Loratadine + Pseudoephedrine
Find more information about this combination medication at the webpages for loratadine and pseudoephedrine
Perennial Allergic Rhinitis , Asthma ... show more
Drug Status
Government Approvals
None
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
Alpha-Adrenergic Agonist and Histamine-1 Receptor Antagonist
Controlled Drug Substance
NO
Summary
Loratadine and pseudoephedrine are used to relieve symptoms of allergic rhinitis, which is a condition with sneezing, runny nose, and itchy eyes due to allergies. They also help with nasal congestion and sinus pressure from colds or allergies. Loratadine targets allergy symptoms, while pseudoephedrine focuses on nasal congestion, providing comprehensive relief for these conditions.
Loratadine, an antihistamine, works by blocking histamine, which is a substance causing allergic symptoms like sneezing and itching. Pseudoephedrine, a decongestant, narrows blood vessels in the nasal passages, reducing swelling and congestion. Together, they provide relief from both allergy symptoms and nasal congestion, improving breathing and comfort.
The usual adult dose for loratadine and pseudoephedrine is one tablet taken once or twice a day, depending on the product. Loratadine is typically dosed at 10 mg, while pseudoephedrine is often 240 mg in extended-release forms. It's important to follow package instructions or a healthcare provider's guidance for safe and effective use.
Common side effects of loratadine and pseudoephedrine include dry mouth, headache, and dizziness. Loratadine may cause drowsiness in some people, although it's generally non-drowsy. Pseudoephedrine can cause nervousness, restlessness, and trouble sleeping. Monitoring for these effects is important, especially in individuals with heart conditions.
Loratadine and pseudoephedrine should be avoided in individuals with severe high blood pressure or heart disease. Loratadine requires caution in those with liver or kidney issues. Pseudoephedrine is contraindicated with MAOIs, a type of antidepressant, due to severe blood pressure risks. Always consult a healthcare provider before use, especially with pre-existing conditions.
Indications and Purpose
How does combination of Loratadine and Pseudoephedrine work?
Loratadine and Pseudoephedrine work together to relieve symptoms of allergies and nasal congestion. Loratadine is an antihistamine, which means it helps reduce allergy symptoms like sneezing, runny nose, and itchy eyes by blocking the action of histamine, a substance in the body that causes allergic reactions. Pseudoephedrine is a decongestant, which helps relieve nasal congestion by narrowing the blood vessels in the nasal passages, making it easier to breathe. Together, they provide comprehensive relief from allergy symptoms and congestion.
How effective is combination of Loratadine and Pseudoephedrine?
The combination of Loratadine and Pseudoephedrine is effective for relieving symptoms of allergies and nasal congestion. Loratadine is an antihistamine that helps reduce allergy symptoms like sneezing, runny nose, and itchy eyes by blocking the action of histamine, a substance in the body that causes allergic symptoms. Pseudoephedrine is a decongestant that works by narrowing the blood vessels in the nasal passages, leading to decreased swelling and congestion. According to the NHS, this combination can be particularly useful for people who experience both allergy symptoms and nasal congestion. However, it's important to use this medication as directed and be aware of potential side effects, such as increased heart rate or insomnia, due to the presence of Pseudoephedrine. For more detailed information, you can refer to resources like the NHS or DailyMeds.
Directions for Use
What is the usual dose of combination of Loratadine and Pseudoephedrine?
The usual dose for adults and children over 12 years old is one tablet containing 10 mg of Loratadine and 240 mg of Pseudoephedrine, taken once daily. This combination is used to relieve allergy symptoms and nasal congestion. It's important to follow the dosage instructions on the package or those given by a healthcare provider. Loratadine is an antihistamine that helps reduce allergy symptoms like sneezing and runny nose, while Pseudoephedrine is a decongestant that relieves nasal congestion. Always consult with a healthcare professional before starting any new medication.
How does one take combination of Loratadine and Pseudoephedrine?
Loratadine and Pseudoephedrine are often combined in a single medication to help relieve allergy symptoms and nasal congestion. Loratadine is an antihistamine that reduces the effects of natural histamines in the body, which can cause symptoms like sneezing, itching, and runny nose. Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages, helping to relieve nasal congestion. When taking this combination, it is important to follow the dosage instructions provided by your healthcare provider or as indicated on the medication packaging. Typically, this medication is taken by mouth, with or without food, usually once or twice a day. It is important not to exceed the recommended dose to avoid potential side effects. If you have any pre-existing health conditions or are taking other medications, consult with a healthcare professional before using this combination to ensure it is safe for you. Additionally, if you experience any severe side effects or allergic reactions, seek medical attention promptly.
For how long is combination of Loratadine and Pseudoephedrine taken?
The combination of Loratadine and Pseudoephedrine is typically taken for a short period, usually not exceeding 10 days. This is because Pseudoephedrine, a decongestant, can cause side effects if used for too long. It's important to follow the dosage instructions provided by a healthcare professional or the information on the medication package. If symptoms persist, consult a doctor for further advice.
How long does it take for combination of Loratadine and Pseudoephedrine to work?
The combination of Loratadine and Pseudoephedrine typically starts to work within 1 to 3 hours after taking it. Loratadine is an antihistamine that helps relieve allergy symptoms like sneezing and runny nose, while Pseudoephedrine is a decongestant that reduces nasal congestion. Together, they help alleviate symptoms of allergies and colds.
Warnings and Precautions
Are there harms and risks from taking combination of Loratadine and Pseudoephedrine?
Loratadine and Pseudoephedrine are often combined to treat symptoms of allergies and colds, such as runny nose, sneezing, and nasal congestion. However, there are potential risks and side effects associated with this combination. 1. **Side Effects**: Common side effects may include dry mouth, dizziness, headache, and trouble sleeping. Pseudoephedrine can also cause increased heart rate and blood pressure. 2. **Interactions**: This combination can interact with other medications, especially those for high blood pressure or heart conditions. It's important to consult a healthcare provider if you are taking other medications. 3. **Health Conditions**: People with certain health conditions, such as high blood pressure, heart disease, diabetes, or thyroid disorders, should be cautious and consult a doctor before using this combination. 4. **Overuse Risks**: Taking more than the recommended dose can lead to serious side effects, including severe dizziness, anxiety, and heart problems. Always follow the dosage instructions provided by a healthcare professional or the packaging, and consult a healthcare provider if you have any concerns or pre-existing health conditions.
Can I take combination of Loratadine and Pseudoephedrine with other prescription drugs?
Loratadine is an antihistamine used to relieve allergy symptoms, and Pseudoephedrine is a decongestant that relieves nasal congestion. When taking these medications together, it's important to be cautious about interactions with other prescription drugs. According to the NHS, you should always check with a healthcare professional before combining these with other medications, especially those that affect the heart or blood pressure, as Pseudoephedrine can increase heart rate and blood pressure. The NLM advises that you should also be cautious if you are taking medications that cause drowsiness, as Loratadine can sometimes cause drowsiness in some people. DailyMeds suggests that you inform your doctor about all the medications you are currently taking, including over-the-counter drugs and supplements, to avoid any potential interactions. In summary, consult with your healthcare provider to ensure that combining Loratadine and Pseudoephedrine with other prescription drugs is safe for you.
Can I take combination of Loratadine and Pseudoephedrine if I am pregnant?
It is generally advised to avoid taking Loratadine and Pseudoephedrine during pregnancy unless specifically recommended by a healthcare professional. Loratadine is an antihistamine used to relieve allergy symptoms, and Pseudoephedrine is a decongestant used to relieve nasal congestion. Both medications can have effects on pregnancy, and their safety has not been fully established. Always consult with your doctor or a healthcare provider before taking any medication during pregnancy to ensure it is safe for you and your baby.
Can I take combination of Loratadine and Pseudoephedrine while breastfeeding?
Loratadine is an antihistamine used to relieve allergy symptoms, and pseudoephedrine is a decongestant used to relieve nasal congestion. According to the NHS, loratadine is generally considered safe to use while breastfeeding as it passes into breast milk in small amounts and is unlikely to cause harm to a breastfeeding infant. However, pseudoephedrine can reduce milk supply and may cause irritability in some infants. The NLM advises that if you need to take pseudoephedrine, it should be used with caution and only if necessary. It's important to consult with a healthcare professional before taking these medications together while breastfeeding to ensure it's safe for you and your baby.
Who should avoid taking combination of Loratadine and Pseudoephedrine?
People who should avoid taking the combination of Loratadine and Pseudoephedrine include those with certain medical conditions or who are taking specific medications. According to the NHS and DailyMeds, individuals with high blood pressure, heart disease, diabetes, thyroid disorders, or glaucoma should be cautious or avoid this combination. Additionally, those who are pregnant or breastfeeding should consult a healthcare professional before use. It's also important for people taking monoamine oxidase inhibitors (MAOIs), a type of antidepressant, to avoid this combination due to potential interactions. Always consult a healthcare provider for personalized advice.

