Maraviroc
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
CCR5 Co-receptor Antagonist
Controlled Drug Substance
No
maraviroc
Summary
Maraviroc is used to treat HIV-1 infection, which is a virus that attacks the immune system. It is part of a combination therapy to help control the virus and improve immune function.
Maraviroc works by blocking a protein called CCR5, which HIV uses to enter cells. This action helps reduce the viral load, which is the amount of virus in the body, and increases CD4 cell counts, which are important for a healthy immune system.
The usual starting dose of Maraviroc for adults is 300 mg taken twice daily. It is taken orally, which means by mouth, with or without food. Always follow your doctor's specific dosing instructions.
Common side effects of Maraviroc include dizziness, nausea, and diarrhea, which are unwanted reactions to the medication. These effects vary from person to person and should be discussed with a doctor if they occur.
Maraviroc can cause liver problems, so watch for symptoms like yellowing of the skin or eyes. It may also cause serious allergic reactions. Do not use Maraviroc if you have severe liver issues or are allergic to it.
Indications and Purpose
How does Maraviroc work?
Maraviroc works by blocking a protein called CCR5, which HIV uses to enter cells. Think of it like locking a door to keep the virus out. This helps control the virus in your body, reducing viral load and increasing CD4 cell counts, which are important for a healthy immune system.
Is Maraviroc effective?
Maraviroc is effective in treating HIV-1 infection. It works by blocking a protein that HIV uses to enter cells, helping to control the virus in your body. Clinical studies show Maraviroc reduces viral load and increases CD4 cell counts, which are important for a healthy immune system. Always follow your doctor's treatment plan.
What is Maraviroc?
Maraviroc is a medication used to treat HIV-1 infection. It belongs to a class of drugs called CCR5 antagonists, which block a protein that HIV uses to enter cells. This helps control the virus in your body. Maraviroc is used in combination with other HIV medications to improve treatment effectiveness.
Directions for Use
For how long do I take Maraviroc?
Maraviroc is usually a long-term medication for managing HIV-1 infection. You'll typically take it every day as part of your lifelong treatment unless your doctor suggests otherwise. How long you'll need this medication depends on your body's response and any side effects you experience. Always talk with your doctor before changing or stopping your Maraviroc treatment.
How do I dispose of Maraviroc?
Dispose of Maraviroc by taking it to a drug take-back program or collection site at a pharmacy or hospital. If you can't find a take-back program, mix the medication with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away in the trash.
How do I take Maraviroc?
Take Maraviroc exactly as prescribed by your doctor. It's usually taken twice daily, with or without food. Swallow the tablets whole; do not crush or chew them. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not take two doses at once. Always follow your doctor's specific instructions.
How long does it take for Maraviroc to start working?
Maraviroc begins working shortly after you take it, but you may not notice all the benefits right away. It helps control HIV by reducing viral load and increasing CD4 cell counts. Regular blood tests will help monitor these levels. Your doctor will adjust your treatment based on these test results.
How should I store Maraviroc?
Store Maraviroc at room temperature, away from moisture and light. Keep it in a tightly closed container. Don't store it in humid places like bathrooms. Always keep Maraviroc out of children's reach to prevent accidental swallowing. Check the expiration date regularly and properly dispose of any unused or expired medication.
What is the usual dose of Maraviroc?
The usual starting dose of Maraviroc for adults is 300 mg taken twice daily. Your doctor may adjust your dose based on your response to the medication and any other medications you are taking. It's important to follow your doctor's specific dosing instructions. Do not change your dose without consulting your healthcare provider.
Warnings and Precautions
Can I take Maraviroc with other prescription drugs?
Maraviroc can interact with certain medications, increasing the risk of side effects or reducing effectiveness. Drugs like rifampin and certain antifungals can affect Maraviroc levels. Always inform your doctor about all medications you're taking to avoid interactions. They can adjust your treatment plan to ensure safety and effectiveness.
Can Maraviroc be taken safely while breastfeeding?
Maraviroc's safety while breastfeeding isn't well-established. It's unclear if it passes into breast milk. Discuss with your doctor if you're breastfeeding or planning to breastfeed. They can help weigh the benefits and risks and decide the best treatment plan for you and your baby.
Can Maraviroc be taken safely while pregnant?
Maraviroc's safety during pregnancy isn't well-established. Limited data is available, so it's important to discuss with your doctor if you're pregnant or planning to become pregnant. They can help weigh the benefits and risks and decide the best treatment plan for you and your baby.
Does Maraviroc have adverse effects?
Adverse effects are unwanted reactions to a medication. Maraviroc can cause dizziness, nausea, and diarrhea, which are common side effects. Serious adverse effects include liver problems and severe allergic reactions. If you experience any new or worsening symptoms, contact your doctor immediately. They can help determine if these are related to Maraviroc.
Does Maraviroc have any safety warnings?
Yes, Maraviroc has important safety warnings. It can cause liver problems, so watch for symptoms like yellowing of the skin or eyes, dark urine, or stomach pain. Maraviroc may also cause serious allergic reactions, which require immediate medical attention. Always follow your doctor's advice and report any unusual symptoms.
Is it safe to drink alcohol while taking Maraviroc?
It's best to limit alcohol while taking Maraviroc. Alcohol can increase the risk of liver problems, which Maraviroc can also cause. If you choose to drink, do so in moderation and watch for symptoms like nausea or yellowing of the skin. Talk with your doctor about alcohol use while on Maraviroc.
Is it safe to exercise while taking Maraviroc?
You can exercise while taking Maraviroc, but be mindful of how your body feels. Maraviroc can cause dizziness, which might affect your balance during exercise. Stay hydrated and avoid strenuous activities if you feel dizzy. Most people can maintain their regular exercise routine, but check with your doctor if you have concerns.
Is it safe to stop Maraviroc?
Stopping Maraviroc suddenly can affect your HIV treatment. It may lead to an increase in viral load, which is the amount of HIV in your blood, and worsen your condition. Always talk with your doctor before stopping Maraviroc. They might suggest a different medication or a gradual reduction to keep your condition under control.
Is Maraviroc addictive?
Maraviroc is not addictive or habit-forming. It doesn't cause dependency or withdrawal symptoms when you stop taking it. Maraviroc works by blocking a protein that HIV uses to enter cells, and this mechanism doesn't affect brain chemistry in ways that could lead to addiction. You won't experience cravings for this medication.
Is Maraviroc safe for the elderly?
Elderly patients may have a higher risk of side effects due to age-related changes in liver and kidney function. Caution is advised, and dosage adjustments may be necessary. Regular monitoring by a healthcare provider is recommended.
What are the most common side effects of Maraviroc?
Side effects are unwanted reactions to a medication. Common side effects of Maraviroc include dizziness, nausea, and diarrhea. These effects vary from person to person. If you notice new symptoms after starting Maraviroc, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking Maraviroc?
Don't take Maraviroc if you're allergic to it or its ingredients. Serious allergic reactions require immediate medical help. Maraviroc shouldn't be used by people with severe liver problems. Always consult your doctor about any health conditions you have before starting Maraviroc to ensure it's safe for you.
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