection site at a pharmacy or hospital. If you can't find a take-back program, you can throw it in the trash at home. First, mix it with something undesirable like used coffee grounds, seal the mixture in a plastic bag, and throw it away. This helps prevent harm to people and the environment.
How do I take Maribavir?
Take Maribavir exactly as your doctor prescribes. It's usually taken twice daily, with or without food. Swallow the tablets whole; do not crush or chew them. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not take two doses at once. Always follow your doctor's specific advice about diet and fluid intake while taking this medication.
How long does it take for Maribavir to start working?
Maribavir starts working shortly after you take it, but the full therapeutic effect may take several days to weeks. The time it takes to see improvement depends on your specific condition and response to the medication. Regular check-ups with your doctor are important to monitor your progress and adjust treatment as needed.
How should I store Maribavir?
Store Maribavir at room temperature, away from moisture and light. Keep it in its original container, tightly closed, and out of reach of children. Do not store it in humid places like bathrooms. Always check the expiration date and properly dispose of any unused or expired medication.
What is the usual dose of Maribavir?
The usual dose of Maribavir for adults is 400 mg taken twice daily. Your doctor may adjust your dose based on your specific health needs. Always follow your doctor's dosing instructions carefully. If you have any questions about your dose or how to take Maribavir, consult your healthcare provider for guidance.
Warnings and Precautions
Can I take Maribavir with other prescription drugs?
Maribavir can interact with certain medications, including those that affect liver enzymes. These interactions may increase the risk of side effects or reduce the effectiveness of Maribavir. Always inform your doctor about all the medications you are taking to avoid potential interactions. Your doctor can adjust your treatment plan to ensure safety and effectiveness.
Can Maribavir be taken safely while breastfeeding?
Maribavir is not recommended while breastfeeding due to limited information on its safety. It's unclear if Maribavir passes into human breast milk. If you're taking Maribavir and want to breastfeed, talk with your doctor about safer medication options that would allow you to nurse your baby safely.
Can Maribavir be taken safely while pregnant?
Maribavir is not recommended during pregnancy due to limited safety data. Animal studies suggest potential risks, but human data is lacking. If you're pregnant or planning to become pregnant, talk with your doctor about the safest way to manage your health. Your doctor can help create a treatment plan that protects both you and your baby.
Does Maribavir have adverse effects?
Adverse effects are unwanted reactions to a medication. Maribavir can cause side effects like taste changes, nausea, and diarrhea. These effects are usually mild. Serious side effects include liver problems and changes in heart rhythm. If you notice any new or worsening symptoms, contact your doctor immediately. Always inform your healthcare provider about any side effects you experience while taking Maribavir.
Does Maribavir have any safety warnings?
Yes, Maribavir has important safety warnings. It can cause serious side effects, including liver problems and changes in heart rhythm. If you experience symptoms like yellowing of the skin or eyes, dark urine, or irregular heartbeat, seek medical help immediately. Always follow your doctor's instructions and report any unusual symptoms while taking Maribavir.
Is it safe to drink alcohol while taking Maribavir?
It's best to avoid alcohol while taking Maribavir. Alcohol can increase the risk of liver problems, which is a potential side effect of Maribavir. If you choose to drink occasionally, limit your alcohol intake and watch for symptoms like nausea or yellowing of the skin. Talk with your doctor about alcohol use while taking Maribavir for personalized advice.
Is it safe to exercise while taking Maribavir?
You can exercise while taking Maribavir, but be mindful of your body's response. Maribavir can cause dizziness or fatigue, which might affect your exercise capacity. To exercise safely, stay hydrated and watch for signs of dizziness or unusual fatigue. If you notice these symptoms, slow down or stop exercising and rest. Consult your doctor if you have concerns about your specific situation.
Is it safe to stop Maribavir?
It's important not to stop Maribavir suddenly without consulting your doctor. Stopping the medication abruptly can affect your treatment's effectiveness. Your doctor may suggest gradually reducing your dose or switching to a different medication to keep your condition under control. Always talk with your doctor before making any changes to your medication regimen.
Is Maribavir addictive?
Maribavir is not addictive or habit-forming. This medication doesn't cause dependency or withdrawal symptoms when you stop taking it. If you have concerns about medication dependence, you can feel confident that Maribavir doesn't carry this risk while managing your health condition.
Is Maribavir safe for the elderly?
Elderly patients may be more vulnerable to side effects of Maribavir, such as liver problems or changes in heart rhythm. It's important for older adults to be closely monitored by their healthcare provider while taking this medication. Regular check-ups help ensure the medication is safe and effective for elderly patients.
What are the most common side effects of Maribavir?
Side effects are unwanted reactions that can happen when taking a medication. Common side effects of Maribavir include taste changes, nausea, and diarrhea. These effects vary from person to person. If you notice new symptoms after starting Maribavir, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking Maribavir?
Do not take Maribavir if you're allergic to it or its ingredients. Serious allergic reactions require immediate medical help. Maribavir should be used with caution in patients with liver problems or heart rhythm issues. Always consult your doctor about any health concerns before starting Maribavir to ensure it's safe for you.
